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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-NOV-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_RS07125 [old locus tag: SPG_1428 ]
  • pan locus tag?: PNEUPAN002830000
  • symbol: SPG_RS07125
  • pan gene symbol?: pgl
  • synonym:
  • product: lactonase family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_RS07125 [old locus tag: SPG_1428 ]
  • symbol: SPG_RS07125
  • product: lactonase family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1380713..1381726
  • length: 1014
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_011072 (1380713..1381726) NCBI
  • BioCyc: SPG_RS07125 BioCyc
  • MicrobesOnline: see SPG_1428
  • PneumoBrowse for strain D39V: SPV_1333 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAAGAAACTGTTTATTTTGGAACTTATACACGTCGTACTTCTCAAGGGATTTACAAG
    GCAGACTTTGATACAGAAACTGGTCAGCTTTCAAATCTAGAACTTTTTGCAGCTGAGCCA
    AGTCCAACCTACCTTGCCTTTGACCAGCACCAACATTTATACACTGTTGGTAGCCAAGAC
    GATNAGGGGGGAATTGCAGCCTATCAAACTGACGGGACTGTGTTAAATCATGTTGTTGAA
    GAAGGAGCTCCCCACTGTTATGTTGCTGTCGATGAAAAGCGTGATTTGGTTTACGCAGCC
    AACTATCACAAGGGACAAGTCCTTGTTTATAAACGCCAGGAAGATGGTAGTCTTCTACTT
    AGTGATATGGATCAACACAGTGGCCAAGGTCCACATGAAAATCAAGCTTCCCCCCATGTT
    CACTATACAGATTTAACACCTGACCACTATCTAGTGACCTGCGACTTGGGAACTGACCAA
    GTCATCACCTATGACCTCGATCAAGAAGGAAAATTATCTAAGCTCTATACCTATCACAGC
    AAGCCAGGAGCAGGCTCACGCCATATCATTTTCCATAACCACTATAAAATCGCTTATCTC
    ATTTGTGAACTCAATAGTACTATCGAAGTTTTAATCTACGATGGCGTTGGCGAATTTGTA
    CGTATGCAGGTTATTTCAACTTTACCAGAAGCTTACGAAGGCTTTAATGGAACCGCTGCT
    ATTCATCTCTCTAAAGACGGTAAATACCTCTACGCTTCTAACCGTGGCCATGATTCTATC
    GCAGTATATACCATCCTTGCGGACGGTAGCTTAGAGTTATTAGAAATCGTTCCAACGCAT
    GGTCAGACTCCACGTGATTTTGATTTGACACCCGACCAAAAATTTCTCATTGTTGTCCAT
    CAAGACTCTGACAATGCAACTGTCTTTAAACGTAATTGTGACAATGGTCGTCTAGCAGAA
    CTCTCCAACGAATTCCATGTTCCCGAAGCAGTCTGCATCCGTTTTGCTCCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1014

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_RS07125 [old locus tag: SPG_1428 ]
  • symbol: SPG_RS07125
  • description: lactonase family protein
  • length: 337
  • theoretical pI: 4.96897
  • theoretical MW: 37612.5
  • GRAVY: -0.400595

⊟Function[edit | edit source]

  • TIGRFAM:
    PQQ-dependent catabolism-associated beta-propeller protein (TIGR03866; HMM-score: 18.1)
  • TheSEED: see SPG_1428
  • PFAM:
    Beta_propeller (CL0186) Lactonase; Lactonase, 7-bladed beta-propeller (PF10282; HMM-score: 390.5)
    and 2 more
    SGL; SMP-30/Gluconolactonase/LRE-like region (PF08450; HMM-score: 26.1)
    DUF1513; Protein of unknown function (DUF1513) (PF07433; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01014
    • TAT(Tat/SPI): 0.00058
    • LIPO(Sec/SPII): 0.001183
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000665630 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTYLAFDQHQHLYTVGSQDDXGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANYHKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQVITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGEFVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEIVPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIRFAP

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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