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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_0922 [new locus tag: SPH_RS04460 ]
  • pan locus tag?: PNEUPAN001791000
  • symbol: SPH_0922
  • pan gene symbol?: glnP4
  • synonym:
  • product: amino acid ABC transporter, permease protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0922 [new locus tag: SPH_RS04460 ]
  • symbol: SPH_0922
  • product: amino acid ABC transporter, permease protein
  • replicon: chromosome
  • strand: +
  • coordinates: 853172..853855
  • length: 684
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAATTTTTCTTTTTTACCTAAGTATTTACCTTATTTTAACTATGGGGCTGTTGTGACG
    ATTCTTATTTCTATCTGTGTTATCTTTTTGGGAACTATTTTGGGTGTTGTCTTGGCTTTT
    GGGCAACGTTCAAAGTTTAAACCGCTTGTTTGGTTGGCCAACTTGTACGTTTGGATTTTC
    CGTGGGACACCGATGATGGTTCAAATTATGATTGCCTTTGCTCTTATGCATATCAATGCT
    CCGACTATTCAGATTGGAATTTTAGGTGTTGATTTTTCGCGTCTGATTCCAGGGATTTTG
    ATTATCTCTATGAATAGTGGTGCTTATGTTTCGGAGACTGTTCGTGCCGGAATCAATGCG
    GTTCCAAAAGGTCAGCTAGAGGCGGCTTATTCGCTAGGGATTCGTCCTAAAAATGCGATG
    CGTTATGTGATTTTGCCACAAGCAGTCAAAAATATCTTGCCAGCATTGGGGAACGAATTT
    ATCACCATTATCAAGGACAGCTCCCTCTTATCAGCTATTGGGGTCATGGAGTTGTGGAAT
    GGGGCTACAACAGTTTCTACAACAACCTATCTACCTTTAACACCACTTTTATTTGCAGCA
    TTTTACTACTTGATTATGACCTCTATTCTGACAGTAGCCTTGAAAGCTTTTGAAAAACAT
    ATGGGACAAGGAGATAAGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    684

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPH_0922 [new locus tag: SPH_RS04460 ]
  • symbol: SPH_0922
  • description: amino acid ABC transporter, permease protein
  • length: 227
  • theoretical pI: 10.1212
  • theoretical MW: 24958.8
  • GRAVY: 0.73348

Function[edit | edit source]

  • TIGRFAM:
    ectoine/hydroxyectoine ABC transporter, permease protein EhuC (TIGR03004; HMM-score: 135)
    ectoine/hydroxyectoine ABC transporter, permease protein EhuD (TIGR03003; HMM-score: 129.6)
    and 7 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family (TIGR01726; HMM-score: 66.9)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 27.5)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 22.5)
    2-aminoethylphosphonate ABC transport system, membrane component PhnV (TIGR03255; HMM-score: 16.2)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 15.4)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 12.5)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 11)
  • TheSEED  :
    • Arginine ABC transporter, substrate-binding and permease protein
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 73.8)
    and 1 more
    no clan defined Phlebovirus_G1; Phlebovirus glycoprotein G1 (PF07243; HMM-score: 8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 3
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002209
    • TAT(Tat/SPI): 0.000314
    • LIPO(Sec/SPII): 0.010569
  • predicted transmembrane helices (TMHMM): 3

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRSKFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILIISMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEFITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFEKHMGQGDKK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulators: ArgR2* (activation (repression)) regulon, AhrC* (activation (repression)) regulon, ArgR1* (activation (repression)) regulon
    ArgR2*(TF)important in Arginine biosynthesis, Arginine degradation; RegPrecise 
    AhrC*(TF)important in Arginine biosynthesis, Arginine degradation; RegPrecise 
    ArgR1*(TF)important in Arginine biosynthesis, Arginine degradation; RegPrecise 

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]