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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Hungary19A-6
- locus tag: SPH_2319 [new locus tag: SPH_RS11365 ]
- pan locus tag?: PNEUPAN003678000
- symbol: SPH_2319
- pan gene symbol?: tktC
- synonym:
- product: transketolase, C- subunit
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPH_2319 [new locus tag: SPH_RS11365 ]
- symbol: SPH_2319
- product: transketolase, C- subunit
- replicon: chromosome
- strand: -
- coordinates: 2123879..2124811
- length: 933
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000936 (2123879..2124811) NCBI
- BioCyc: see SPH_RS11365
- MicrobesOnline: 5697138 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1957 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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901ATGATGAGAAGTACGAAAGAATTACGGCATGTATATAGAGACTTCCTTTTAGAGGCTAAT
CAAAGTTATTCTGATATAGTAGTCTTAGAAGCCGATTTGTCAAGTTCGATGGCTACTCAT
AATCTTGAAAAGGACTTCGGAGACCGTTATGTGAATGTTGGGATTATGGAAGCAGAAATG
GTCGGCCTTGCAGCAGGCTTGTCTATTCAGGGGTTTAGACCTTATCTTCATACATTTGGT
CCTTTTGCTTCACGAAGAGTATTTGATCAATTATTTATTTCTCTTGGATACGCACAATTG
GATGCCACTGTGATTGGATCAGATGCAGGAGTAACGGCAGAGATGAATGGTGGAACACAT
ATGCCATTTGAAGAAATCGGCTTGTTACGTTTAATTCCTAAATCAATCATTTTTGAAGCA
ACTGATGATATCCAATTTCGTGAAATATTGAACCAGACATTAGACTTAAAAGGACTAAAA
TATATTCGAACAATTAGAAAAGCTCCAGAGGCTGTATATCAAGGTGGAGAAGATTTTTCT
AAAGGCTACATTGAGTTAAGACACGGTGAAGATGTTGTAATAGTTGCTTCTGGCATAATG
GTTGCTCCAAGTATTCGAGTTGCAGATGAACTGTCTAAATTAGGTTATTCAGTAGGTGTG
ATAGATTTATTTAGAATCAAACCGATACCAGAACAGATAAAAACAATGTTAAGTGGAAAA
ACTGTATTTACTGTAGAAAACCACAATCAGATAGGTGGAATTGGCAGTGCTTTATGTGAA
TTATTCTCTGATGATGGAATAACAAAAATTCATCGGATGGGTGTTCAAGAAAGATTTGGT
CAAGTAGGGAAAATGGATTATCTTCTTAATGAGTATGGTTTGAGTGAATCGAATATAAAA
GAGAAGGTTCTAGAAATTTATAATGCAAGATAG60
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933
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPH_2319 [new locus tag: SPH_RS11365 ]
- symbol: SPH_2319
- description: transketolase, C- subunit
- length: 310
- theoretical pI: 5.10158
- theoretical MW: 34544.4
- GRAVY: -0.0525806
⊟Function[edit | edit source]
- TIGRFAM: Biosynthesis of cofactors, prosthetic groups, and carriers Other 1-deoxy-D-xylulose-5-phosphate synthase (TIGR00204; EC 2.2.1.7; HMM-score: 121.6)Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine 1-deoxy-D-xylulose-5-phosphate synthase (TIGR00204; EC 2.2.1.7; HMM-score: 121.6)Biosynthesis of cofactors, prosthetic groups, and carriers Pyridoxine 1-deoxy-D-xylulose-5-phosphate synthase (TIGR00204; EC 2.2.1.7; HMM-score: 121.6)and 2 moreEnergy metabolism Pentose phosphate pathway transketolase (TIGR00232; EC 2.2.1.1; HMM-score: 47.2)2-oxoacid:acceptor oxidoreductase, alpha subunit (TIGR03710; HMM-score: 14.7)
- TheSEED :
- Transketolase, C-terminal section (EC 2.2.1.1)
- PFAM: TKC_like (CL0591) Transketolase_C; Transketolase, C-terminal domain (PF02780; HMM-score: 74.1)THDP-binding (CL0254) Transket_pyr; Transketolase, pyrimidine binding domain (PF02779; HMM-score: 73.5)and 1 moreTKC_like (CL0591) PFOR_II; Pyruvate:ferredoxin oxidoreductase core domain II (PF17147; HMM-score: 24.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005754
- TAT(Tat/SPI): 0.001354
- LIPO(Sec/SPII): 0.000462
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEKDFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDATVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLKYIRTIRKAPEAVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSVGVIDLFRIKPIPEQIKTMLSGKTVFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1957 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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