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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 24-JAN-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae CGSP14
- locus tag: SPCG_RS00070 [old locus tag: SPCG_0013 ]
- pan locus tag?: PNEUPAN000297000
- symbol: SPCG_RS00070
- pan gene symbol?: comX1
- synonym:
- product: sigma-70 family RNA polymerase sigma factor
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPCG_RS00070 [old locus tag: SPCG_0013 ]
- symbol: SPCG_RS00070
- product: sigma-70 family RNA polymerase sigma factor
- replicon: chromosome
- strand: +
- coordinates: 14450..14929
- length: 480
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_010582 (14450..14929) NCBI
- BioCyc: SPCG_RS00070 BioCyc
- MicrobesOnline: see SPCG_0013
- PneumoBrowse for strain D39V: SPV_0014 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATAT
TACCTTCATTTATGGGAATTATCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAA
TTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCACGTTTAAGGAAATATTTCAAA
ACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGGGGT
CTCTGGCTAGATGATTATTATCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAA
AGTAAAGAGAAACAAGAAGAACTAGAACGTGTCTTAAGCAATGAACGATTTCGAGGGCGT
CAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG60
120
180
240
300
360
420
480
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPCG_RS00070 [old locus tag: SPCG_0013 ]
- symbol: SPCG_RS00070
- description: sigma-70 family RNA polymerase sigma factor
- length: 159
- theoretical pI: 7.61287
- theoretical MW: 19873.4
- GRAVY: -1.08302
⊟Function[edit | edit source]
- TIGRFAM: RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 31.8)and 1 moreRNA polymerase sigma-70 factor, Bacteroides expansion family 1 (TIGR02985; HMM-score: 13.3)
- TheSEED: see SPCG_0013
- PFAM: HTH (CL0123) Sigma70_r2; Sigma-70 region 2 (PF04542; HMM-score: 15.7)
⊟Structure, modifications & cofactors[edit | edit source]
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003025
- TAT(Tat/SPI): 0.000204
- LIPO(Sec/SPII): 0.000824
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0014 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
M S Lee, D A Morrison
Identification of a new regulator in Streptococcus pneumoniae linking quorum sensing to competence for genetic transformation.
J Bacteriol: 1999, 181(16);5004-16
[PubMed:10438773] [WorldCat.org] [DOI] (P p)