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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-MAY-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_1780 [new locus tag: SPD_RS09480 ]
  • pan locus tag?: PNEUPAN003570000
  • symbol: rpe
  • pan gene symbol?: rpe
  • synonym:
  • product: ribulose-phosphate 3-epimerase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_1780 [new locus tag: SPD_RS09480 ]
  • symbol: rpe
  • product: ribulose-phosphate 3-epimerase
  • replicon: chromosome
  • strand: -
  • coordinates: 1776270..1776926
  • length: 657
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTCTCAATACAAGATTGCTCCGTCAATTCTGGCAGCAGATTATGCCAACTTTGAACGT
    GAAATCAAACGTCTAGAAGCAACTGGGGCAGAATATGCCCATATCGATATCATGGACAGT
    CATTTTGTACCGCAAATCAGTTTTGGTGCAGGTGTGGTCGAGAGCCTTCGTCCTCATAGT
    AAGATGGTTTTCGATTGCCACTTGATGGTGTCAAACCCTGAGCATCATCTGGAAGATTTT
    GCGCGTGCAGGTGCAGACATCATCAGTATCCATGTAGAAGCAACACCTCATATTCATGGC
    GCCCTCCAAAAAATTCGTTCACTCGGAGTTAAGCCTTCAGTCGTTATCAATCCTGGCACA
    CCAGTTGAAGCCATCAAGCACGTCCTTCATCTAGTTGACCAAGTTTTAGTCATGACGGTT
    AATCCAGGTTTTGGTGGGCAAGCCTTTCTGCCAGAAACCATGGATAAGGTTCGTGAGTTG
    GTTGCTCTTCGTGAGGAAAAAGGTTTGAACTTTGAAATCGAAGTGGATGGTGGGATTGAT
    GACCAAACTATTGCTCAAGCCAAAGAAGCTGGTGCGACTGTTTTTGTAGCAGGTTCCTAT
    GTCTTTAAGGGAGAAGTCAATGAGCGAGTACAAACTCTCAGAAAACAACTGGACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    657

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_1780 [new locus tag: SPD_RS09480 ]
  • symbol: Rpe
  • description: ribulose-phosphate 3-epimerase
  • length: 218
  • theoretical pI: 5.72871
  • theoretical MW: 23944.2
  • GRAVY: -0.0412844

⊟Function[edit | edit source]

  • reaction:
    EC 5.1.3.1?  ExPASy
    Ribulose-phosphate 3-epimerase D-ribulose 5-phosphate = D-xylulose 5-phosphate
  • TIGRFAM:
    Metabolism Energy metabolism Pentose phosphate pathway ribulose-phosphate 3-epimerase (TIGR01163; EC 5.1.3.1; HMM-score: 273.3)
    and 3 more
    3-hexulose-6-phosphate synthase (TIGR03128; EC 4.1.2.43; HMM-score: 27.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides nicotinate-nucleotide diphosphorylase (carboxylating) (TIGR00078; EC 2.4.2.19; HMM-score: 17.4)
    Unknown function General modD protein (TIGR01334; HMM-score: 12.6)
  • TheSEED  :
    • Ribulose-phosphate 3-epimerase (EC 5.1.3.1)
    Carbohydrates Central carbohydrate metabolism Pentose phosphate pathway  Ribulose-phosphate 3-epimerase (EC 5.1.3.1)
    and 2 more
    Carbohydrates One-carbon Metabolism Formaldehyde assimilation: Ribulose monophosphate pathway  Ribulose-phosphate 3-epimerase (EC 5.1.3.1)
    DNA Metabolism DNA repair 2-phosphoglycolate salvage  Ribulose-phosphate 3-epimerase (EC 5.1.3.1)
  • PFAM:
    TIM_barrel (CL0036) Ribul_P_3_epim; Ribulose-phosphate 3 epimerase family (PF00834; HMM-score: 255.6)
    and 3 more
    QRPTase_C; Quinolinate phosphoribosyl transferase, C-terminal domain (PF01729; HMM-score: 20.2)
    Radical_SAM; Radical SAM superfamily (PF04055; HMM-score: 14.9)
    no clan defined BKACE; beta-keto acid cleavage enzyme (PF05853; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007228
    • TAT(Tat/SPI): 0.000462
    • LIPO(Sec/SPII): 0.000593
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVPQISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGALQKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVRELVALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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