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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-JAN-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_RS11250 [old locus tag: SPCG_2127 ]
  • pan locus tag?: PNEUPAN003816000
  • symbol: SPCG_RS11250
  • pan gene symbol?: fucA
  • synonym:
  • product: class II aldolase/adducin family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_RS11250 [old locus tag: SPCG_2127 ]
  • symbol: SPCG_RS11250
  • product: class II aldolase/adducin family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2120688..2121416
  • length: 729
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010582 (2120688..2121416) NCBI
  • BioCyc: SPCG_RS11250 BioCyc
  • MicrobesOnline: see SPCG_2127
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGTCTCAAGATGAAAAATTAATTCGTGAACAGATTTGTGATGTTTGTCATAAGATGTGG
    CAACTTGGTTGGGTTGCTGCTAACGATGGGAATGTATCTGTTCGATTAGATGAGGATACC
    ATTCTTGCAACACCTACTGGTATCAGCAAAAGTTTTATTACACCAGAAAAGCTGGTGAAG
    TTAAATCTCAAAGGAGAGATTTTAGAAGCAGAAGGTGATTACCGGCCCTCTAGTGAAATT
    AAAATGCACATTCGTTGTTACGAAGAACGTGAGGATGTCCGTTCAGTTGTTCACGCGCAT
    CCACCGATTGCAACAGGATTTGCTCTTGCACACATTCCTTTAGATACTTATTCACTAATT
    GAGAGCGCGATTGTGGTAGGGGCAATTCCTATAACGCCATTTGGAGTTCCGTCTACAATG
    GAAGTGCCAGAAGCAATTACACCTTATCTGCCCGATCATGATGTCATGCTATTAGAAAAT
    CATGGAGCTCTGACTGTCGGAAGCGATGTAATTACAGCATACTACCGTATGGAAACTTTA
    GAATTAGTCGCAAAGACAACCTTCCACGGAAGAATGTTACTTTCTACAAAGGGCATTGAG
    GAGCAAGAAATTGCTCGTCCGACTTTAGAACGTCTATTCTCAATGCGAGAAAATTATAAG
    GTTACAGGTCGTCACCCAGGCTACCGTAAATATAATGGCGATGGTAGTATGAAAGAAACA
    GAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    729

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_RS11250 [old locus tag: SPCG_2127 ]
  • symbol: SPCG_RS11250
  • description: class II aldolase/adducin family protein
  • length: 242
  • theoretical pI: 5.3718
  • theoretical MW: 27169
  • GRAVY: -0.278099

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Sugars L-fuculose phosphate aldolase (TIGR01086; EC 4.1.2.17; HMM-score: 80.6)
    Metabolism Amino acid biosynthesis Aspartate family methylthioribulose-1-phosphate dehydratase (TIGR03328; EC 4.2.-.-; HMM-score: 76.4)
    and 4 more
    Metabolism Energy metabolism Sugars L-ribulose-5-phosphate 4-epimerase (TIGR00760; EC 5.1.3.4; HMM-score: 49.1)
    rhamnulose-1-phosphate aldolase (TIGR02624; EC 4.1.2.19; HMM-score: 38.4)
    Cellular processes Cellular processes Biosynthesis of natural products fluorothreonine transaldolase (TIGR04506; EC 2.2.1.8; HMM-score: 18.6)
    tyrosine/nicotianamine family aminotransferase (TIGR01265; HMM-score: 11.5)
  • TheSEED: see SPCG_2127
  • PFAM:
    no clan defined Aldolase_II; Class II Aldolase and Adducin N-terminal domain (PF00596; HMM-score: 151.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006584
    • TAT(Tat/SPI): 0.000269
    • LIPO(Sec/SPII): 0.001188
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILATPTGISKSFITPEKLVKLNLKGEILEAEGDYRPSSEIKMHIRCYEEREDVRSVVHAHPPIATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLENHGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMRENYKVTGRHPGYRKYNGDGSMKETEK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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