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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_RS05315 [old locus tag: SPG_1054 ]
  • pan locus tag?: PNEUPAN002298000
  • symbol: zmpD
  • pan gene symbol?: zmpD
  • synonym:
  • product: zinc metalloprotease ZmpD

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_RS05315 [old locus tag: SPG_1054 ]
  • symbol: zmpD
  • product: zinc metalloprotease ZmpD
  • replicon: chromosome
  • strand: +
  • coordinates: 1024534..1029771
  • length: 5238
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_011072 (1024534..1029771) NCBI
  • BioCyc: SPG_RS05315 BioCyc
  • MicrobesOnline: see SPG_1054
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
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    1441
    1501
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    5221
    TTGTCATTATTAAAAAAAGATAAATTTTCCATTAGGAAAATAAAGGGTATTGTTGGTTCG
    ATATTCTTGGGGAGTTTTTTATTTGCACTGTCAGTTGTTGGTGTATCGACTTATCATTAC
    TTAGATTATAGTACTTTGACACAAACTGAACGTGATCAACTCAAACAAGGTAGACCTGAT
    GAATCAAAAGAGTCATATGCTTTGGTTTATGAAAAAGACGCATTACCAAACACAGGAAGT
    TCTCAATCTATTATGACTGTATTGGGTTTGTTAGCTATCGGGAGTCTTATTGTGATTATC
    ACAAAAGATAAAAAGAGGAAAAAAATAGCTACATTTTTGATTGTAGGGGCGACAGGTTTA
    GTTACACTATCAACTGCTTCAGCACTTAATTTGAATGCTAACATCCATGAGTCTGGACGT
    GATGGTGTGTTGCAAATTTCTGGTTACAGATATGTTGGTTACTTGGAGCTTGATGATAGA
    ACTGTTTCGTCGGTTTCTCCAGCATCAACTGTTTCTCCAGTTGAGCAACCCAAAGTTGTG
    ACCGACAAAGGCGAACCAGAAGTTCAGCCAGCGTTACCAGAAGCAGTTGTAACTGAAAAA
    GGGGAACCAGAAGTACAACCAGCCTTACCCGAAGCAGTTGTAACTGAAAAAGGGGAACCA
    GAAGTTCATGAGAAGCCTGACTATACGCAACCAATAGGTGCAAACCTTGTTGAGCCTGAA
    GTTCATGAGAAACTAGCATACACTGAACCTGTAGGTACAACAGGAGTAGATGAAAATGGA
    AACTTGATTGAGCCACCTGTTAACGATATTCCAGAGTATACTGAACCAATATCTACAGTT
    TCAGAAGTTGCATCAGAAAGAGAAGAGTTGCCTTCTTTACATACCGATATTCGTACAGAG
    ACTATTCCTAAAACCACTATAGAAGAATCTGATCCTAGCAAATTTATAGGCGATAATTCT
    GTTAAACAAGTTAGTGAGGATGGCGAACGTCAAATTGTTACTAGCTATGAAGAGTTACAT
    GGCAAAAAAATCAGCGAGTCAGTTGAAACAGTAACAATTTTGAAAGAAATGAAGCCTGAA
    ATTATTGTAAAAGGTACAAAAGAAAAAACGGCTCCTGTTTTAACCTTGACCAAAGTAACA
    GAAGATGCTATGAATCGTTCTGCCAACTTAAATTATGAGCTTGATAATAAAGATAATGCT
    GAAATATCAAGTATTGTAGCTGAAATTAAAGATGGTGATACAGTAGTTAAAAGGGTTGAT
    TTATCTAAAGAAAAATTAACTGACGCTGTACAAAATTTGGATTGGTTTAAAGATTATAAG
    ATTGCAACAACAATGATTTATGATCGTGGTCAAGGTTCTGAAACGTCTAAACTGGATGAA
    AGACCTCTGCGTTTGGAGTTGAAAAAGGTCGAAATTAAAAATATCGCATCTACTAATTTA
    GTGAAGGTAAATGATGATGGTACTGAAACACCTAGTGATTTTATGAATGAAAAACCTTCA
    GAAGAAGATGTTAAAAAAATGTACTTAAAAATCACTAGTCGCGATAATAAGGTAACTCGT
    TTAACTGTAGACTCTATTGAAGAAGTGACTGAAGAAGGTCAAAAACTTTACAAAATAACT
    GCTGAAGCACAAGATTTGATTCAACACACAGACCCAACGAAGGTTCGTAATAAGTATGTT
    TATTATATAGAANAACCCCATCCTAAAGAAGATNATGTCTACTATAACTTTAAAGATTTA
    GTAGATGCTATGAATACTGATAAAAATGGTACATTTAAACTTGGTGCAGATTTGAATGCC
    ACTGGTGTTCCAACACCTAAGAAATGGTATGTTGACGGCGACTTTAGAGGTACATTGAAG
