From PneumoWiki
Jump to navigation Jump to search
TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_0689
  • pan locus tag?:
  • symbol: SPG_0689
  • pan gene symbol?: —
  • synonym:
  • product: PTS system, IIBCA components

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_0689
  • symbol: SPG_0689
  • product: PTS system, IIBCA components
  • replicon: chromosome
  • strand: +
  • coordinates: 671385..671897
  • length: 513
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001015 (671385..671897) NCBI
  • BioCyc:
  • MicrobesOnline: 5755958 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGATGAAAGATACATTCAAAAATGTCTTGTCTTTCGAATTTTGGCAAAAATTCGGTAAG
    GCTTTGATGGTAGTTATCGCGGTTATGCCGGCTGCTGGTTTGATGATTTCAATCGGTAAG
    TCTATCGTGATGATTAACCCAACCTTTACACCACTTGTCATCACAGGTGGAATTCTTGAG
    CAAATCGGTTGGGGGGTTATCGGTAACCTTCACATTTTGTTTGCCNTAGCCATTGGAGGA
    AGCTGGGCTAAAGAACGTGCTGGTGGTGCTTTCGCCGCTGGTCTTGCCTTTATCTTGATT
    AACCGTATCACTGGTACAATCTTTGGTGTGTCAGGCGATATGTTGAAAAATCCAGATGCT
    ATGGTAACTACTTTCTTTGGTGGTTCAATCAAAGTTGCTGATTACTTTATCAGTGTTCTT
    GAAGCTCCAGCCTTGAACATGGGGGGTATTCGTAGGGATTATCTCAGGTTTTGTAGGGGC
    AACTGCTTACAACAAATACTACAACTTCCGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    513

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_0689
  • symbol: SPG_0689
  • description: PTS system, IIBCA components
  • length: 170
  • theoretical pI: 10.0279
  • theoretical MW: 18221.6
  • GRAVY: 0.653254

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.69?  ExPASy
    Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208
  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 217.6)
    and 4 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 42.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 42.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 13.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 10.4)
  • TheSEED  :
    • PTS system, maltose and glucose-specific IIA component (EC 2.7.1.69)
    • PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)
    • PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69)
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIA component (EC 2.7.1.69)
    and 2 more
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69)
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 33.9)
    and 1 more
    no clan defined Chordopox_A15; Chordopoxvirus A15 protein (PF05846; HMM-score: 16.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.089389
    • TAT(Tat/SPI): 0.003013
    • LIPO(Sec/SPII): 0.016186
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF56757 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVMINPTFTPLVITGGILEQIGWGVIGNLHILFAXAIGGSWAKERAGGAFAAGLAFILINRITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGGIRRDYLRFCRGNCLQQILQLP

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA* regulon, MalR (repression) regulon
    CcpA*(TF)important in Global catabolite repression; RegPrecise 
    MalR(TF)important in Maltose utilization, Maltodextrin utilization; RegPrecise 

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPG_0689&oldid=73676"