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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1205 [new locus tag: SPH_RS05845 ]
  • pan locus tag?: PNEUPAN002251000
  • symbol: SPH_1205
  • pan gene symbol?: hlpA
  • synonym:
  • product: DNA-binding protein HU 1 (DNA-binding protein II) (HB)

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1205 [new locus tag: SPH_RS05845 ]
  • symbol: SPH_1205
  • product: DNA-binding protein HU 1 (DNA-binding protein II) (HB)
  • replicon: chromosome
  • strand: +
  • coordinates: 1101950..1102225
  • length: 276
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    ATGGCAAACAAACAAGATTTGATCGCTAAAGTAGCAGAAGCTACAGAATTGACTAAGAAA
    GACTCAGCAGCAGCAGTTGAAGCTGTATTTGTAGCAGTAGCTGACTATCTTGCAGCTGGT
    GAAAAAGTTCAGTTGATCGGTTTTGGTAACTTTGAAGTTCGTGAGCGTGCAGAACGTAAA
    GGTCGCAACCCACAAACTGGTAAAGAAATGACAATTGCAGCTTCTAAAGTACCAGCATTC
    AAAGCTGGTAAAGCTCTTAAAGACGCTGTTAAATAA
    60
    120
    180
    240
    276

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1205 [new locus tag: SPH_RS05845 ]
  • symbol: SPH_1205
  • description: DNA-binding protein HU 1 (DNA-binding protein II) (HB)
  • length: 91
  • theoretical pI: 10.2074
  • theoretical MW: 9678.12
  • GRAVY: -0.215385

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integration host factor, beta subunit (TIGR00988; HMM-score: 76.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integration host factor, alpha subunit (TIGR00987; HMM-score: 74.8)
    and 1 more
    Genetic information processing DNA metabolism Chromosome-associated proteins putative DNA-binding protein (TIGR01201; HMM-score: 22.8)
  • TheSEED  :
    • DNA-binding protein HBsu
    DNA Metabolism DNA Metabolism - no subcategory DNA structural proteins, bacterial  DNA-binding protein HBsu
  • PFAM:
    IHF-likeDNA-bdg (CL0548) Bac_DNA_binding; Bacterial DNA-binding protein (PF00216; HMM-score: 114.9)
    and 4 more
    HU-HIG; HU domain fused to wHTH, Ig, or Glycine-rich motif (PF18291; HMM-score: 34)
    no clan defined DUF2267; Uncharacterized conserved protein (DUF2267) (PF10025; HMM-score: 15.4)
    IHF-likeDNA-bdg (CL0548) HU-CCDC81_euk_2; CCDC81 eukaryotic HU domain 2 (PF18289; HMM-score: 13.5)
    HU-DNA_bdg; DNA-binding domain (PF14848; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.949
    • Cytoplasmic Membrane Score: 0.0005
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0504
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003628
    • TAT(Tat/SPI): 0.000952
    • LIPO(Sec/SPII): 0.000577
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MANKQDLIAKVAEATELTKKDSAAAVEAVFVAVADYLAAGEKVQLIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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