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serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_1984 [new locus tag: SPAP_RS09820 ]
  • pan locus tag?: PNEUPAN003590000
  • symbol: SPAP_1984
  • pan gene symbol?: yjfA
  • synonym:
  • product: rRNA methylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1984 [new locus tag: SPAP_RS09820 ]
  • symbol: SPAP_1984
  • product: rRNA methylase
  • replicon: chromosome
  • strand: -
  • coordinates: 1853918..1854658
  • length: 741
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGACTATTATAACCTCAAAAGCCAATTCTGTGGTAAAAAATGCTAAGAAATTACACCAA
    AAAAAATACCGCAAGTCTGCCTATTTGATTGAAGGCTGGCACTTGTTTGAAGAAGCTGTC
    CAAGCTGGAGTGACGATTGAGAAAATCTTTGCCCTAGAAAATTATCGAAATCAGTTAGCT
    GCTTTTCCGCAAACTGTCTGGATTTCAGAGGATATTTTGCTAGATTTGGCGGATTCTCAG
    ACTCCACAGGGAATTGTTGCCGTGGTTCAAAAAGAAGAAGTAGGACAAGCTGATTTGAGT
    CAGGGCAAGTTCTTGTTTTTGGAAGATGTGCAAGATCCTGGTAATGTAGGAACTATCATT
    CGAACTGCGGAGGCAGCAGGTTTTACAGGAGTGATTGTTTCAGATAAGTCGGCAGACATC
    TACAGTCTCAAAACCCTACGTTCCATGCAAGGTAGTCATTTCCATCTGCCCATTTACCGG
    ATGACTAGTCAAGCGCTTCTTGACGAAACTAAAAAGGTAGCTATCCCAGTGCTAGCAACA
    ACCCTATCTAAAGATTCTGTTGATTACAGAGAACTGCCTTCTATAGAAAATTTTGTACTA
    GTTATGGGAAATGAGGGTCAAGGAATTAGTCCCCTTATGGCTGAAAGTGCAGACCAGTTG
    GTCCATATTAGCATGAAGGGGCAGGCCGAGAGTTTGAATGTTGCAGTTGCAACCGGTATT
    TTAATCTTCCATTTAAGCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    741

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_1984 [new locus tag: SPAP_RS09820 ]
  • symbol: SPAP_1984
  • description: rRNA methylase
  • length: 246
  • theoretical pI: 5.62085
  • theoretical MW: 26961.7
  • GRAVY: 0.0284553

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification RNA methyltransferase, TrmH family, group 3 (TIGR00186; HMM-score: 122.6)
    and 2 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA (cytidine(34)-2'-O)-methyltransferase (TIGR00185; EC 2.1.1.207; HMM-score: 26.5)
    Genetic information processing Protein synthesis tRNA and rRNA base modification RNA methyltransferase, TrmH family, group 1 (TIGR00050; EC 2.1.1.-; HMM-score: 22.3)
  • TheSEED  :
    • FIG011178: rRNA methylase
  • PFAM:
    SPOUT (CL0098) SpoU_methylase; SpoU rRNA Methylase family (PF00588; HMM-score: 119.9)
    and 2 more
    PELOTA (CL0101) SpoU_sub_bind; RNA 2'-O ribose methyltransferase substrate binding (PF08032; HMM-score: 34.8)
    Leu-IlvD (CL0364) PA; PA domain (PF02225; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9982
    • Cytoplasmic Membrane Score: 0.001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0007
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002936
    • TAT(Tat/SPI): 0.000258
    • LIPO(Sec/SPII): 0.000357
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85546 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGVTIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQGKFLFLEDVQDPGNVGTIIRTAEAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYRMTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESADQLVHISMKGQAESLNVAVATGILIFHLS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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