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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_2135 [new locus tag: SPCG_RS11290 ]
  • pan locus tag?: PNEUPAN003826000
  • symbol: fucK
  • pan gene symbol?: fucK
  • synonym:
  • product: L-fuculose kinase fucK, putative

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_2135 [new locus tag: SPCG_RS11290 ]
  • symbol: fucK
  • product: L-fuculose kinase fucK, putative
  • replicon: chromosome
  • strand: -
  • coordinates: 2133069..2134517
  • length: 1449
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    GTGGGGATTATAATAAAGTTAATCAAGGACGAAGAGAGAAGAAAAATGGAAGCGGTTTTA
    GCAATAGATTTAGGTGCGACTTCTGGAAGAGCAATCGTTGGTTACCTTTCTGAAAATAAA
    CTAGTAATGGAAGAAATAAATCGCTTTTCTAATCTACCTATTAGAGTAAAAGGGCATTTA
    TCTTGGGATATTGACTTTCTACTAGCTAAAATTCTTGAAAGTATCCGCTTGGCTAATACT
    AGTTACAAGATTTTATCTATCGGTATTGACACATGGGGAGTTGATTTTGGACTGGTTGAT
    AATGAAGGTAAGCTGTTATTACAACCTGTTCATTATCGTGATGAAAGAACAAAGGGAGTG
    TTAAAGGAAATATCTGAAATGACTGAATTAGAAAAACTGTATTCAGAGACAGGAAATCAG
    ATTATGGAGATAAATACCTTGTTTCAACTCTTTAAGGCACGTCAAGAATCTCCTGACTCT
    TTCTATAAGACCAATAAGATTCTTTTAATGCCAGATTTGTTTAATTATCTCTTGACAGGT
    AAGTTTGCTACAGAAAAAAGCATTGCTTCAACAACTCAATTATTTGATCCTAGGAGTCAA
    AACTGGAATCAGAATATCTTAAAACTATTTGAATTGGATTCATCTTTACTTCCTGAGATT
    GTTTCAGAGGGAAATGTTCTTGGAAGGATAAAAAAGGAGTATGGTTTAGGCGATATTCCT
    GTTGTGAATGTTTGTAGTCATGATACAGCAAGCGCGATTGTCTCAGTACCTAAGACAGAA
    GGTAGTTTATTTATTTCATCAGGTACTTGGTCTTTGGTTGGAGTGGAACTTACTTCACCG
    CTTCTTACTACCGAATCCTTCAGTTATGGATTTACAAATGAAGTCGGTAAAGATGGAGTG
    ATTACATTTCTGAAGAATTGTACAGGGTTGTGGATCATAGAGGAACTAAGACGTTCATTT
    GAACGAAGAGGGAAAGCCTATTCTTTTGATGATATTAGGACAATGGTGGAGAAAGAAAAA
    GAAAATCTTCCTCTGATTGATACTGAATCAACTGAATTTGCAACAGAATCTGATATGCAC
    AAGACTTTGACAGAATATCTAGCTTATCATCATGAAACTAGAGAGTGGACAGATGGACAA
    CTATTTAAGATTGTTTATGAAAGCCTAGCTGAAACGTATAGGAAAGCGATAGAGTTACTA
    GAAGAACTAACTCATAAGGTTTATAAGAGGATATATGTGATTGGAGGAGGTGCTAGAGCC
    AGTTACTTTAACCAAATGATTGCTGATAGAACTGGTAAAGAGGTTCTTACAGGTTTGACT
    GAGGGTACAGCTGTGGGGAATATTGTTGTGCAGCTATTGAGTCAAGGTAAAATAAACGAG
    GATACAGAGTTAAAGGATATTATGACAAATATTGCTGAGACACAATATTATTATCCTCAG
    CTATCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1449

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_2135 [new locus tag: SPCG_RS11290 ]
  • symbol: FucK
  • description: L-fuculose kinase fucK, putative
  • length: 482
  • theoretical pI: 4.86666
  • theoretical MW: 54670.1
  • GRAVY: -0.217012

⊟Function[edit | edit source]

  • TIGRFAM:
    rhamnulokinase (TIGR02627; EC 2.7.1.5; HMM-score: 412.9)
    and 4 more
    Metabolism Energy metabolism Sugars L-fuculokinase (TIGR02628; EC 2.7.1.51; HMM-score: 161.6)
    Metabolism Energy metabolism Sugars xylulokinase (TIGR01312; EC 2.7.1.17; HMM-score: 123)
    Metabolism Energy metabolism Other glycerol kinase (TIGR01311; EC 2.7.1.30; HMM-score: 67.1)
    Metabolism Energy metabolism Sugars gluconate kinase (TIGR01314; EC 2.7.1.12; HMM-score: 57.4)
  • TheSEED  :
    • L-fuculokinase (EC 2.7.1.51)
  • PFAM:
    Actin_ATPase (CL0108) FGGY_N; FGGY family of carbohydrate kinases, N-terminal domain (PF00370; HMM-score: 120.6)
    and 1 more
    FGGY_C; FGGY family of carbohydrate kinases, C-terminal domain (PF02782; HMM-score: 66.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005468
    • TAT(Tat/SPI): 0.001754
    • LIPO(Sec/SPII): 0.001333
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACB91387 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGIIIKLIKDEERRKMEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGHLSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLVDNEGKLLLQPVHYRDERTKGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFNYLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKEYGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGFTNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTESTEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKVYKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLLSQGKINEDTELKDIMTNIAETQYYYPQLS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, FucR* (repression) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 
    FucR*(TF)important in Fucose utilization; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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