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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-NOV-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_RS07400 [old locus tag: SPG_1486 ]
  • pan locus tag?: PNEUPAN002894000
  • symbol: glmM
  • pan gene symbol?: glmM
  • synonym:
  • product: phosphoglucosamine mutase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPG_RS07400 [old locus tag: SPG_1486 ]
  • symbol: glmM
  • product: phosphoglucosamine mutase
  • replicon: chromosome
  • strand: -
  • coordinates: 1433650..1435002
  • length: 1353
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_011072 (1433650..1435002) NCBI
  • BioCyc: SPG_RS07400 BioCyc
  • MicrobesOnline: see SPG_1486
  • PneumoBrowse for strain D39V: SPV_1390 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGGTAAATATTTTGGGACTGATGGAGTCCGTGGAGAAGCTAACCTAGAGCTAACACCA
    GAATTAGCCTTTAAACTAGGACGTTTTGGAGGCTATGTTCTTAGTCAACATGAAACGGAA
    GCGCCGAAAGTCTTTGTAGGACGTGACACACGTATTTCAGGGGAAATGCTGGAATCGGCC
    TTGGTGGCAGGTCTCCTTTCAGTAGGGATTCACGTATACAAACTTGGTGTCCTTGCAACA
    CCAGCAGTAGCTTACTTGGTTGAAACTGAAGGAGCAAGTGCCGGTGTCATGATTTNTGCT
    AGCCACAACCCAGCCCTTGATAACGGAATCAAGTTCTTTGGCGGTGATGGCTTCAAACTA
    GATGATGAAAAAGAAGCAGAAATTGAAGCCTTGCTAGATGCTGAGGAAGACACTCTTCCT
    NGTCCAAGTGCAGAAGGCTTAGGAATTTTGGTAGATTATCCAGAAGGCTTGCGTAAGTAT
    GAAGGATACCTTGTTTCAACTGGAACTCCTCTTGATGGAATGAAGGTTGCCTTGGATACA
    GCTAATGGAGCAGCTTCTACCAGTGCCCGTCAAATCTTTGCAGACCTTGGTGCCCAATTG
    ACGGTTATCGGGGAAACACCAGACGGTCTTAACATCAACCTTAATGTTGGTTCAACACAT
    CCAGAAGCCCTTCAAGAAGTGGTCAAAGAAAGTGGGTCAGCTATTGGTTTGGCCTTTGAT
    GGAGACAGTGACCGCTTGATTGCTGTTGATGAGAATGGTGACATCGTCGATGGTGACAAG
    ATTATGTACATCATCGGAAAATACCTTTCTGAAAAAGGACAATTGGCTCAAAATACAATT
    GTGACAACTGTTATGTCTAACCTTGGTTTCCACAAGGCCTTGAATCGCGAAGGTATTAAC
    AAGGCAGTTACTGCAGTTGGTGACCGCTACGTTGTTGAAGAAATGAGAAAATCAGGTTAC
    AACCTTGGTGGTGAACAGTCTGGTCACGTTATCTTGATGGATTACAATACCACAGGTGAT
    GGTCAATTATCAGCAGTTCAATTGACTAAAATCATGAAGGAAACTGGTAAGAGCTTATCA
    GAGTTGGCGGCAGAAGTAACGATTTATCCACAAAAATTAGTTAATATCCGAGTGGAAAAC
    GTCATGAAGGAAAAGGCCATGGAAGTGCCAGCTATCAAGGCCATCATCGAGAAGATGGAA
    GAAGAAATGGCGGGGAACGGCCGTATCCTTGTTCGTCCAAGTGGAACAGAACCCCTCTTG
    CGTGTTATGGCAGAAGCGCCTACAACAGAAGAAGTAGACTACTATGTTGATACCATCACA
    GATGTAGTTCGTGCTGAAATTGGGATTGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1353

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPG_RS07400 [old locus tag: SPG_1486 ]
  • symbol: GlmM
  • description: phosphoglucosamine mutase
  • length: 450
  • theoretical pI: 4.28506
  • theoretical MW: 47879.9
  • GRAVY: -0.0783482

⊟Function[edit | edit source]

  • reaction:
    EC 5.4.2.10?  ExPASy
    Phosphoglucosamine mutase Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate
  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan phosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 660.7)
    Metabolism Central intermediary metabolism Amino sugars phosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 660.7)
    and 2 more
    Metabolism Central intermediary metabolism Amino sugars phosphoglucosamine mutase (TIGR03990; EC 5.4.2.10; HMM-score: 333.6)
    Metabolism Energy metabolism Sugars phosphoglucomutase, alpha-D-glucose phosphate-specific (TIGR01132; EC 5.4.2.2; HMM-score: 28.6)
  • TheSEED: see SPG_1486
  • PFAM:
    no clan defined PGM_PMM_I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I (PF02878; HMM-score: 142.4)
    PGM_PMM_III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III (PF02880; HMM-score: 114.2)
    and 3 more
    PGM_PMM_IV; Phosphoglucomutase/phosphomannomutase, C-terminal domain (PF00408; HMM-score: 61.5)
    PGM_PMM_II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II (PF02879; HMM-score: 54.2)
    DUF3659; Protein of unknown function (DUF3659) (PF12396; HMM-score: 16.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010198
    • TAT(Tat/SPI): 0.001184
    • LIPO(Sec/SPII): 0.000745
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMIXASHNPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPXPSAEGLGILVDYPEGLRKYEGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGSTHPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMDYNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAIKAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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