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TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_1638
  • pan locus tag?:
  • symbol: SPG_1638
  • pan gene symbol?: —
  • synonym:
  • product: serine/threonine protein kinase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_1638
  • symbol: SPG_1638
  • product: serine/threonine protein kinase
  • replicon: chromosome
  • strand: -
  • coordinates: 1584761..1585090
  • length: 330
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP001015 (1584761..1585090) NCBI
  • BioCyc:
  • MicrobesOnline: 5756905 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGA
    GGAGGTATGGCGGATGTNTACCTAGCCAAAGANTTAATNTTAGATGGGGAAGAAGTGGCA
    GTGAAGGTTTTGAGGACCAACTACCAGACGGACCCGATAGCTGTAGCTCGTTTTCAGCGT
    GAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
    GAGGAAGNCGGTCAACAGTATCTTGCAATGGAGTATGTTGCTTGGACTAGACCTCAAACG
    CTATATCAAGGAACATTATCCTCTTTCTAA
    60
    120
    180
    240
    300
    330

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_1638
  • symbol: SPG_1638
  • description: serine/threonine protein kinase
  • length: 109
  • theoretical pI: 8.8523
  • theoretical MW: 12030.8
  • GRAVY: -0.175472

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance TOMM system kinase/cyclase fusion protein (TIGR03903; HMM-score: 39.2)
  • TheSEED  :
    • Serine/threonine protein kinase PrkC, regulator of stationary phase
    A Gram-positive cluster that relates ribosomal protein L28P to a set of uncharacterized proteins  Serine/threonine protein kinase PrkC, regulator of stationary phase
    and 1 more
    Conserved gene cluster associated with Met-tRNA formyltransferase  Serine/threonine protein kinase PrkC, regulator of stationary phase
  • PFAM:
    PKinase (CL0016) Pkinase; Protein kinase domain (PF00069; HMM-score: 49.7)
    and 4 more
    PK_Tyr_Ser-Thr; Protein tyrosine and serine/threonine kinase (PF07714; HMM-score: 39.6)
    ABC1; ABC1 atypical kinase-like domain (PF03109; HMM-score: 15.5)
    no clan defined MRP-63; Mitochondrial ribosome protein 63 (PF14978; HMM-score: 13.7)
    Herpes_gp2; Equine herpesvirus glycoprotein gp2 (PF05955; HMM-score: 12.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001204
    • TAT(Tat/SPI): 0.000179
    • LIPO(Sec/SPII): 0.000274
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACF56840 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIQIGKIFAGRYRIVKQIGRGGMADVYLAKXLXLDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEXGQQYLAMEYVAWTRPQTLYQGTLSSF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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