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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1293 [new locus tag: SPH_RS06260 ]
  • pan locus tag?: PNEUPAN002414000
  • symbol: SPH_1293
  • pan gene symbol?: dhaS
  • synonym:
  • product: probable dihydroxyacetone kinase regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1293 [new locus tag: SPH_RS06260 ]
  • symbol: SPH_1293
  • product: probable dihydroxyacetone kinase regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 1199771..1200328
  • length: 558
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGAAGGAAGTAAAAGAAAGGCTTCCTATGGCATCATCACTCATTACAAAAAAACGGATT
    GCCAAGGCATTTAGAGACCTATTAGCTACTAGAGAATTTGACAAAATCTCCATTGTAGAT
    ATTATGGAATCAGCTGGCATTCGTAGACAGACCTTTTATAATCACTTTCTTGACAAATAT
    GAACTGCTAGACTGGATATTTGAAAATGACTTAACCGAGTATATCACCAATAACTTGGAC
    TTCATTTCGGGCCAAAAACTATTACAAGAATTATTTTTTTATTTCGAACAAGAGCGTGAC
    TTTTATATTCAACTTTTTGATATTCAAGGGCAAAATAACTTCTATGACCACTTTATCAGC
    TACTGTCGCTTGCTTGTATCAAAAATTTTAAGAGAATACGGTCAGATTGATATCGATTCA
    TCTGCTTATACTTGCTTTTTGTTAGACTATCATTCACATGCTCTAGCAGAAATCGTGAAG
    GCTTATGTCAATAAAAAAAGTTCAGTTCCACAACCAGACTTTCTCATCATGACAATTATT
    GGAAAGAGACCACAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    558

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1293 [new locus tag: SPH_RS06260 ]
  • symbol: SPH_1293
  • description: probable dihydroxyacetone kinase regulator
  • length: 185
  • theoretical pI: 6.12434
  • theoretical MW: 22029.2
  • GRAVY: -0.214054

⊟Function[edit | edit source]

  • TIGRFAM:
    probable dihydroxyacetone kinase regulator (TIGR02366; HMM-score: 187.6)
    and 1 more
    Signal transduction Regulatory functions DNA interactions mycofactocin system transcriptional regulator (TIGR03968; HMM-score: 27.2)
  • TheSEED  :
    • Transcriptional regulator, TetR family
  • PFAM:
    TetR_C (CL0174) TetR_C_8; Transcriptional regulator C-terminal region (PF14278; HMM-score: 31.9)
    HTH (CL0123) TetR_N; Bacterial regulatory proteins, tetR family (PF00440; HMM-score: 28.4)
    and 3 more
    HTH_Tnp_1_2; Helix-turn-helix of insertion element transposase (PF13022; HMM-score: 19.7)
    no clan defined CRISPR_Cas2; CRISPR associated protein Cas2 (PF09827; HMM-score: 14.2)
    RRM (CL0221) YlmH_RBD; Putative RNA-binding domain in YlmH (PF17774; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.923
    • Cytoplasmic Membrane Score: 0.0602
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.0161
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002365
    • TAT(Tat/SPI): 0.000256
    • LIPO(Sec/SPII): 0.000296
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKEVKERLPMASSLITKKRIAKAFRDLLATREFDKISIVDIMESAGIRRQTFYNHFLDKYELLDWIFENDLTEYITNNLDFISGQKLLQELFFYFEQERDFYIQLFDIQGQNNFYDHFISYCRLLVSKILREYGQIDIDSSAYTCFLLDYHSHALAEIVKAYVNKKSSVPQPDFLIMTIIGKRPQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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