From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 21-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39
  • locus tag: SPD_RS05080 [old locus tag: SPD_0944 ]
  • pan locus tag?: PNEUPAN002194000
  • symbol: SPD_RS05080
  • pan gene symbol?: dapH_2
  • synonym:
  • product: acyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPD_RS05080 [old locus tag: SPD_0944 ]
  • symbol: SPD_RS05080
  • product: acyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 954066..955172
  • length: 1107
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGAATCAAAAATTTCAATTTTAGATAGACTATATTCATGGATTTATATTAAGAAATTA
    AAAAAACTAGGTGCAATTATAGAAGAGAATGTTGTGATTTGCTTTGGTGCAAAGCTTTTT
    TTCAATGAAGAATGCTTAATTCAGAAGGATACGGTCATCGGTAGATTTGTACTAATAGAA
    GCAAATAGGATAACAATTGGGAATAATTGCTTATTTTTCCCACGAACTTTAATTTATTCC
    AAGGAAACATTTAGTTTGGGAACACGAGGAAAAATTAGTAAAGATTGTATATTTAGGGCG
    AATAAAATAAATATTGGAAGAGAATTTTGGTGCAATGAGGCAGTAAGAATTGGAGAAGGC
    GGTTGGAATCAAAAAAGTGCAAATATTAAAATTGGTGATTATCAATTCATAGGACCACGA
    GCTCAAATTAATGTAAGTGATTCTGTGGAACTCATGGGATATGGTGGTCTAGGAATCGAG
    ACGATGATCTTTACGCATGGTGCGGGACATGGCCAATCAGCAACTGATGGATTTTATGCT
    GAACAAAATAAAGTTATTATTCAAAAAAATGTCTCAATTTTAACAAGAGCTATTATTCTA
    CCAGGTGTTATAGTCAGTCAAGGCACCACTGTAGCGGCAAATGCTATCGTAACCAAGAGT
    TTTCCAAAGCACTCGTTAATAGGAGGAGTACCGGCTAGGTATATTGGTCAGAGTAATAAA
    GAAATTTCTGTGAAAGAGCAAAAAAATATTATTGTTGACATATTAAAAGAAGGATTAGGA
    ACAGAACCAGTGATAAAAAACAATAGCTTTTGTTTTGAGAAATTTAATGAAAATATTACT
    TTTCAATATGATTTAGAAAAAATTGAATCAACAGACAATATTAGTCAAAGAGATATTATT
    ATATTTTATCAAGGTACAAATAAATGTCATAAAAATTATAGCACCTGTATTGATTTGAAG
    TCTAAAACAATTTCAGGTAGAGCAAGTAAGGCTTCAGAATTTTTAAGAGATAAATTTAGA
    AGAAAAGGAATAATCTTAAATTATAAAAATTATAGTCCATTTTCATTGAATTATGATTAT
    TTAATAATTAATAAGATTGAAGTTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1107

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPD_RS05080 [old locus tag: SPD_0944 ]
  • symbol: SPD_RS05080
  • description: acyltransferase
  • length: 368
  • theoretical pI: 9.54142
  • theoretical MW: 41501.7
  • GRAVY: -0.134239

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.-.-?  ExPASy
  • TIGRFAM:
    2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (TIGR03532; EC 2.3.1.89; HMM-score: 41.2)
    sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family (TIGR03570; HMM-score: 40)
    phosphonate metabolim protein, transferase hexapeptide repeat family (TIGR03308; HMM-score: 37.3)
    colanic acid biosynthesis acetyltransferase WcaF (TIGR04008; EC 2.3.1.-; HMM-score: 36.4)
    and 8 more
    Metabolism Amino acid biosynthesis Serine family serine O-acetyltransferase (TIGR01172; EC 2.3.1.30; HMM-score: 26.5)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (TIGR01853; EC 2.3.1.191; HMM-score: 24.8)
    Metabolism Energy metabolism Other phenylacetic acid degradation protein PaaY (TIGR02287; HMM-score: 21.3)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase (TIGR01852; EC 2.3.1.129; HMM-score: 18.1)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 16.4)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 16.4)
    Metabolism Central intermediary metabolism Amino sugars UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 16.4)
    colanic acid biosynthesis acetyltransferase WcaB (TIGR04016; EC 2.3.1.-; HMM-score: 13.4)
  • TheSEED: see SPD_0944
  • PFAM:
    HEXAPEP (CL0536) Hexapep; Bacterial transferase hexapeptide (six repeats) (PF00132; HMM-score: 24.9)
    and 3 more
    no clan defined DUF5680; Domain of unknown function (DUF5680) (PF18931; HMM-score: 13.4)
    HEXAPEP (CL0536) Hexapep_2; Hexapeptide repeat of succinyl-transferase (PF14602; HMM-score: 10.9)
    no clan defined DUF643; Protein of unknown function (DUF643) (PF04867; HMM-score: 10)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7784
    • Cytoplasmic Membrane Score: 0.1219
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0994
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002908
    • TAT(Tat/SPI): 0.000162
    • LIPO(Sec/SPII): 0.000365
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MESKISILDRLYSWIYIKKLKKLGAIIEENVVICFGAKLFFNEECLIQKDTVIGRFVLIEANRITIGNNCLFFPRTLIYSKETFSLGTRGKISKDCIFRANKINIGREFWCNEAVRIGEGGWNQKSANIKIGDYQFIGPRAQINVSDSVELMGYGGLGIETMIFTHGAGHGQSATDGFYAEQNKVIIQKNVSILTRAIILPGVIVSQGTTVAANAIVTKSFPKHSLIGGVPARYIGQSNKEISVKEQKNIIVDILKEGLGTEPVIKNNSFCFEKFNENITFQYDLEKIESTDNISQRDIIIFYQGTNKCHKNYSTCIDLKSKTISGRASKASEFLRDKFRRKGIILNYKNYSPFSLNYDYLIINKIEV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPD_RS05080&oldid=5470"