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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-MAY-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_0617 [new locus tag: SPD_RS03320 ]
  • pan locus tag?: PNEUPAN001656000
  • symbol: SPD_0617
  • pan gene symbol?: glnP3b
  • synonym:
  • product: amino acid ABC transporter, permease protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_0617 [new locus tag: SPD_RS03320 ]
  • symbol: SPD_0617
  • product: amino acid ABC transporter, permease protein
  • replicon: chromosome
  • strand: -
  • coordinates: 638576..639253
  • length: 678
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGCAGGATTCGGGAATCCAAGTACTCTTTCAAGGAAATAATCTCCTGAGAATCTTACAG
    GGGTTGGGCGTTACGATTGGGATATCCATCCTGTCTGTCCTCTTATCCATGATGTTCGGA
    ACAGTCATGGGAATCATCATGACCTCCCATTCTAGAATCATACGATTTTTAACACGATTG
    TATCTGGAATTTATCCGTATCATGCCCCAGCTGGTGCTACTCTTCATCGTTTACTTTGGC
    TTGGCTCGAAACTTTAATATCAATATCTCAGGTGAGACTTCAGCTATTATCGTTTTTACC
    CTCTGGGGAACAGCTGAAATGGGAGACTTGGTACGTGGAGCTATCACTTCTCTCCCTAAA
    CATCAGTTTGAAAGTGGACAGGCACTCGGCTTGACTAATGTTCAACTTTACTACCACATC
    ATCATCCCACAAGTCTTAAGAAGACTGCTACCGCAGGCTATCAATCTTGTCACTCGGATG
    ATTAAAACCACTTCATTAGTTGTTTTGATTGGGGTTGTGGAAGTGACCAAAGTTGGACAA
    CAAATCATCGATAGCAATCGCCTGACCATCCCAACTGCTTCATTTTGGATTTATGGAACC
    ATTCTAGTCTTATATTTCGCAGTTTGCTACCCTATTTCCAAACTATCCACTCACTTAGAA
    AAACATTGGAGAAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    678

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_0617 [new locus tag: SPD_RS03320 ]
  • symbol: SPD_0617
  • description: amino acid ABC transporter, permease protein
  • length: 225
  • theoretical pI: 10.3754
  • theoretical MW: 25308
  • GRAVY: 0.658667

⊟Function[edit | edit source]

  • TIGRFAM:
    ectoine/hydroxyectoine ABC transporter, permease protein EhuC (TIGR03004; HMM-score: 108.2)
    and 4 more
    ectoine/hydroxyectoine ABC transporter, permease protein EhuD (TIGR03003; HMM-score: 86.2)
    Metabolism Transport and binding proteins Amino acids, peptides and amines amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family (TIGR01726; HMM-score: 72.4)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 40.4)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 14.8)
  • TheSEED  :
    • ABC transporter, permease protein (cluster 3, basic aa/glutamine/opines)
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 53.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001964
    • TAT(Tat/SPI): 0.001748
    • LIPO(Sec/SPII): 0.002637
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CmbR* (activation (repression)) regulon, CodY (activation (repression)) regulon
    CmbR*(TF)important in Cysteine metabolism; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    CodY(TF)important in Amino acid metabolism; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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