From PneumoWiki
Jump to navigation Jump to search
TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_0622
  • pan locus tag?:
  • symbol: SPG_0622
  • pan gene symbol?: —
  • synonym:
  • product: elongation factor Tu family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_0622
  • symbol: SPG_0622
  • product: elongation factor Tu family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 614990..615796
  • length: 807
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001015 (614990..615796) NCBI
  • BioCyc:
  • MicrobesOnline: 5755891 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGACAAAATTAAGAGAAGATATCCGTAACATTGCGATTATCGCCCACGTTGACCACGGT
    AAAACAACCCTCGTTGACGAATTATTGAAACAATCAGAAACGCTTGATGCACGTACTGAA
    TTGGCAGAGCGTGCTATGGACTCAAACGATATCGAAAAAGAGCGTGGGATTACCATCCTT
    GCTAAAAATACTGCCGTTGCTTACAACGGAACTCGTATCAACATTATGGACACACCAGGA
    CACGCGGACTTTGGTGGAGAAGTTGAGCGTATCATGAAAATGGTTGACGGTGTTGTCTTG
    GTCGTAGATGCCTATGAAGGAACCATGCCACAAACTCGTTTCGTATTGAAAAAAGCCTTG
    GAACAAGACCTTGTCCCAATCGTGGTTGTTAACAAAATCGATAAGCCATCAGCTCGTCCA
    GTAGAAGTAGTGGATGAAGTCTTGGAACTTTTCATCGAGCTTGGTGCAGATGACGACCAG
    CTTGATTTCCCAGTGGTTTATGCTTCAGCGATCAACGGAACTTCTTCATTGTCAGATGAT
    CCAGCTGACCAAGAAGCGACTATGGCACCAATCTTTGACACGATTATCGACCATATCCCA
    GCTCCAGTAGATAACTCAGATGAGCCTTTGCAGTTCCAAGTGTCGCTTTTGGACTACAAT
    GACTTCGTTGGACGTATCGGTATCGGTCGTGTCTTCCGTGGTACAGTTAAGGTTGGGGAC
    CAAGTTACCCTTTCTAAACTTGACGGTACAACTAAAAACTTCCGTGTTACAAAACTNCTT
    CGGTTTCTTTGGTTTGGAACGTCGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    807

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_0622
  • symbol: SPG_0622
  • description: elongation factor Tu family protein
  • length: 268
  • theoretical pI: 4.37661
  • theoretical MW: 29630.5
  • GRAVY: -0.101119

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions GTP-binding protein TypA/BipA (TIGR01394; HMM-score: 426.2)
    Genetic information processing Protein synthesis Translation factors GTP-binding protein TypA/BipA (TIGR01394; HMM-score: 426.2)
    Signal transduction Regulatory functions Other GTP-binding protein TypA/BipA (TIGR01394; HMM-score: 426.2)
    and 21 more
    Unknown function General elongation factor 4 (TIGR01393; EC 3.6.5.-; HMM-score: 167.4)
    Genetic information processing Protein synthesis Translation factors translation elongation factor aEF-2 (TIGR00490; HMM-score: 136.2)
    Genetic information processing Protein synthesis Translation factors translation elongation factor G (TIGR00484; HMM-score: 129.7)
    Genetic information processing Protein synthesis Translation factors translation elongation factor Tu (TIGR00485; HMM-score: 97.1)
    Genetic information processing Protein synthesis Translation factors peptide chain release factor 3 (TIGR00503; HMM-score: 87.6)
    Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 84.6)
    Genetic information processing Protein synthesis Translation factors translation elongation factor EF-1, subunit alpha (TIGR00483; HMM-score: 73.3)
    Genetic information processing Protein synthesis Translation factors selenocysteine-specific translation elongation factor (TIGR00475; HMM-score: 68.1)
    Genetic information processing Protein synthesis Translation factors translation initiation factor IF-2 (TIGR00487; HMM-score: 67)
    Metabolism Central intermediary metabolism Sulfur metabolism sulfate adenylyltransferase, large subunit (TIGR02034; EC 2.7.7.4; HMM-score: 47)
    Genetic information processing Protein synthesis Translation factors translation initiation factor aIF-2 (TIGR00491; HMM-score: 41)
    translation initiation factor 2, gamma subunit (TIGR03680; HMM-score: 35.4)
    Genetic information processing Protein synthesis Other ribosome-associated GTPase EngA (TIGR03594; HMM-score: 27.2)
    Genetic information processing Protein fate Protein modification and repair [FeFe] hydrogenase H-cluster maturation GTPase HydF (TIGR03918; HMM-score: 16.8)
    Genetic information processing Protein synthesis Other GTP-binding protein Era (TIGR00436; HMM-score: 14.8)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA modification GTPase TrmE (TIGR00450; EC 3.6.-.-; HMM-score: 14.8)
    exopolysaccharide/PEP-CTERM locus tyrosine autokinase (TIGR03018; EC 2.7.10.2; HMM-score: 14.8)
    Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 13.2)
    Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 13.2)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTP-binding protein YsxC (TIGR03598; HMM-score: 13)
    Metabolism Energy metabolism Amino acids and amines ethanolamine utilization protein, EutP (TIGR02528; HMM-score: 12.4)
  • TheSEED  :
    • GTP-binding protein TypA/BipA
    Protein Metabolism Protein biosynthesis Universal GTPases  GTP-binding protein TypA/BipA
  • PFAM:
    P-loop_NTPase (CL0023) GTP_EFTU; Elongation factor Tu GTP binding domain (PF00009; HMM-score: 186.6)
    and 10 more
    MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 32.7)
    EFTPs (CL0575) GTP_EFTU_D2; Elongation factor Tu domain 2 (PF03144; HMM-score: 27.6)
    P-loop_NTPase (CL0023) Arf; ADP-ribosylation factor family (PF00025; HMM-score: 22.1)
    FeoB_N; Ferrous iron transport protein B (PF02421; HMM-score: 20.2)
    Septin; Septin (PF00735; HMM-score: 19.5)
    SRPRB; Signal recognition particle receptor beta subunit (PF09439; HMM-score: 16.6)
    cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 16)
    Dynamin_N; Dynamin family (PF00350; HMM-score: 15.6)
    Roc; Ras of Complex, Roc, domain of DAPkinase (PF08477; HMM-score: 14)
    Ras; Ras family (PF00071; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9744
    • Cytoplasmic Membrane Score: 0.0134
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0122
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004062
    • TAT(Tat/SPI): 0.000419
    • LIPO(Sec/SPII): 0.000523
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF55643 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAERAMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQLDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLLRFLWFGTS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPG_0622&oldid=73609"