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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_1487 [new locus tag: SPH_RS07185 ]
  • pan locus tag?: PNEUPAN002698000
  • symbol: SPH_1487
  • pan gene symbol?: trzA
  • synonym:
  • product: chlorohydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_1487 [new locus tag: SPH_RS07185 ]
  • symbol: SPH_1487
  • product: chlorohydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 1371231..1372787
  • length: 1557
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGAAAATCAAAGAGCAAACTAGGAAGCTAGCCGTAGGTTGCTCAAAGCACAGCTTTGAG
    GTTGTAGATAAGACTGACGAAGTCAGTTCAAAACACTGTTTTGAGGTTGCAGATAGAACT
    GACGAAGTCAGCTCAAAACACTGTTTTGAGGTTGCAGATAGAACTGACGAAGTCAGCTCA
    AAACACTGTTTTGAGGTTGCAGATAGAACTGACGAAGTCAGTAACCACACCTACGGCAAA
    GTGAATCTGAAGTGGTTTGAAGAGAGTACAACTTGTCTTTTAAAAAAGGAGTCTATAATG
    AAAGTCTTTCAGCATGTAAATATCGTGACTTGTGATCAAGATTTCCATGTTTATCTTGAT
    GGAATCTTAGCAGTCAAGGATTCTCAAATCGTCTATGTCGGTCAAGATAAGCCAGCGTTT
    TTAGAGCAAGCTGAGCAGATTATAGACTATCAGGGAGCTTGGATTATGCCTGGTTTGGTC
    AATTGTCACACCCATTCTGCAATGACAGGCCTGAGAGGGATCCGAGATGACAGCAATCTC
    CATGAATGGCTCAATGACTATATCTGGCCAGCAGAATCTGAGTTTACTCCCGACATGACT
    ACCAATGCGGTCAAAGAAGCCCTAACAGAGATGCTCCAGTCAGGAACAACAACCTTTAAC
    GATATGTATAATCCCAATGGTGTGGATATCCAGCAAATTTATCAGGTGGTGAAAACTTCC
    AAGATGCGTTGTTATTTTTCTCCGACTCTCTTTTCTTCAGAGACAGAAACAACTGCTGAG
    ACTATAAGCAGAACTCGATCCATCATAGACGAAATCTTAAAATATAAAAATCCAAATTTC
    AAGGTTATGGTAGCACCTCATTCTCCGTATAGCTGCAGTAGAGACTTGCTGGAAGCGAGT
    TTGGAAATGGCAAAAGAGCTAAATATTCCGCTCCATGTCCATGTGGCGGAGACCAAGGAG
    GAGTCAGGAATTATCCTCAAACGATACGGCAAACGCCCCCTTGCTTTTCTTGAAGAACTG
    GGTTATTTAGATCATCCGTCCGTCTTTGCTCACGGGGTCGAATTAAACGAGAGAGAAATT
    GAACGCTTGGCATCTTCTCAAGTGGCTATCGCCCACAATCCTATCAGTAACCTCAAACTG
    GCATCAGGAATTGCTCCAATTATCCAGCTCCAAAAAGCGGGAGTAGCAGTCGGAATTGCG
    ACTGACTCGGTTGCTTCCAATAACAATCTAGATATGTTTGAGGAAGGAAGGACTGCAGCT
    CTTCTTCAGAAGATGAAAAGTGGGGATGCCAGCCAGTTTCCAATCGAAACAGCTCTCAAG
    GTACTGACAATCGAAGGGGCTAAGGTCCTTGGAATGGAAAATCAGATAGGAAGTCTGGAA
    GTCGGCAAGCAAGCAGATTTTCTGGTCATTCAACCACAAGGGAAAATTCATCTCCAACCT
    CAGGAAAATATGCTGTCTCACCTGGTTTATGCAGTTAAATCTAGTGATGTAGATGATGTT
    TATATCGCCGGAGAACAGGTTGTTAAGCAAGGTCAAGTCCTGACAGTAGAACTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1557

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_1487 [new locus tag: SPH_RS07185 ]
  • symbol: SPH_1487
  • description: chlorohydrolase
  • length: 518
  • theoretical pI: 5.03909
  • theoretical MW: 57878.3
  • GRAVY: -0.265444

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other guanine deaminase (TIGR02967; EC 3.5.4.3; HMM-score: 189.3)
    putative selenium metabolism protein SsnA (TIGR03314; HMM-score: 152.6)
    and 12 more
    Metabolism Energy metabolism Amino acids and amines formiminoglutamate deiminase (TIGR02022; EC 3.5.3.13; HMM-score: 135.1)
    Metabolism Energy metabolism Amino acids and amines imidazolonepropionase (TIGR01224; EC 3.5.2.7; HMM-score: 67.3)
    allantoinase (TIGR03178; EC 3.5.2.5; HMM-score: 43.5)
    Metabolism Energy metabolism Other phosphonate metabolism protein PhnM (TIGR02318; HMM-score: 39.5)
    dihydropyrimidinase (TIGR02033; EC 3.5.2.2; HMM-score: 34.3)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis dihydroorotase, multifunctional complex type (TIGR00857; EC 3.5.2.3; HMM-score: 28.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine deaminase (TIGR01178; EC 3.5.4.2; HMM-score: 27.2)
    Metabolism Central intermediary metabolism Amino sugars N-acetylglucosamine-6-phosphate deacetylase (TIGR00221; EC 3.5.1.25; HMM-score: 25.5)
    formylmethanofuran dehydrogenase subunit A (TIGR03121; EC 1.2.99.5; HMM-score: 25.3)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides beta-aspartyl peptidase (TIGR01975; EC 3.4.19.5; HMM-score: 23.1)
    Metabolism Central intermediary metabolism Nitrogen metabolism urease, alpha subunit (TIGR01792; EC 3.5.1.5; HMM-score: 17.3)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions conjugative transfer region lipoprotein, TIGR03751 family (TIGR03751; HMM-score: 14.1)
  • TheSEED  :
    • Methylthioadenosine deaminase
    • S-adenosylhomocysteine deaminase (EC 3.5.4.28)
    RNA Metabolism RNA processing and modification tRNA modification Archaea  Methylthioadenosine deaminase
  • PFAM:
    Amidohydrolase (CL0034) Amidohydro_1; Amidohydrolase family (PF01979; HMM-score: 231.5)
    and 3 more
    Amidohydro_3; Amidohydrolase family (PF07969; HMM-score: 82.3)
    TatD_DNase; TatD related DNase (PF01026; HMM-score: 23.9)
    Phage_TACs (CL0567) Phage_TAC_8; Phage tail assembly chaperone protein Gp14 ()A118 (PF10666; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014803
    • TAT(Tat/SPI): 0.000784
    • LIPO(Sec/SPII): 0.002615
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIKEQTRKLAVGCSKHSFEVVDKTDEVSSKHCFEVADRTDEVSSKHCFEVADRTDEVSSKHCFEVADRTDEVSNHTYGKVNLKWFEESTTCLLKKESIMKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQAEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTTNAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTAETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAETKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPISNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQFPIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYAVKSSDVDDVYIAGEQVVKQGQVLTVEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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