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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_0699 [new locus tag: SPCG_RS03650 ]
  • pan locus tag?: PNEUPAN001711000
  • symbol: SPCG_0699
  • pan gene symbol?: livJ
  • synonym:
  • product: branched-chain amino acid ABC transporter, amino acid-binding protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_0699 [new locus tag: SPCG_RS03650 ]
  • symbol: SPCG_0699
  • product: branched-chain amino acid ABC transporter, amino acid-binding protein
  • replicon: chromosome
  • strand: +
  • coordinates: 694813..695973
  • length: 1161
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAGAAAAAATTTGCCTTATCGTTTGTGGCGCTTGCAAGTGTAGCACTTCTTGCAGCC
    TGTGGAGAAGTGAAGTCTGGAGCAGTCAACACTGCTGGTAACTCAGTAGAGGAAAAGACA
    ATTAAAATCGGGTTTAACTTTGAAGAATCAGGTTCTTTAGCTGCATACGGAACAGCTGAA
    CAAAAAGGTGCCCAATTGGCTGTTGATGAAATCAATGCCGCAGGTGGTATCGATGGAAAA
    CAAATCGAAGTAGTCGATAAAGATAATAAGTCTGAAACAGCTGAGGCTGCTTCAGTTACA
    ACTAACCTTGTAACCCAATCTAAAGTATCAGCAGTCGTAGGACCTGCGACATCTGGTGCG
    ACTGCAGCTGCGGTAGCGAACGCTACAAAAGCAGGTGTTCCATTGATCTCACCAAGTGCG
    ACTCAAGATGGATTGACTAAAGGTCAAGATTACCTCTTTATTGGAACTTTCCAAGATAGC
    TTCCAAGGAAAAATTATCTCAAACTATGTTTCTGAAAAATTAAATGCTAAGAAAGTTGTT
    CTTTACACTGACAATGCCAGTGACTATGCTAAAGGGATTGCCAAATCTTTCCGCGAGTCA
    TACAAGGGTGAAATCGTTGCAGATGAAACTTTCGTAGCAGGTGACACAGACTTTCAAGCA
    GCCCTTACAAAAATGAAAGGGAAAGACTTTGATGCTATCGTTGTTCCTGGTTACTATAAT
    GAGGCTGGTAAGATTGTAAACCAAGCGCGTGGCATGGGAATTGACAAACCAATCGTTGGT
    GGTGATGGATTCAACGGTGAGGAGTTTGTACAACAAGCAACTGCTGAAAAAGCATCAAAC
    ATCTACTTTATTTCAGGCTTCTCAACTACTGTAGAAGTTTCAGCTAAAGCTAAAGCCTTC
    CTTGACGCTTACCGTGCTAAGTACAATGAAGAGCCTTCAACATTTGCAGCCTTGGCTTAT
    GATTCAGTTCACCTTGTAGCAAACGCAGCAAAAGGTGCTAAAAATTCAGGTGAAATCAAG
    GATAACCTTGCTAAAACAAAAGATTTTGAAGGTGTAACTGGTCAAACAAGCTTCGATGCA
    GACCACAACACAGTCAAAACTGCTTACATGATGACCATGAACAATGGTAAAGTTGAAGCA
    GCAGAAGTTGTAAAACCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1161

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_0699 [new locus tag: SPCG_RS03650 ]
  • symbol: SPCG_0699
  • description: branched-chain amino acid ABC transporter, amino acid-binding protein
  • length: 386
  • theoretical pI: 4.93857
  • theoretical MW: 40415
  • GRAVY: -0.17772

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, substrate-binding protein (TIGR03669; HMM-score: 73.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, urea binding protein (TIGR03407; HMM-score: 63.3)
  • TheSEED  :
    • High-affinity leucine-specific transport system, periplasmic binding protein LivK (TC 3.A.1.4.1)
    Membrane Transport ABC transporters ABC transporter branched-chain amino acid (TC 3.A.1.4.1)  Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1)
    and 1 more
    Membrane Transport ABC transporters ABC transporter branched-chain amino acid (TC 3.A.1.4.1)  High-affinity leucine-specific transport system, periplasmic binding protein LivK (TC 3.A.1.4.1)
  • PFAM:
    Periplas_BP (CL0144) Peripla_BP_6; Periplasmic binding protein (PF13458; HMM-score: 200.9)
    and 3 more
    ANF_receptor; Receptor family ligand binding region (PF01094; HMM-score: 103.3)
    Peripla_BP_5; Periplasmic binding protein domain (PF13433; HMM-score: 76.6)
    LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 8.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • SignalP: Signal peptide LIPO(Sec/SPII) length 20 aa
    • SP(Sec/SPI): 0.003975
    • TAT(Tat/SPI): 0.000077
    • LIPO(Sec/SPII): 0.995755
    • Cleavage Site: CS pos: 20-21. LAA-CG. Pr: 0.9963
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIGFNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTNLVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDSFQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDFQAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAEKASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAKNSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, CodY (activation (repression)) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 
    CodY(TF)important in Amino acid metabolism; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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