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serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_0690 [new locus tag: SPG_RS03480 ]
  • pan locus tag?: PNEUPAN001720000
  • symbol: SPG_0690
  • pan gene symbol?: malT
  • synonym:
  • product: PTS system, IIBCA components

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_0690 [new locus tag: SPG_RS03480 ]
  • symbol: SPG_0690
  • product: PTS system, IIBCA components
  • replicon: chromosome
  • strand: +
  • coordinates: 672079..673566
  • length: 1488
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    TTGTATGGTACTTTGGAACGTTTGCTCTTGCCATTTGGTCTTCACCACATGTTGACTATC
    CCAATGAACTACACAGCTCTTGGTGGTACTTATGACATTTTAACTGGTGCAGCTAAAGGT
    ACTCAAGTATTCGGTCAAGACCCACTATGGCTTGCATGGGTAACAGACCTTGTAAACCTT
    AAAGGTACTGATGCTAGTCAATACCAACACTTGTTAGATACAGTACATCCAGCTCGTTTC
    AAAGTTGGACAAATGATCGGTTCATTCGGTATCTTGATGGGTGTGATTGTTGCTATCTAC
    CGTAATGTTGATGCTGACAAGAAACATAAATACAAAGGTATGATGATTGCAACAGCTCTT
    GCAACATTCTTGACAGGGGTTACTGAACCAATCGAATACATGTTCATGTTCATCGCAACA
    CCTATGTATCTTGTTTACTCACTTGTTCAAGGTGCTGCCTTCGCTATGGCTGACGTCGTA
    AACCTACGTATGCACTCATTCGGTTCAATCGAGTTCTTGACTCGTACACCTATTGCAATC
    AGTGCTGGTATTGGTATGGATATCGTTAACTTCGTTTGGGTAACTGTTCTCTTTGCTGTA
    ATCATGTACTTTATCGCNAACTTCATGATTCAAAAATTCAACTACGCAACTCCAGGGCGC
    AACGGAAACTACGAAACTGCTGAAGGTTCAGAAGAAACCAGCAGCGAAGTGAAAGTTGCA
    GCAGGCTCTCAAGCTGTAAACATTATCAACCTTCTTGGTGGACGTGTAAACATCGTTGAT
    GTTGATGCATGTATGACTCGTCTTCGTGTAACTGTTAAAGATGCAGATAAAGTAGGAAAT
    GCAGAGCAATGGAAAGCAGAAGGAGCTATGGGTCTTGTGATGAAAGGACAAGGGGTTCAA
    GCTATCTACGGTCCAAAAGCTGACATTTTGAAATCTGATATCCAAGATATCCTTGATTCA
    GGTGAAATCATTCCTGAAACTCTTCCAAGCCAAATGACTGAAGCACAACAAAACACTGTT
    CACTTCAAAGATCTTACTGAGGAAGTTTACTCAGTAGCAGACGGTCAAGTTGTTGCTTTG
    GAACAAGTAAAGGATCCAGTATTTGCTCAAAAAATGATGGGTGATGGATTTGCAGTAGAA
    CCTGCAAATGGAAACATTGTATCTCCAGTTTCAGGTACTGTATCAAGCATCTTCCCAACA
    AAACATGCTTTTGGTATTGTGACGGAAGCAGGTCTTGAAGTATTGGTTCACATTGGTTTG
    GACACAGTAAGTCTTGAAGGTAAACCATTTACAGTTCATGTTGCTGAAGGACAAAAAGTT
    GCAGCAGGAGATCTCCTTGTCACAGCTGACTTGGATGCTATCCGTGCAGCAGGACGTGAA
    ACTTCAACAGTAGTTGTCTTCACAAATGGTGATGCAATTAAATCAGTTAAATTAGAAAAA
    ACAGGTTCTCTTGCAGCTAAAACAGCAGTTGCTAAAGTAGAATTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1488

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_0690 [new locus tag: SPG_RS03480 ]
  • symbol: SPG_0690
  • description: PTS system, IIBCA components
  • length: 495
  • theoretical pI: 5.04301
  • theoretical MW: 53247.2
  • GRAVY: 0.258384

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.69?  ExPASy
    Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208
  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 548)
    and 15 more
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 202.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 190.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 173.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 150.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 146.3)
    Signal transduction Signal transduction PTS PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 146.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 120.9)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 60.3)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 60.3)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 41.7)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 41.7)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 35.6)
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 23)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion membrane fusion protein, HlyD family (TIGR01843; HMM-score: 14.9)
    Metabolism Transport and binding proteins Unknown substrate efflux transporter, RND family, MFP subunit (TIGR01730; HMM-score: 13.8)
  • TheSEED  :
    • PTS system, maltose and glucose-specific IIA component (EC 2.7.1.69)
    • PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)
    • PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69)
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIA component (EC 2.7.1.69)
    and 2 more
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)
    Carbohydrates Di- and oligosaccharides Maltose and Maltodextrin Utilization  PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69)
  • PFAM:
    Hybrid (CL0105) PTS_EIIA_1; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PF00358; HMM-score: 173.8)
    and 6 more
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 61.1)
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 51.6)
    Hybrid (CL0105) Biotin_lipoyl_2; Biotin-lipoyl like (PF13533; HMM-score: 17.3)
    Peptidase_M23; Peptidase family M23 (PF01551; HMM-score: 16.2)
    no clan defined DUF6256; Family of unknown function (DUF6256) (PF19770; HMM-score: 14)
    Hybrid (CL0105) RnfC_N; RnfC Barrel sandwich hybrid domain (PF13375; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.105446
    • TAT(Tat/SPI): 0.005166
    • LIPO(Sec/SPII): 0.00928
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF56694 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFGQDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNVDADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVNLRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPGRNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADKVGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEAQQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGTVSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADLDAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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