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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1163 [new locus tag: SPH_RS05645 ]
  • pan locus tag?: PNEUPAN002213000
  • symbol: SPH_1163
  • pan gene symbol?: lafB
  • synonym: cpoA
  • product: glycosyl transferase CpoA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1163 [new locus tag: SPH_RS05645 ]
  • symbol: SPH_1163
  • product: glycosyl transferase CpoA
  • replicon: chromosome
  • strand: +
  • coordinates: 1070368..1071411
  • length: 1044
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGAGAAAAAGAAATTACGCATCAATATGTTGAGTTCAAGTGAGAAAGTAGCAGGACAA
    GGAGTTTCAGGTGCTTACCGTGAATTAGTTCGTCTTCTTCACCGTGCTGCCAAGGACCAA
    TTGATTGTTACAGAAAATCTTCCAATCGAGGCAGATGTGACTCACTTTCATACCATTGAT
    TTTCCCTATTATTTATCAACCTTCCAAAAGAAACGCTCAGGGAGAAAGATTGGCTATGTG
    CATTTCTTGCCAGCTACACTTGAGGGAAGTTTGAAAATTCCATTTTTCTTAAAGGGAATT
    GTGAAACGCTATGTATTTTCTTTTTACAACCGGATGGAGCACTTGGTTGTGGTCAATCCT
    ATGTTTATTGAGGATTTGGTAGCAGCTGGTATTTCACGTGAAAAAGTGAGCTATATTCCT
    AACTTTGTCAACAAGGAAAAATGGCATCCTCTACCACAAGAAGAGGTAGTCAGACTGCGC
    ACAAATCTTGGTCTTAGTGACAATCAGTTTATCGTAGTAGGTGCTGGGCAAGTTCAGAAA
    CGTAAAGGGATTGATGACTTTATCCGTCTGGCTGAGGAATTGCCTCAGATTACCTTTATC
    TGGGCTGGTGGCTTCTCTTTTGGTGGTATGACAGATGGTTATGAACACTATAAGAAAATT
    ATGGAAAATCCCCCTAAAAATTTGATTTTTCCAGGCATTGTATCGCCAGAGCGGATGCGC
    GAATTGTATGCTCTAGCGGATCTTTTCTTGTTGCCTAGTTACAATGAGCTCTTTCCTATG
    ACTATTTTAGAAGCTGCGAGTTGTGAGGCTCCTATTATGTTGCGTGATTTAGATCTCTAT
    AAGGTGATTTTGGAGGGAAATTATCGGGCGACAGCGGGTAGAGAAGAGATGAAAGAGGCT
    ATTTTGGAATATCAAGCAAATCCTGTTGCCTTAAAAGATCTCAAAGAAAAGGCTAAGAAT
    ATTTCCAGAGAGTATTCTGAAGAGCATCTGTTACAAATCTGGTTGGACTTTTATGAGAAA
    CAAGCCGCTTTAGGGAGAAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1044

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1163 [new locus tag: SPH_RS05645 ]
  • symbol: SPH_1163
  • description: glycosyl transferase CpoA
  • length: 347
  • theoretical pI: 8.98763
  • theoretical MW: 39942.1
  • GRAVY: -0.217867

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function Enzymes of unknown specificity glycosyltransferase, MSMEG_0565 family (TIGR04047; HMM-score: 59.6)
    and 8 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA (TIGR03999; EC 2.4.1.-; HMM-score: 44.9)
    glycosyltransferase, GG-Bacteroidales peptide system (TIGR04157; EC 2.4.1.-; HMM-score: 40.7)
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03088; HMM-score: 37.4)
    D-inositol-3-phosphate glycosyltransferase (TIGR03449; EC 2.4.1.250; HMM-score: 35.3)
    PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family (TIGR04063; EC 2.4.-.-; HMM-score: 33.2)
    colanic acid biosynthesis glycosyltransferase WcaI (TIGR04007; EC 2.4.-.-; HMM-score: 32.5)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen synthase, Corynebacterium family (TIGR02149; HMM-score: 29.1)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen/starch synthase, ADP-glucose type (TIGR02095; EC 2.4.1.21; HMM-score: 12.6)
  • TheSEED  :
    • Glycosyltransferase LafB, responsible for the formation of Gal-Glc-DAG
    Cell Wall and Capsule Gram-Positive cell wall components Polyglycerolphosphate lipoteichoic acid biosynthesis  Glycosyltransferase LafB, responsible for the formation of Gal-Glc-DAG
  • PFAM:
    GT-B (CL0113) Glycos_transf_1; Glycosyl transferases group 1 (PF00534; HMM-score: 51.9)
    Glyco_trans_1_4; Glycosyl transferases group 1 (PF13692; HMM-score: 44.2)
    and 3 more
    Glyco_transf_4; Glycosyltransferase Family 4 (PF13439; HMM-score: 27.3)
    Glyco_trans_1_2; Glycosyl transferases group 1 (PF13524; HMM-score: 17.7)
    Glyco_trans_4_4; Glycosyl transferase 4-like domain (PF13579; HMM-score: 11.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0831
    • Cytoplasmic Membrane Score: 0.8735
    • Cell wall & surface Score: 0.0006
    • Extracellular Score: 0.0428
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005135
    • TAT(Tat/SPI): 0.000715
    • LIPO(Sec/SPII): 0.000861
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVTENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVKRYVFSFYNRMEHLVVVNPMFIEDLVAAGISREKVSYIPNFVNKEKWHPLPQEEVVRLRTNLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYKKIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRDLDLYKVILEGNYRATAGREEMKEAILEYQANPVALKDLKEKAKNISREYSEEHLLQIWLDFYEKQAALGRK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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