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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_1395 [new locus tag: SPCG_RS07215 ]
  • pan locus tag?: PNEUPAN002682000
  • symbol: SPCG_1395
  • pan gene symbol?: nagD
  • synonym:
  • product: hydrolase, haloacid dehalogenase-like family

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_1395 [new locus tag: SPCG_RS07215 ]
  • symbol: SPCG_1395
  • product: hydrolase, haloacid dehalogenase-like family
  • replicon: chromosome
  • strand: -
  • coordinates: 1380613..1381386
  • length: 774
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAAATATAAAGGCTATTTAATTGATTTAGACGGAACCATTTATAAGGGGAAAGACCGA
    ATCCCTGCTGGAGAGACTTTTGTTCATGAATTGCAAAAGCGGGACATTCCCTATCTCTTT
    GTAACCAACAATACAACCCGCACTCCAGAGAGTGTTAAGGAGATGTTGGCTCAGAATTTT
    AATATCGATACGCCCCTATCGACTGTCTACACAGCGACTTTGGCAACCATCGACTATATG
    AATGATTTGGGGCTTGAAAAGACCGTCTATGTCGTCGGAGAAGCAGGACTCAAGGAAGCC
    ATCAAGGCGGCTGGTTATGTGGAAGACAAGGAAAACCCTGCCTACGTGGTAGTTGGTCTG
    GATTGGCAAGTCGACTATGAAAAATTTGCCACAGCAACTCTTGCTATTCAAAAGGGTGCC
    CATTTTATCGGAACCAATCCTGACCTCAACATCCCGACGGAACGCGGTCTTTTGCCAGGT
    GCTGGCTCACTGATTACGCTGCTTGAAGTAGCGACACGAGTGAAGCCGGTTTATATCGGA
    AAACCCAATGCCATCATTATGGACAAGGCGGTTGAGCACTTAGGTTTGGAACGTGAAGAG
    TTAATCATGGTTGGGGACAATTATTTGACTGATATCCGGGCTGGGATTGACAATGGCATT
    CCAACGCTCTTGGTGACGACAGGTTTTACTAAGGCAGAAGAAGTAGCTGGCCTGCCAATC
    GCACCGACACATGTGGTTTCTAGCCTTGCGGAGTGGGATTTTGATGAAAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    774

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_1395 [new locus tag: SPCG_RS07215 ]
  • symbol: SPCG_1395
  • description: hydrolase, haloacid dehalogenase-like family
  • length: 257
  • theoretical pI: 4.45005
  • theoretical MW: 28208
  • GRAVY: -0.0715953

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01457 family (TIGR01457; HMM-score: 453.2)
    and 19 more
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIA (TIGR01460; HMM-score: 128.2)
    phosphoglycolate/pyridoxal phosphate phosphatase family (TIGR01452; EC 3.1.3.18; HMM-score: 115.2)
    Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01458 family (TIGR01458; HMM-score: 63.3)
    HAD hydrolase, TIGR01459 family (TIGR01459; HMM-score: 55.3)
    noncanonical pyrimidine nucleotidase, YjjG family (TIGR02254; EC 3.1.3.5; HMM-score: 31.3)
    HAD phosphatase, family IIIA (TIGR01668; EC 3.1.3.-; HMM-score: 30.8)
    HAD hydrolase, TIGR02253 family (TIGR02253; HMM-score: 30.6)
    HAD hydrolase, TIGR01456 family (TIGR01456; HMM-score: 27.8)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIIA (TIGR01662; HMM-score: 25.2)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IA, variant 1 (TIGR01549; HMM-score: 22.1)
    HAD hydrolase, REG-2-like, family IA (TIGR02252; HMM-score: 21.8)
    AHBA synthesis associated protein (TIGR01454; HMM-score: 21)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IIB (TIGR01484; HMM-score: 20.8)
    Metabolism Energy metabolism Sugars phosphoglycolate phosphatase, bacterial (TIGR01449; EC 3.1.3.18; HMM-score: 18.6)
    phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 18.5)
    histidinol-phosphate phosphatase domain (TIGR01656; HMM-score: 17.6)
    Unknown function Enzymes of unknown specificity Cof-like hydrolase (TIGR00099; HMM-score: 16.5)
    Genetic information processing Transcription Transcription factors transcription termination factor NusA, C-terminal duplication (TIGR01954; HMM-score: 16.1)
    Unknown function Enzymes of unknown specificity HAD hydrolase, family IA, variant 3 (TIGR01509; HMM-score: 15.2)
  • TheSEED  :
    • Hypothetical NagD-like phosphatase
  • PFAM:
    HAD (CL0137) Hydrolase_like; HAD-hyrolase-like (PF13242; HMM-score: 71.6)
    Hydrolase_6; haloacid dehalogenase-like hydrolase (PF13344; HMM-score: 69.5)
    and 4 more
    HAD_2; haloacid dehalogenase-like hydrolase (PF13419; HMM-score: 35.8)
    Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 33.4)
    MBB (CL0193) DUF6048; Domain of unknown function (DUF6048) (PF19515; HMM-score: 19.4)
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9991
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0005
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009911
    • TAT(Tat/SPI): 0.000233
    • LIPO(Sec/SPII): 0.001491
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACB90647 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNNTTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIKAAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPGAGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDNGIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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