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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 02-FEB-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae D39
- locus tag: SPD_RS02470 [old locus tag: SPD_0459 ]
- pan locus tag?: PNEUPAN001403000
- symbol: grpE
- pan gene symbol?: grpE
- synonym:
- product: nucleotide exchange factor GrpE
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPD_RS02470 [old locus tag: SPD_0459 ]
- symbol: grpE
- product: nucleotide exchange factor GrpE
- replicon: chromosome
- strand: +
- coordinates: 468585..469109
- length: 525
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_008533 (468585..469109) NCBI
- BioCyc: G1G6V-508 BioCyc
- MicrobesOnline: see SPD_0459
- PneumoBrowse for strain D39V: SPV_0459 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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241
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421
481ATGGCCCAAGATATAAAAAATGAAGAAGTAGAAGAAGTTCAAGAAGAGGAAGTTGTGGAA
ACAGCTGAAGAAACAACTCCTGAAAAGTCTGAGTTGGACTTGGCAAATGAACGTGCAGAT
GAGTTCGAAAACAAATATCTTCGCGCTCATGCAGAAATGCAAAATATCCAACGCCGTGCC
AATGAAGAACGTCAAAACTTGCAACGTTATCGTAGCCAGGACTTGGCAAAAGCAATCTTA
CCATCTCTTGACAACCTTGAGCGTGCACTTGCAGTTGAAGGTTTGACAGATGATGTGAAG
AAGGGCTTGGCGATGGTGCAAGAAAGCTTGATTCACGCTTTGAAAGAAGAAGGAATTGAA
GAAATCGCAGCAGATGGCGAATTTGACCATAACTACCATATGGCCATCCAAACTCTCCCA
GGAGACGATGAACACCCAGTAGATACCATCGCCCAAGTCTTTCAAAAAGGCTACAAACTC
CATGACCGCATCCTACGCCCAGCAATGGTAGTGGTGTATAACTAA60
120
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525
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPD_RS02470 [old locus tag: SPD_0459 ]
- symbol: GrpE
- description: nucleotide exchange factor GrpE
- length: 174
- theoretical pI: 4.26627
- theoretical MW: 19969
- GRAVY: -0.756322
⊟Function[edit | edit source]
- TIGRFAM: TraF-like protein (TIGR02740; HMM-score: 6.6)
- TheSEED: see SPD_0459
- PFAM: no clan defined GrpE; GrpE (PF01025; HMM-score: 148.3)and 2 moreGlyco_hydro_tim (CL0058) Glyco_hydro_17; Glycosyl hydrolases family 17 (PF00332; HMM-score: 15.4)no clan defined DUF763; Protein of unknown function (DUF763) (PF05559; HMM-score: 11.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.004548
- TAT(Tat/SPI): 0.026037
- LIPO(Sec/SPII): 0.001268
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFENKYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKGLAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPGDDEHPVDTIAQVFQKGYKLHDRILRPAMVVVYN
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: hrcA > grpE > dnaK > SPD_RS02480 > dnaJ
⊟Regulation[edit | edit source]
- regulator: HrcA see SPD_0459
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0459 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.