    AGTGTAGAGGGGAAACATTATACTATCCACAACACGGAGCGTCCGTTATTCCAGAATATT
    ATTGGTGGTACAGTAACCAAAGTAAATCTGGGAAATGTAAATATCAATATGCCATGGGCA
    GACCGCATCGCACCGATTGCTGACACTATTAAAGGTGGCGCTAAAATTGAAGATGTCAAA
    GTGACTGGTAACGTATTAGGTAGAAACTGGGTATCTGGATTTATTGATAAGATTGACAAC
    CAAGGTACACTCAGAAATGTAGCCTTTATCGGAAATGTGACATCTGTAGGTGATGGTGGT
    CAATTCTTGACCGGTATCGTTGGTGAGAACTGGAAAGGACTAGTCGAACGTGCGTATGTT
    GACGCAAATCTTATTGGCAAGAAAGCCAAGGCTGCTGGTATTGCTTATTGGACACAAAAC
    AGTGGTGACAATCATAAAGTTGGTGTCGAAGGTGCAGTCAAGAAAGGAATTGTGAAGGGT
    ACCATTCAGGTAGAAAGTCCTGTTGAAGTCGGCGGTGCTGTTGGACGTTTGAGTCATCAT
    GGTTATATCGGGGAAGTCGTATCTATGATGAAAGTTAAGAAGGGTGAAATTTTTTATGGT
    TCTAGTGATATGAATGATGACCCATATTGGGTGGCGAATAATGTACGAGGAAATTATGTC
    GTTAATGGTGTGAGTGAAGGTACGATATCTTATGCTCGTGCTAAAGAACACCATCGTATC
    AAACCAATTTCACAGTCAGAAGCAGATACTAAAATTATGATGTTAGGTATTACAGCACAA
    GATTTTGCTATCAACGAACCTGTGGTCAATCGCTTAAACCGTTTAACCAGAAAAGAAGAT
    GAATATAAGTCAACCCAAGACTATAAAGTAGATCGAGATCTGGCTTATCGTAATATTGAG
    AAACTTCAACCATTTTATAACAAAGAATGGATTGTCAACCAAGGTAACAAACTTGCAGAA
    GATTCAAACTTAGCTAAGAAAGAAGTCCTTTCTGTTACGGGTATGAAGGATGGACAGTTT
    GTAACTGACTTATCAGATATTGATAAGATTATGGTTCACTATGCTGATGGTACTAAAGAA
    GAAATGGACGTCACTAAGAATGCTGATTCTAAAGTGAAACAAGTTCGTGAATATACCATC
    GCTGGACAAAACGTTGTTTATACACCAAATATGGTTGAGAAAGACCGTAACCAATTGATT
    CAAGATATCAAAGATAAGTTGGCGTCAGTTCAATTGATTTCTCCTGAAGTACGTGCTTTG
    ATGGATGCACGTAAGAAACCAGAAGAAAATACTGATGAACGTAAGAATGGTTATATTAAA
    GACCTTTACTTAGAAGAAAGCTTTGCTGAAACGAAAGCTAATCTTGATAAATTGGTTAAA
    TCCTTAGTTGAAAATGCAGATCATCAATTAAATAGTGACGAAACGGCTATGAAAGCACTT
    GTTAAGAAGGTGGATGAAAATAAAGCTAAAATCATGATGGCTCTGACTTATCTCAATCGT
    TACTATGATATCAAGTATGGGGATATGACTATCAAGAACTTGATGATGTTTAAACCTGAT
    TTCTATGGTAAATCAGTTGACCTTCTTGATTTCTTGATTCGAATTGGATCAAGTGAGAGA
    AATATCAAAGGTGACAGAACTTTGGATGCTTATCGTGATATGATTGGTGGAACTATTGGT
    AAGTCTGAATTACATGGATTCTTAGATTACAATATGCGTCTCTTCACTAACGATACTGAT
    TTAAATGATTGGTTCATCCATGCAGCTAAGAATGTATATGTATCAGAACCTCAAACAACG
    AACCCAGATTTTGTTAATAAACGACATCGTGCATTTGATGGTTTGAACAACGGTGTTCAT
    AATCGTATGATTCTACCTCTATTAACTCTTAAGAATGCACATATGTTCTTGATTTCAACT
    TACAATACAATGGCTTATAGTTCTTTTGAGAAATATGGTAAGTATACAGAAGAAGCTAGA
    AATGAATTCAAAAAAGAAATTGATAAGGTTGCACATGCTCAACAAACATACTTAGACTTC
    TGGTCACGTTTAGCATTGCCAAGCGTACGTGACCAATTACTCAAGAGTGAGAATAGGGTA
    CCAACTCCTGTGTGGGATAACCAAAACTATAGTGGTATTAAAGGAATAAACCGTATGGGT
    TATGATGAGAAGAAAGTACCAATTGCGCCAATTCGTGAGTTATATGGTCCAACTTGGAAA
    TTCCATAATACCAACTGGAATATGGGAGCTATGGCATCTATTTTCCCAAATCCTAATAAC
    AATGACCAAGTTTATTTCATGGGAACAAATATGATTAGTCCGTTTGGTATTTCAGCCTTT
    ACTCATGAAACTACACACGTTAATGATAGAATGCTTTACTTCGGTGGTCATAGACACCGT
    CAAGGTACAGACGTCGAAGCCTATGCTCAAGGTATGCTACAAACTCCGTCAAGTATTGGT
    CACCAAGGTGAATATGGTGCTTTAGGTTTGAACATGGCTTATCATCGTGAAAATGATGGT
    GACCAATGGTATAACTATGACCCTGATAAGCTTCAAACTCGTGAAGATATCGATCGATAT
    ATGAAAAACTATAATGAAGCACTGATGATGCTAGATCATGTAGAAGCAGACGCCGTACTT
