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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_0201 [new locus tag: SPCG_RS01070 ]
  • pan locus tag?: PNEUPAN000917000
  • symbol: uvrA
  • pan gene symbol?: uvrA
  • synonym:
  • product: excinuclease ABC subunit A

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_0201 [new locus tag: SPCG_RS01070 ]
  • symbol: uvrA
  • product: excinuclease ABC subunit A
  • replicon: chromosome
  • strand: +
  • coordinates: 200989..203853
  • length: 2865
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    ATGGTAAGCAATAATGGACTAGAAAGAACAACGATGCAAGATAAAATTGTCATTCATGGG
    GCGCGTGCCCATAACTTTCAATATATTGATGTGGAGATTCCGCGAGACAAGTTGGTTGTC
    GTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGTCTGGCTTTTGATACTCTCTATGCGGAG
    GGACAACGTCGCTATGTAGAGAGTTTGTCCGCCTACGCTCGTCAGTTCTTGGGAAATATG
    GAAAAACCAGATGTAGATGCCATTGATGGTCTCAGCCCAGCTATTTCCATCGACCAGAAA
    ACGACTAGTAAAAATCCTCGCTCGACGGTGGGAACGACGACTGAAATCAATGACTATCTG
    CGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGACATGGAGCTATCAAT
    GCTTCTTCTGTGGAGCAAATCGTTGATAAGGTTTTGGAGTTACCTGAAGGCCAGCGCTTG
    CAGATCTTGGCTCCTGTCATCCGCAAGAAAAAAGGCCAACATAAGAGTGTTATCGAGAAG
    GTTCAGAAAGACGGGTATGTTCGTGTTCGTGTGGATGGGGAAGTCTATGATGTGACCGAA
    GTGCCAGAGTTGTCTAAGAGCAAGCAACACAATATCGATGTCGTGGTTGACCGTATTGTT
    ATCAAGGAGGGCATTCGTAGTCGTCTCTTTGATTCCATTGAGGCTGCCCTTCGTATTGCA
    GAAGGTTATGTCATTATCGACACCATGGACGATTCGGAGTTGCTCTTCTCTGAGCATTAT
    GCCTGTCCAGTTTGTGGTTTTACTGTCCCAGAGTTAGAGCCTCGTCTCTTCTCTTTCAAT
    GCTCCTTTTGGCTCTTGTAGTGAGTGTGACGGCTTGGGCATCAAGCTGGAGGTGGATACT
    GATTTGGTAGTGCCAGATGCCAGCAAAACCTTACGTGAGGGAGCGCTAGCACCTTGGAAT
    CCTATCTCATCCAACTACTATCCAAACATGTTAGAGCAGGCCATGAAAGTCTTTGGAGTG
    GCTATGGATAAGCCTTTTGAGGACCTGTCAGAAGAAGATAAGAACTTGATTCTCTATGGG
    TCAGATGGTAAGGAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATC
    GACATTCCGTTTGAGGGAGTTATCAATAATATCAAACGTCGTTACCATGAAACCAATAGC
    GATTACACTCGCACTCAGATGCGTCTCTACATGAATGAGCTGACCTGCGGAACCTGTCAA
    GGCTATCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTGGGCGGCCAGCAAGGGCCACAT
    ATTGGAGAAATCTCAGACCTGTCTATCGCTGACCACTTGGACTTGGTGAGCCAGTTAACT
    TTGTCTGAAAATGAAGCCATCATTGCTCGTCCCATTCTCAAGGAAATCAAGGATCGTTTG
    ACCTTCCTTAATAATGTGGGTCTTAACTATCTAACCCTGTCACGTTCAGCAGGAACCCTT
    TCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCAACCCAGATTGGTTCCAACCTATCAGGC
    GTCCTCTATATCCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGACAATGACCGCCTG
    ATTGCCAGTCTGAAAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACACGAC
    GAAGATACCATGCGTGAAGCTGATTATCTGATTGACGTTGGTCCTGGTGCCGGTGTTTTT
    GGTGGTGAGATTGTTGCAGCAGGTACACCTAAGCAAGTGGCTCGCAACAGCAAGTCTATC
    ACAGGTCAGTACTTGTCAGGCAAACGTGTCATCCCAGTACCAGAAGAGCGCCGTGTCGGA
    AATGGTCGTTTTATTGAAGTGATAGGAGCGCGTGAGAACAACTTGCAAAATGTCACGGCT
    CGCTTTCCACTAGGAAAATTTATCGCAGTGACAGGTGTGTCGGGTTCAGGGAAATCGACT
    CTAATCAACAGCATTCTCAAAAAAGCCATTGCCCAGAAGCTCAACCGTAATTCAGACAAA
    CCTGGTAAGTTTAAGACTATTACAGGGATTGAGCATGTCGACCGTTTGATTGATATTGAC
    CAGAGCCCTATCGGACGGACGCCGAGGTCTAACCCAGCTACCTATACAGGAGTTTTTGAC
    GATATACGTGACCTTTTTGCTCAGACAAATGAAGCCAAGATTCGAGGCTACAAGAAGGGG
    CGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGTGAAGCTTGCTCAGGTGACGGGATTATC
    AAGATTGAGATGCACTTCTTGCCAGATGTTTATGTGGCTTGTGAAGTTTGCCACGGAACC
    CGCTATAACAGTGAAACCCTAGAAGTTCACTACAAGGAAAAGAATATTTCGCAGGTCTTG
    GATATGACGGTCAACGATGCGGTAGAATTTTTCCAACACATTCCGAAAATTCAACGCAAA
    CTCCAGACCATCAAGGATGTAGGGCTAGGCTATGTGACCTTGGGACAGCCAGCTACCACC
    CTTTCTGGGGGAGAAGCCCAACGTATGAAGTTAGCTAGCGAACTCCACAAACGCTCGACA
    GGAAAATCTTTCTACATTCTGGATGAGCCGACGACAGGGCTTCATACAGAGGACATTGCT
    CGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGACGATGGCAATACAGTCCTCGTCATCGAG
    CACAATCTGGATGTTATCAAGACGGCAGACCATATCATTGACTTGGGACCTGAGGGCGGT
    GTCGGTGGTGGAACCATCATCGTAACAGGAACTCCAGAAGAAGTAGCTGCCAACGAAGCC
    AGCTATACAGGACACTATTTGAAAGGAAAGTTACATCATGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2865

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_0201 [new locus tag: SPCG_RS01070 ]
  • symbol: UvrA
  • description: excinuclease ABC subunit A
  • length: 954
  • theoretical pI: 6.22819
  • theoretical MW: 105372
  • GRAVY: -0.302096

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 1447.5)
    and 100 more
    Cellular processes Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 124.7)
    Metabolism Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 124.7)
    thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 119.6)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 116.7)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 103.4)
    Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 100.2)
    proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 92.6)
    thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 85.7)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 85.5)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 83.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 78.2)
    phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 77.4)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 76.8)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 73.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 72.4)
    Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 72.4)
    ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 71.2)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 70.7)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 70.7)
    Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 69.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 69.2)
    Metabolism Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 68.8)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 68.4)
    Metabolism Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 68.4)
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 68.3)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 67.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 65.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 63.5)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 63.5)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 63.5)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 60.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 60.7)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 59.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 57.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 56.7)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 56.3)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 56.2)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 56.2)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 53.7)
    ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 53.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 53.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 52.8)
    Metabolism Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 52.8)
    D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 52.1)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 51.3)
    Metabolism Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 50.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 49)
    Metabolism Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 47.7)
    Metabolism Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 47.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 45.4)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 45.2)
    Metabolism Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 44.3)
    ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 43.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 42.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 41)
    lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 40)
    Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 35.3)
    ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 34.3)
    Metabolism Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 34.2)
    Cellular processes Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 33.6)
    Metabolism Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 33.6)
    2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 33.2)
    gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 33)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 23.3)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTP-binding protein YsxC (TIGR03598; HMM-score: 22.8)
    Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 20.1)
    Metabolism Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 19.5)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions dTMP kinase (TIGR00041; EC 2.7.4.9; HMM-score: 18.9)
    Dot/Icm secretion system ATPase DotB (TIGR02524; HMM-score: 18.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions guanylate kinase (TIGR03263; EC 2.7.4.8; HMM-score: 18.1)
    HprK-related kinase B (TIGR04355; HMM-score: 18.1)
    Metabolism Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 17.4)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN (TIGR02322; HMM-score: 16.8)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 16.3)
    Metabolism Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 15.8)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exonuclease SbcC (TIGR00618; HMM-score: 14.8)
    Genetic information processing Protein synthesis Other GTP-binding protein Era (TIGR00436; HMM-score: 13.9)
    Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 13.8)
    Cell structure Cell envelope Surface structures twitching motility protein (TIGR01420; HMM-score: 13.8)
    Cellular processes Cellular processes Chemotaxis and motility twitching motility protein (TIGR01420; HMM-score: 13.8)
    Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 13.5)
    Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 13.5)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 13.4)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTP-binding protein YlqF (TIGR03596; HMM-score: 13.4)
    KaiC domain protein, PAE1156 family (TIGR03881; HMM-score: 13.4)
