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TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_2012
  • pan locus tag?:
  • symbol: SPCG_2012
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_2012
  • symbol: SPCG_2012
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1996851..1997231
  • length: 381
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001033 (1996851..1997231) NCBI
  • BioCyc:
  • MicrobesOnline: 5761385 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGTTGGAGCAAGCTCGTTTGAAAGTGGAGCAGCAAGCAATCAAGAATATCCAGTTTTTG
    GAGCAAGATTTACCGAAAAATCCCTTGGAGAAAGAGTTTGATTGCCTTGCTGTTAGTCGG
    GTTCTTCATCATATGCCTGATTTGGATGCGGCTCTCTCACTGTTTCATCAACATTTGAAG
    GAAGATGGGAAACTCATCATTGCTGATTTTACCAGGACAGAAGCTAATCATCATGGATTT
    GATTTAGCTGAACTGGAAAACAAGCTAATTGAGCATGGTTTTTCATCTGTGCATAGTCAG
    ATTCTCTATAGTGCTGAAGACCTGTTTCAAGGAAATCACTCAGAATTCTTTTTAATAGTA
    GCCCAAAAATCACTCGCCTAG
    60
    120
    180
    240
    300
    360
    381

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_2012
  • symbol: SPCG_2012
  • description: hypothetical protein
  • length: 126
  • theoretical pI: 5.45253
  • theoretical MW: 14431.3
  • GRAVY: -0.253968

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone ubiquinone/menaquinone biosynthesis methyltransferase (TIGR01934; EC 2.1.1.-; HMM-score: 27.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin malonyl-acyl carrier protein O-methyltransferase BioC (TIGR02072; EC 2.1.1.-; HMM-score: 26.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 3-demethylubiquinone-9 3-O-methyltransferase (TIGR01983; EC 2.1.1.64; HMM-score: 25.6)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs putative 4-mercaptohistidine N1-methyltranferase (TIGR04345; HMM-score: 12.6)
    Metabolism Transport and binding proteins Cations and iron carrying compounds (2,3-dihydroxybenzoyl)adenylate synthase (TIGR02275; EC 2.7.7.58; HMM-score: 10.7)
  • TheSEED  :
    • Methylase involved in ubiquinone/menaquinone biosynthesis
  • PFAM:
    NADP_Rossmann (CL0063) Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 35.8)
    Methyltransf_11; Methyltransferase domain (PF08241; HMM-score: 34.2)
    Methyltransf_12; Methyltransferase domain (PF08242; HMM-score: 31.9)
    Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 31.1)
    Methyltransf_23; Methyltransferase domain (PF13489; HMM-score: 30.4)
    and 6 more
    Ubie_methyltran; ubiE/COQ5 methyltransferase family (PF01209; HMM-score: 27.5)
    NodS; Nodulation protein S (NodS) (PF05401; HMM-score: 16.9)
    CheR; CheR methyltransferase, SAM binding domain (PF01739; HMM-score: 16)
    Bmt2; 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 (PF11968; HMM-score: 13.9)
    PDDEXK (CL0236) RE_TaqI; TaqI restriction endonuclease (PF09573; HMM-score: 13.3)
    NADP_Rossmann (CL0063) NNMT_PNMT_TEMT; NNMT/PNMT/TEMT family (PF01234; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000726
    • TAT(Tat/SPI): 0.000075
    • LIPO(Sec/SPII): 0.000103
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEFDCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTRTEANHHGFDLAELENKLIEHGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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