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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1431 [new locus tag: SPH_RS06915 ]
  • pan locus tag?: PNEUPAN002570000
  • symbol: SPH_1431
  • pan gene symbol?: —
  • synonym:
  • product: HD superfamily phosphohydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1431 [new locus tag: SPH_RS06915 ]
  • symbol: SPH_1431
  • product: HD superfamily phosphohydrolase
  • replicon: chromosome
  • strand: +
  • coordinates: 1327049..1328353
  • length: 1305
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGAACGAAAAAGTATTCCGTGACCCTGTTCACAACTACATCCATGTCAATAATCAAATC
    ATCTATGACTTGATTAATACAAAAGAATTTCAGCGTTTGCGCCGGATCAAACAACTGGGA
    ACTTCCAGTTATACCTTCCACGGTGGAGAACACAGTCGCTTCTCTCACTGTCTAGGAGTC
    TATGAAATTGCACGACGCATCACAGAGATTTTCGAAGAAAAATATCCTGAGGAATGGAAT
    CCTGCCGAGTCTCTCTTGACCATGACCGCTGCTCTCCTACACGACCTTGGGCATGGTGCC
    TACTCCCATACTTTTGAAAATCTCTTTGATACAGACCATGAAGCCATTACTCAGGAGATT
    ATTCAAAATCCTGAGACAGAGATTCACCAAGTCTTGCTACAAGTAGCGCCCGATTTTCCA
    GAGAAAGTTGCCAGTGTCATAGACCATACCTATCCTAACAAGCAGGTCGTGCAGCTCATT
    TCTAGTCAGATTGACGCAGATCGCATGGACTATCTCTTGCGCGACTCCTATTTTACAGGA
    GCATCCTATGGGGAATTTGACCTGACTCGAATCCTCCGAGTCATTCGTCCTATCGAAAAT
    GGTATCGCCTTTCAGCGCAATGGCATGCACGCCATCGAAGACTACGTCCTCAGTCGCTAC
    CAGATGTACATGCAGGTTTATTTCCACCCCGCAACACGCGCCATGGAAGTTCTCCTACAG
    AATCTTCTCAAACGCGCCAAGGAACTCTATCCTGAAGACAAGGACTTCTTTGCACGAACT
    TCTCCACACCTCCTACCTTTCTTTGAAAAAAATGTGACCTTGACTGACTATCTGGCTCTA
    GATGATGGTGTGATGAATACCTACTTTCAACTCTGGATGACCAGTCCTGACAAGATTCTC
    GCAGACTTGTCACAACGCTTTGTCAACCGCAAGGTCTTTAAATCCATTACCTTTTCACAA
    GAAGACCAAGACCAACTCGCTAGCATGAGAAAATTGGTTGAGGACATCGGCTTTGATCCC
    GACTACTATACTGCCATTCATAAGAACTTTGACCTCCCTTATGATATTTACCGTCCCGAA
    TCTGAAAATCCAAGGACACAAATTGAGATTCTACAAAAAAATGGTGAACTGGCAGAACTC
    TCTAGCCTGTCCCCTATCGTCCAATCCCTTGCTGGAAGTCGCCACGGAGATAATCGCTTT
    TATTTCCCGAAAGAAATGTTAGACCAAAACAGCATCTTCGCAAGCATCACCCAGCAATTT
    TTACACTTGATTGAGAACGATCATTTTACCCCATATAAAAACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1305

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1431 [new locus tag: SPH_RS06915 ]
  • symbol: SPH_1431
  • description: HD superfamily phosphohydrolase
  • length: 434
  • theoretical pI: 5.29969
  • theoretical MW: 50852
  • GRAVY: -0.463364

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions putative dGTPase (TIGR01353; EC 3.1.5.1; HMM-score: 27.3)
    and 4 more
    HDIG domain (TIGR00277; HMM-score: 17.8)
    CRISPR-associated endonuclease Cas3-HD (TIGR01596; EC 3.1.-.-; HMM-score: 12.9)
    phosphonate degradation operons associated HDIG domain protein (TIGR03276; HMM-score: 11.4)
    CRISPR-associated helicase Cas3, subtype I-F/YPEST (TIGR02562; HMM-score: 10.9)
  • TheSEED  :
    • Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)
    Nucleosides and Nucleotides Purines Purine conversions  Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)
  • PFAM:
    HD_PDEase (CL0237) HD; HD domain (PF01966; HMM-score: 52.5)
    and 3 more
    no clan defined HD_assoc_2; HD associated region (PF19276; HMM-score: 40.4)
    HD_PDEase (CL0237) PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase (PF00233; HMM-score: 15.3)
    no clan defined CTD9; C-terminal domain 9 of the ABC-three component (ABC-3C) systems (PF20285; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9595
    • Cytoplasmic Membrane Score: 0.0356
    • Cell wall & surface Score: 0.0006
    • Extracellular Score: 0.0044
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.010057
    • TAT(Tat/SPI): 0.000943
    • LIPO(Sec/SPII): 0.000369
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSYTFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYSHTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLISSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLSRYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTDYLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVEDIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAGSRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPYKN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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