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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-FEB-2023

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_RS06135 [old locus tag: SPAP_1240 ]
  • pan locus tag?: PNEUPAN002451000
  • symbol: SPAP_RS06135
  • pan gene symbol?: —
  • synonym:
  • product: DUF2130 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_RS06135 [old locus tag: SPAP_1240 ]
  • symbol: SPAP_RS06135
  • product: DUF2130 domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1176239..1177513
  • length: 1275
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_014494 (1176239..1177513) NCBI
  • BioCyc: SPAP_RS06135 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1072 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAACGAAATCAAATGTCCCAACTGTGGGGAAGTCTTTACAGTAAATGAAAGCCAGTAT
    GCTGAACTTTTGTCCCAAGTGAGAACGGCAGAGTTTGATAAGGAACTACACGATAGGATG
    AGGCAGGAACTGGCCTTGGCTGAGCAAAAGGCTATGAATGAGCAACAGACTAAACTGGCT
    CAGAAGGATCAAGAAATTGCGCAATTGCAGAGTCAAATCCAAAACTTTGATACAGAAAAA
    GAATTGGCCAAGAAAGAAGTTGAACAGACAAGCCATCAGGCCTTATTGGCTAAGGACAAG
    GAAGTACAGGCCTTGGAAAACCAGTTGGCGACCTTGCGTTTGGAGCATGAAAATCAATTG
    CAAAAGACCCTTTCTGACCTAGAAAAAGAACGCAATCAGGTCAAAAATCAGCTCCTACTG
    CAAGAAAAGGAAAATGAGTTGTCTTTGGCTTCTGTTAAGCAAAACTACGAAGCCCAGCTC
    AAAGCAGCCAGTGAACAAGTCGAGTTTTATAAGAATTTTAAGGCTCAACAATCTACAAAA
    GCGATTGGGGAAAGCCTAGAACAGTATGCAGAGAGTGAGTTTAACAAGGTTCGTAGTTTC
    GCCTTTCCAAATGCTTACTTTGAGAAGGATAACAAGGTCTCTTCGCGTGGGTCTAAAGGG
    GACTTTATCTTCCGTGAGTGTGATGAAAATGGAGTTGAAATCATTTCTATCATGTTTGAG
    ATGAAAAACGAAGCGGACGGAACAGAGAAGAAGCACAAGAATGCAGATTTTTACAAGGAA
    TTGGACAAGGACCGTCGGGAGAAGAACTGTGAGTATGCCGTTTTGGTGACCATGCTTGAG
    GCTGATAATGACTACTTTAACACAGGGATTGTTGACGTCAGTCACGAGTATGAAAAAATG
    TATGTTGTTCGTCCTCAATTCTTTATCCAATTGATTGGTCTCTTACGTAATGCGGCGCTA
    AATTCCCTAAAATACAAGCAGGAGTTGGCCTTGGTTCGCGAGCAAAATATTGACATTACG
    CATTTTGAGGAAGACTTGGATGCCTTTAAGCTAGCTTTTGCTAAGAACTATAATTCAGCT
    TCGACTAACTTTGGAAAAGCTATTGATGAAATCGACAAGGCCATCAAACGCATGGAAGAG
    GTTAAGAAATTCCTGACTACATCTGAAAACCAACTCCGTCTAGCTAACAACAAATTGGAA
    GATGTCTCTGTTAAAAAATTGACCCGGAAAAATCCAACAATGAAAGCGAAGTTCGAAGCA
    TTGAAGGGGGAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1275

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_RS06135 [old locus tag: SPAP_1240 ]
  • symbol: SPAP_RS06135
  • description: DUF2130 domain-containing protein
  • length: 424
  • theoretical pI: 5.0321
  • theoretical MW: 49163
  • GRAVY: -0.805189

⊟Function[edit | edit source]

  • TIGRFAM:
    MJ0042 family finger-like domain (TIGR02098; HMM-score: 14.5)
    Cys-rich peptide, TIGR04165 family (TIGR04165; HMM-score: 13.5)
    and 2 more
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 4.5)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 4.5)
  • TheSEED: see SPAP_1240
  • PFAM:
    no clan defined DUF2130; Uncharacterized protein conserved in bacteria (DUF2130) (PF09903; HMM-score: 276.8)
    and 6 more
    Vps51 (CL0295) Sec8_exocyst; Sec8 exocyst complex component specific domain (PF04048; HMM-score: 18)
    Zn_Beta_Ribbon (CL0167) zinc_ribbon_4; zinc-ribbon domain (PF13717; HMM-score: 14.4)
    zinc_ribbon_5; zinc-ribbon domain (PF13719; HMM-score: 13.4)
    no clan defined PKcGMP_CC; Coiled-coil N-terminus of cGMP-dependent protein kinase (PF16808; HMM-score: 13)
    Zn_Beta_Ribbon (CL0167) zf-ribbon_3; zinc-ribbon domain (PF13248; HMM-score: 11.9)
    no clan defined Fez1; Fez1 (PF06818; HMM-score: 7.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9952
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.0039
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003031
    • TAT(Tat/SPI): 0.000249
    • LIPO(Sec/SPII): 0.000482
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001002635 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQELALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEVQALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQLKAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKLEDVSVKKLTRKNPTMKAKFEALKGE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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