From PneumoWiki
Jump to navigation Jump to search
TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_1108
  • pan locus tag?:
  • symbol: SPG_1108
  • pan gene symbol?: —
  • synonym:
  • product: conserved hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_1108
  • symbol: SPG_1108
  • product: conserved hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1086180..1086302
  • length: 123
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001015 (1086180..1086302) NCBI
  • BioCyc:
  • MicrobesOnline: 5756377 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    ATGACTTGTGATTTTAAATTTGAAACTCTACAACTACATGCTGGTCAAGTTGTGGCTCCA
    GCTACTAAGTCTCGTGCAGTGCCGATTTATCAAACAACATTTTTTGTTTTTGATGACACG
    TAG
    60
    120
    123

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_1108
  • symbol: SPG_1108
  • description: conserved hypothetical protein
  • length: 40
  • theoretical pI: 5.56754
  • theoretical MW: 4525.14
  • GRAVY: 0.115

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase (TIGR01326; HMM-score: 39.4)
    Metabolism Amino acid biosynthesis Serine family O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase (TIGR01326; HMM-score: 39.4)
    and 1 more
    Metabolism Energy metabolism Amino acids and amines methionine gamma-lyase (TIGR01328; EC 4.4.1.11; HMM-score: 12.6)
  • TheSEED  :
    • O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
    • O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
    and 1 more
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
  • PFAM:
    PLP_aminotran (CL0061) Cys_Met_Meta_PP; Cys/Met metabolism PLP-dependent enzyme (PF01053; HMM-score: 19.6)
    no clan defined DCR; Dppa2/4 conserved region (PF14047; HMM-score: 17.6)
    and 1 more
    D-Glu_cyclase; D-glutamate cyclase (PF07286; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.1536
    • Cytoplasmic Membrane Score: 0.4495
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.3967
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.114687
    • TAT(Tat/SPI): 0.037555
    • LIPO(Sec/SPII): 0.039775
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF55732 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPG_1108&oldid=74095"