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EF3030
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serotype 5
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serotype 3
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serotype 4
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serotype 1

NCBI: 15-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 70585
  • locus tag: SP70585_RS11440 [old locus tag: SP70585_2307 ]
  • pan locus tag?: PNEUPAN003876000
  • symbol: ltrA
  • pan gene symbol?: ltrA
  • synonym:
  • product: group II intron reverse transcriptase/maturase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP70585_RS11440 [old locus tag: SP70585_2307 ]
  • symbol: ltrA
  • product: group II intron reverse transcriptase/maturase
  • replicon: chromosome
  • strand: -
  • coordinates: 2122502..2123779
  • length: 1278
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTCAAAACTGCTAGATAAGATATTATCACGCGAAAATATGCTGGAAGCCTACAATCAA
    GTAAAATCCAATAAAGGCTCAGCTGGGATTGATGGAATGACTATCGAAGAGATGGATAAT
    TATCTCAGACAAAACTGGCGCTTGACTAAGGAACTGATAAAACAGAGAAAATATAAGCCT
    CAACCAGTTCTTAAAGTTGAGATACCTAAACCAGACGGAGGCATCCGTCAACTAGGAATT
    CCAACAGTTATGGATAGAATGATTCAACAGGCCATTGTCCAAGTCATGAGCCCCATTTGT
    GAACCCCATTTCTCAGATACGAGTTATGGTTTCAGACCAAATAGGTCATGTGAAAAAGCC
    ATCATGAAGCTCTTAGAATACTTAAATGACGGCTATGAGTGGATAGTGGATATAGACCTA
    GAGAAATTTTTCGATACAGTTCCTCAAGATAGATTGATGTCCTTAGTACATAACATTATC
    GAAGACGGAGATACGGAATCCTTGATTCGTAAGTATCTTCATTCAGGTGTTATCATTAAT
    GGTCAACGTTATAAAACACTAGTTGGTACACCACAGGGAGGAAATTTATCTCCTCTCTTA
    TCCAATATCATGCTTAATGAATTGGACAAGGAATTAGAAAAGAGGGGACTTCGATTTGTG
    CGCTACGCAGATGATTGTGTGATTACGGTCGGAAGCGAGGCAGCCTCTAAGCGTGTGATG
    TATTCAGTCAGTCGTTTTATTGAGAAACGGCTAGGTTTGAAAGTAAACATGACCAAGACT
    AAGATTACCAGACCAAGAGAGTTGAAATATCTAGGTTTTGGGTTCTGGAAATCATCAGAT
    GGTTGGAAAAGCCGTCCACATCAAGATAGTGTTCGGAGATTTAAGTTTAAATTGAAGAAA
    CTAACACAGAGGAAATGGAGTATAGACCTAACAAGACGTATTGAGCAACTGAATTTGTCT
    ATTCGAGGATGGATAAACTATTTCTCATTGGGAAATATGAAAAGTATAGTCGCCAGCATA
    GATGAGCGCTTGCGTACTCGCCTACGAGTGATTATCTGGAAGCAATGGAAGAAGAAATCG
    AGACGATTATGGGGATTGCTTAAGTTAGGAGTTCCTAAATGGATAGCAGATAAGGTATCT
    GGCTGGGGCGACCATTATCAATTAGTAGCTCAGAAGTCGGTACTTAAACGTGCTATATCA
    AAACCAGTCCTGGAAAAACGTGGACTGGTTTCGTGTTTGGATTATTACCTTGAACGACAT
    GCGTTAAAAGTTAGTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1278

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP70585_RS11440 [old locus tag: SP70585_2307 ]
  • symbol: LtrA
  • description: group II intron reverse transcriptase/maturase
  • length: 425
  • theoretical pI: 10.5536
  • theoretical MW: 49554.7
  • GRAVY: -0.457176

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.7.49?  ExPASy
    RNA-directed DNA polymerase Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Other group II intron reverse transcriptase/maturase (TIGR04416; EC 2.7.7.49; HMM-score: 422.7)
    and 2 more
    abortive infection protein, AbiA family (TIGR04499; HMM-score: 24)
    Unknown function General putative RNA-binding protein, YhbY family (TIGR00253; HMM-score: 12.7)
  • TheSEED: see SP70585_2307
  • PFAM:
    RdRP (CL0027) RVT_1; Reverse transcriptase (RNA-dependent DNA polymerase) (PF00078; HMM-score: 170.7)
    and 2 more
    Intron-mat_II (CL0359) GIIM; Group II intron, maturase-specific domain (PF08388; HMM-score: 66.5)
    Saposin_like (CL0707) SapB_1; Saposin-like type B, region 1 (PF05184; HMM-score: 14.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8851
    • Cytoplasmic Membrane Score: 0.0702
    • Cell wall & surface Score: 0.0215
    • Extracellular Score: 0.0232
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003704
    • TAT(Tat/SPI): 0.001133
    • LIPO(Sec/SPII): 0.00061
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQNWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEPHFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNIIEDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLRFVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFWKSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMKSIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQKSVLKRAISKPVLEKRGLVSCLDYYLERHALKVS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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