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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Hungary19A-6
- locus tag: SPH_1015 [new locus tag: SPH_RS04915 ]
- pan locus tag?: PNEUPAN001886000
- symbol: SPH_1015
- pan gene symbol?: —
- synonym:
- product: zinc-dependent metalloprotease
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPH_1015 [new locus tag: SPH_RS04915 ]
- symbol: SPH_1015
- product: zinc-dependent metalloprotease
- replicon: chromosome
- strand: +
- coordinates: 939891..940340
- length: 450
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000936 (939891..940340) NCBI
- BioCyc: see SPH_RS04915
- MicrobesOnline: 5695852 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_2244 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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421ATGAAACTGACTGATTATGTCAAGCAGGTTTCACTAGAAGACTTCGGGAGAGCTTTTATC
CATCATGTCCAGTGGAATAGGCGTCTACGTTCGACAGGTGGGCGATTTTTCCCCAAAGAT
GGGCATCTGGATTTTAATCCCAAGGTTTATCAGAAACTGGGTATGGAGGTTTTTAGGAAA
ATTGTCCGACATGAACTCTGTCATTATCACCTTTATTTCCAAGGGAAGGGCTATCAACAC
AAGGATCGGGATTTTAAGGAACTTTTGAAAGCAGTGGATGGATTACGGTTTGTACCATCC
TTGCCCAATAGTAACTCTAAACCACTCAAGCTTTATCGTTGTCAATCCTGCCAGCAAAGG
TATCAGCGCAAGCGTAGGATTGATACCAAACGCTATCGCTGTGGACTTTGTCGAGGTAAA
TTGCTTCTGATAAATCAGCCTGAGGACTGA60
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450
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPH_1015 [new locus tag: SPH_RS04915 ]
- symbol: SPH_1015
- description: zinc-dependent metalloprotease
- length: 149
- theoretical pI: 10.5965
- theoretical MW: 17973.7
- GRAVY: -0.868456
⊟Function[edit | edit source]
- TIGRFAM: Protein fate Protein modification and repair hydrogenase nickel insertion protein HypA (TIGR00100; HMM-score: 11.4)
- TheSEED :
- Putative metallopeptidase (Zinc) SprT family
- PFAM: Peptidase_MA (CL0126) SprT-like; SprT-like family (PF10263; HMM-score: 36.2)Zn_Beta_Ribbon (CL0167) Zn_ribbon_SprT; SprT-like zinc ribbon domain (PF17283; HMM-score: 34.5)and 4 moreno clan defined FlhC; Flagellar transcriptional activator (FlhC) (PF05280; HMM-score: 22.2)HypA; Hydrogenase/urease nickel incorporation, metallochaperone, hypA (PF01155; HMM-score: 12.5)Zn_Beta_Ribbon (CL0167) Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 10.4)C1 (CL0006) C1_4; TFIIH C1-like domain (PF07975; HMM-score: 9.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.993
- Cytoplasmic Membrane Score: 0.0019
- Cell wall & surface Score: 0.0022
- Extracellular Score: 0.0029
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005951
- TAT(Tat/SPI): 0.000543
- LIPO(Sec/SPII): 0.000769
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLDFNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLPNSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_2244 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]