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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-NOV-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae G54
  • locus tag: SPG_RS09525 [old locus tag: SPG_1904 ]
  • pan locus tag?: PNEUPAN003541000
  • symbol: SPG_RS09525
  • pan gene symbol?:
  • synonym:
  • product: ABC transporter permease

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPG_RS09525 [old locus tag: SPG_1904 ]
  • symbol: SPG_RS09525
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 1815577..1816314
  • length: 738
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_011072 (1815577..1816314) NCBI
  • BioCyc: SPG_RS09525 BioCyc
  • MicrobesOnline: see SPG_1904
  • PneumoBrowse for strain D39V: SPV_1800 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGAAACGATGGATAGCACTTAGTAAGATAGAATTTTTATTGACCAAACGACAATTAATC
    TATTATCTATTGTCGGTAGGGATGCCGACGGCTTTCTATTTATTTTTTTCTGGTATCTAT
    CAGGACACACCAGGTGAACTCGCGAATTTTATGCGTGATTACCTCATCTCCATGACTGCC
    TTTTCCATGATGTCGACAACTATCCTCTCATTTCCAGCTGTTTTACATACCGATAAGATG
    AACAACTGGCAGAAAACATTGCGTCATAGCCCTGTAAATATGGTAGAATATTATCTATCA
    AAGATAACAAGTATGCTGGTTGATTATTTGGTCTCAATTCTGGTTGTTTTTACAGTTGGA
    CATTTTGTAAGAGGTGTAGACATGCCTCTAGTAAAATGGGTTGGAGCTGCGATTTTGCTG
    ATTGTGGGGAGTATTGCTTTTGTAGCACTTGGCTTGACCTTGACTCTCTTACCAACTAGT
    CAGCTGATGTCTGTTGTGGGCAATCTTCTTTATCTAGGATTGGCTGTTTTAGGCGGACTC
    TGGATGCCCATTTCTTTATTTCCAGACTGGATGCAAGCAGTTGGTAAGTGTCTCCCGACC
    TATCAATTGATGGAGTTGCTCAAGACCTTCTTAAACGAGGGTGGCATCAATCTATCAGCC
    ACAGTTTATCTACTTGTTTTTTCAGCAGTTTTGTTTGGTTTGACCATTTACCTTCAAGGT
    CATAAGGAGAATGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    738

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPG_RS09525 [old locus tag: SPG_1904 ]
  • symbol: SPG_RS09525
  • description: ABC transporter permease
  • length: 245
  • theoretical pI: 9.14464
  • theoretical MW: 27462.7
  • GRAVY: 0.721224

Function[edit | edit source]

  • TIGRFAM:
    ABC transporter efflux protein, DrrB family (TIGR00025; HMM-score: 28.5)
    and 3 more
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter membrane protein (TIGR01247; HMM-score: 21.5)
    lantibiotic protection ABC transporter permease subunit, MutE/EpiE family (TIGR03732; HMM-score: 13.5)
    Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 9.7)
  • TheSEED: see SPG_1904
  • PFAM:
    ABC-2 (CL0181) ABC2_membrane; ABC-2 type transporter (PF01061; HMM-score: 58.4)
    ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 51.4)
    and 7 more
    ABC2_membrane_4; ABC-2 family transporter protein (PF12730; HMM-score: 25.7)
    ABC2_membrane_5; ABC-2 family transporter protein (PF13346; HMM-score: 14.2)
    CPA_AT (CL0064) Mem_trans; Membrane transport protein (PF03547; HMM-score: 12.9)
    ABC-2 (CL0181) ABC2_membrane_2; ABC-2 family transporter protein (PF12679; HMM-score: 12.1)
    no clan defined DUF6704; Family of unknown function (DUF6704) (PF20447; HMM-score: 10.5)
    PrgI; PrgI family protein (PF12666; HMM-score: 8.5)
    YrvL; Regulatory protein YrvL (PF14184; HMM-score: 7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009196
    • TAT(Tat/SPI): 0.000355
    • LIPO(Sec/SPII): 0.0044
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000832837 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTPGELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKITSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTSQLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINLSATVYLLVFSAVLFGLTIYLQGHKENA

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]