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serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
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A66
serotype 3
AP200
serotype 11A
ASP0581
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ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_0976 [new locus tag: SPCG_RS05075 ]
  • pan locus tag?: PNEUPAN002030000
  • symbol: lmb
  • pan gene symbol?: lmb
  • synonym: adcAII
  • product: adhesion lipoprotein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_0976 [new locus tag: SPCG_RS05075 ]
  • symbol: lmb
  • product: adhesion lipoprotein
  • replicon: chromosome
  • strand: +
  • coordinates: 952154..953089
  • length: 936
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGTTAAGGAGTTGTTCATGAAGAAACAAAATTTATTTTTAGTCCTGTTAAGTGTCTTT
    CTTTTGTGCTTGGGGGCTTGTGGTCAAAAGGAAAGTCAGACAGGAAAGGGGATGAAAATT
    GTGACCAGTTTTTATCCTATCTACGCTATGGTTAAGGAAGTATCTGGTGACTTGAATGAT
    GTTCGGATGATTCAGTCAAGTAGTGGTATTCACTCCTTTGAACCTTCGGCAAATGATATC
    GCAGCCATCTATGATGCAGATGTCTTTGTTTACCATTCTCATACACTCGAATCTTGGGCA
    GGAAGTCTGGATCCAAATCTAAAAAAATCCAAAGTGAAGGTCTTAGAGGCTTCTGAGGGA
    ATGACCTTGGAACGTGTCCCTGGACTAGAGGATGTGGAAGCAGGGGATGGAGTTGATGAA
    AAAACGCTCTATGACCCTCACACATGGCTAGATCCTGAAAAAGCTGGAGAAGAAGCCCAA
    ATTATCGCTGATAAACTTTCAGAGGTGGATAGTGAGCATAAAGAGACTTATCAAAAAAAT
    GCGCAAGCCTTTATCAAAAAAGCTCAGGAATTGACTAAGAAATTCCAACCAAAATTTGAA
    AAAGCGACTCAGAAAACATTTGTAACACAACATACAGCCTTTTCTTATCTAGCGAAGAGA
    TTTGGGCTTAATCAACTTGGTATTGCAGGTATCTCTCCTGAACAAGAACCAAGTCCACGA
    CAACTAACAGAAATTCAGGAATTTGTTAAGACCTATAAGGTTAAAACGATTTTTACAGAA
    AGTAACGCTTCTTCAAAAGTAGCTGAAACTCTTGTCAAATCAACAGGTGTGGGTCTTAAA
    ACTCTGAATCCTTTAGAGTCAGACCCACAAAATGACAAGACCTATTTAGAAAATCTTGAA
    GAAAATATGAGTATTCTAGCAGAAGAATTAAAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    936

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_0976 [new locus tag: SPCG_RS05075 ]
  • symbol: Lmb
  • description: adhesion lipoprotein
  • length: 311
  • theoretical pI: 5.04415
  • theoretical MW: 34699.2
  • GRAVY: -0.401608

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate anchored repeat ABC transporter, substrate-binding protein (TIGR03772; HMM-score: 92.1)
  • TheSEED  :
    • Laminin-binding surface protein
  • PFAM:
    Chelatase (CL0043) ZnuA; Zinc-uptake complex component A periplasmic (PF01297; HMM-score: 227.1)
    and 2 more
    Peptidase_MH (CL0035) SpoIIP; Stage II sporulation protein P (SpoIIP) (PF07454; HMM-score: 14.7)
    LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 9.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.04
    • Cytoplasmic Membrane Score: 9.96
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • SignalP: Signal peptide LIPO(Sec/SPII) length 26 aa
    • SP(Sec/SPI): 0.003867
    • TAT(Tat/SPI): 0.000138
    • LIPO(Sec/SPII): 0.995185
    • Cleavage Site: CS pos: 26-27. LGA-CG. Pr: 0.9890
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVKELFMKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAMVKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLKKSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKLSEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLNQLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTLNPLESDPQNDKTYLENLEENMSILAEELK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: AdcR (repression) regulon
    AdcR(TF)important in Zinc homeostasis; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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