    Cellular processes Cellular processes Pathogenesis type II secretion system protein E (TIGR02533; HMM-score: 13.2)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein E (TIGR02533; HMM-score: 13.2)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein YjeE (TIGR00150; HMM-score: 12.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking putative secretion ATPase, PEP-CTERM locus subfamily (TIGR03015; HMM-score: 12.9)
    Metabolism Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 12.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 12.2)
    Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 12.2)
    carbohydrate kinase, thermoresistant glucokinase family (TIGR01313; EC 2.7.1.-; HMM-score: 12)
    P-type DNA transfer ATPase VirB11 (TIGR02788; HMM-score: 11.9)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTPase YqeH (TIGR03597; HMM-score: 11.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaA regulatory inactivator Hda (TIGR03420; HMM-score: 11.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 10.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 10.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin-guanine dinucleotide biosynthesis protein B (TIGR00176; HMM-score: 10.6)
    Genetic information processing Transcription RNA processing polynucleotide kinase-phosphatase (TIGR04075; HMM-score: 9.8)
  • TheSEED  :
    • Excinuclease ABC subunit A
    DNA Metabolism DNA repair DNA repair, UvrABC system  Excinuclease ABC subunit A
  • PFAM:
    no clan defined UvrA_inter; UvrA interaction domain (PF17760; HMM-score: 136.6)
    UvrA_DNA-bind; UvrA DNA-binding domain (PF17755; HMM-score: 126.4)
    and 43 more
    P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 79.9)
    SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 51.4)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 40)
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 32.6)
    RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 30.3)
    AAA_22; AAA domain (PF13401; HMM-score: 27.7)
    AAA_33; AAA domain (PF13671; HMM-score: 26)
    AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 25.5)
    AAA_18; AAA domain (PF13238; HMM-score: 23.8)
    AAA_23; AAA domain (PF13476; HMM-score: 23.8)
    MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 23.1)
    AAA_25; AAA domain (PF13481; HMM-score: 21.7)
    Viral_helicase1; Viral (Superfamily 1) RNA helicase (PF01443; HMM-score: 21.4)
    AAA_14; AAA domain (PF13173; HMM-score: 21.2)
    APS_kinase; Adenylylsulphate kinase (PF01583; HMM-score: 20.1)
    DUF2075; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 19.6)
    ATPase; KaiC (PF06745; HMM-score: 19.5)
    NACHT; NACHT domain (PF05729; HMM-score: 19.3)
    cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 17.8)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 17.5)
    DUF87; Helicase HerA, central domain (PF01935; HMM-score: 17.3)
    no clan defined DnaJ_CXXCXGXG; DnaJ central domain (PF00684; HMM-score: 16.8)
    P-loop_NTPase (CL0023) AAA_24; AAA domain (PF13479; HMM-score: 16.5)
    no clan defined RACo_linker; RACo linker region (PF17650; HMM-score: 16.5)
    P-loop_NTPase (CL0023) NB-ARC; NB-ARC domain (PF00931; HMM-score: 15.9)
    AAA_30; AAA domain (PF13604; HMM-score: 15.9)
    PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 15)
    Septin; Septin (PF00735; HMM-score: 15)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 15)
    BCA_ABC_TP_C; Branched-chain amino acid ATP-binding cassette transporter (PF12399; HMM-score: 15)
    IIGP; Interferon-inducible GTPase (IIGP) (PF05049; HMM-score: 14.8)
    AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 14.7)
    ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 14.5)
    MeaB; Methylmalonyl Co-A mutase-associated GTPase MeaB (PF03308; HMM-score: 14.3)
    Glutaminase_I (CL0014) DUF4350; Domain of unknown function (DUF4350) (PF14258; HMM-score: 14.3)
    P-loop_NTPase (CL0023) Dynamin_N; Dynamin family (PF00350; HMM-score: 13.9)
    C2H2-zf (CL0361) SF3a60_Prp9_C; SF3a60/Prp9 C-terminal (PF11931; HMM-score: 13.8)
    P-loop_NTPase (CL0023) NTPase_1; NTPase (PF03266; HMM-score: 12.7)
    SbcC_Walker_B; SbcC/RAD50-like, Walker B motif (PF13558; HMM-score: 12.5)
    DUF463; YcjX-like family, DUF463 (PF04317; HMM-score: 12.3)
    AAA_28; AAA domain (PF13521; HMM-score: 12.2)
    Zeta_toxin; Zeta toxin (PF06414; HMM-score: 12.1)
    RING (CL0229) FANCL_C; FANCL C-terminal domain (PF11793; HMM-score: 10.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7919
    • Cytoplasmic Membrane Score: 0.1589
    • Cell wall & surface Score: 0.0023
    • Extracellular Score: 0.0469
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014071
    • TAT(Tat/SPI): 0.006078
    • LIPO(Sec/SPII): 0.001529
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACB89453 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVSNNGLERTTMQDKIVIHGARAHNFQYIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPEGQRLQILAPVIRKKKGQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNLQNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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