    CCACAATTGAATGGTGATAATAGCAAGTGGTTCAAGAAAATTGATAGAGAAATGCGCAGA
    AATCTTGGGGATGGTTTGAATAACTTAGTAGCACCGCACCAATGGGACAACGTTCGTGAC
    TTAAATCAAGAAGAGAGTTCTAAGAAATTATCAAGTATTAACGATTTGATTGATAATAAT
    TTCATGACCAAACACGGAAATCCAGGTAACGGACGTTATAGACCAGAGGATTTTAGACCA
    AACTCAGCTTACGTAAATGTCAATATGATGGCAGGAATTTACGGTGGGAATACGAGTCAA
    GGTGCTCCTGGTTCATTATCGTTCAAACATAATGCCTTCCGTATGTGGGGTTATTATGGA
    TATGACAAAGGTTTCACTAGTTATGTATCTAGCAAATATCAAGGTGAAGCTGATAAACAA
    AACCAGGGTAGATTAGGTGATGATTTCATTATCAAAAAAGTTTCAAACAACCAATTCTCA
    AATCTTGAAGATTGGAAGAAATATTGGTATCATGATGTGAAATCCAGAGCTGAAAAAGGA
    TTCACAGAGATTACAATTGATGGACAAACCATTCACAACTATAATGAACTGAAAGACTTA
    TTCGACAAAGCTGTCACAGAAGACCTCAAGAAAGCTGGAAACTACTCAAATACTGAGAAT
    TTGAAATCCAAAGTCTTCAAAGCTCTTCTTAAAAACACAGACGGTTTCTTTAATCCATTG
    TTCAAAAAAGACATTTAA
    60
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    5220
    5238

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_RS05315 [old locus tag: SPG_1054 ]
  • symbol: ZmpD
  • description: zinc metalloprotease ZmpD
  • length: 1745
  • theoretical pI: 5.99551
  • theoretical MW: 196525
  • GRAVY: -0.613196

⊟Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 22)
  • TheSEED: see SPG_1054
  • PFAM:
    no clan defined Peptidase_M26_C; M26 IgA1-specific Metallo-endopeptidase C-terminal region (PF07580; HMM-score: 836.1)
    and 7 more
    Peptidase_M26_N; M26 IgA1-specific Metallo-endopeptidase N-terminal region (PF05342; HMM-score: 259.7)
    G5 (CL0593) G5; G5 domain (PF07501; HMM-score: 34.6)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 21.6)
    DUF1474; Protein of unknown function (DUF1474) (PF07342; HMM-score: 17)
    B_GA (CL0598) B; B domain (PF02216; HMM-score: 14)
    no clan defined Pectate_lyase_5; Putative pectate lyase-like adhesive domain (PF20585; HMM-score: 12.6)
    Remorin_C; Remorin, C-terminal region (PF03763; HMM-score: 9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 10
    • Extracellular Score: 0
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0004
    • Cytoplasmic Membrane Score: 0.0221
    • Cell wall & surface Score: 0.8592
    • Extracellular Score: 0.1183
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.129212
    • TAT(Tat/SPI): 0.002034
    • LIPO(Sec/SPII): 0.036682
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000054777 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYSTLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITKDKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDRTVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVSEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDWFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEXPHPKEDXVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADHQLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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