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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 10-MAR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS00525 [old locus tag: SPH_0113 ]
  • pan locus tag?: PNEUPAN000626000
  • symbol: SPH_RS00525
  • pan gene symbol?: —
  • synonym:
  • product: tape measure protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS00525 [old locus tag: SPH_0113 ]
  • symbol: SPH_RS00525
  • product: tape measure protein
  • replicon: chromosome
  • strand: +
  • coordinates: 83175..86456
  • length: 3282
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (83175..86456) NCBI
  • BioCyc: SPH_RS00525 BioCyc
  • MicrobesOnline: see SPH_0113
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    ATGACTGATGGAAAAGTGACCATCGTTGTCGATGTGGATGGTAATAAAGTCAAGGTTCTA
    AACGATGAGTTAGATAAAACGGCACAGAAAGGTGACAGAGGGAGCGATTCTCTAAAGAAG
    TTTGCGATTGGTGGTGCTGCTTTTAAACTGGCATCTAAAGCGGTAGATCTTCTAACAGAT
    TCCTTGGGCGGAGCGATTCAACGTTTTGATACTCTTGAAAGTTATCCAAGAGTGATGCAA
    GCGATGGGGCATAGTACAGAAGATGTCACGCGCTCAACTAAGAAACTAGCGGCAGGTATT
    GAGGGTTTGCCTACGACTTTAAATGAAGTGGTAGGCACAGCTCAACGCCTTACCTCGATT
    ACTGGCGATATAAACAAATCAACAGATTTAACACTTGCTCTTAATAATGCCTTTCTTGCC
    TCTGGATCTTCTAGTGCTGATGCAAGCCGTGGTTTACAACAGTTCAGTCAGATGTTATCA
    ACTGGTAAGGTTGACATGCAAAGTTGGAAAACGTTACAGGAAACCATGCCTTATGCTTTG
    CAAAAGACTGCTGAATCATTCGGTTTTGCTGGCCAATCTGCTCAGAATGATTTCTATTCT
    GCATTAAAAGAAGGGCGTATCACTTTCAACCAATTTTCAAGCAAATTGGTTGAATTGAAT
    GGTGGCGTTGGTGGTTTTGCAGAACTTGCTAAAACTAACAGTAAAGGGATCCAGACATCT
    TTTGGGAACTTAAAGAATGCAGTTGTTAAAGGTGTAGCTAATACTATCAAGGCTCTTGAC
    GATTTAACAAAGGCAGCAACAGGTAAGACGATTGCTGAGAACTTCGATGCATTGAAAGTA
    ATCATCAATGCGGCTTTTGGTGTTATTGTCAACGTAATTAAAGCTAGCACACCTGTTTTT
    CAGACTTTGTTTAGTATTTTGGGTACTGGAGCTTCTGTAATCTCATCTTTGACACCAGTT
    ATTATTAGTTTGGTTTCTGCTTTGGTGGCTATGCGTGCCGCTAATGAAGCTATAACAGCA
    ACAAAAAACTTAATTAATTCCTGGCAGACATTCAAAACAACAGCCACAGGAGCGATTCAG
    ATCATCAATCTAATGACAGCTGCCCAAGCTACTTGTGGCTCAGTAACAAAGGCTCAAATG
    GTTGCTAACTTGGCCAATAACGGAGCTTTGACAGCATCCAATTTGCTTTATGGGGTTCTA
    ACTGGCTCTATCAGCTTACAGACTGCTGCTACTATTGCTGCGACTGCTGCAACTACCGCA
    TTTAAAGCAGCACTGACCGCTTTAACTGGCCCGATTGGTTTGGTTGTTGCTGGTGTAGGT
    CTTGCTGTTGGGGCATTGGTAGGGTTGTGGCAATGGCTAACTGCCGAGAGTGAGGAGACC
    AAACGCCTCAAATCAGAACAAGAGGAGTTAGTCAAGAGTACGGATCAATTAACGGATTCT
    GTTAAACAAAGCGCAAAAGAACGTCAAAAAAATCTTGAGTCTGTAAAAGGTAATACAGAA
    TCTTACCAAAAATTGGCTGACGAAATTGTCCAGTTATCACAAAAGACAAATAAGACAGCA
    GCAGACAAGAAAAATCTCAAGAAAAAGATTGATGCTTTAAATGCCTCTGTTAGTGGATTG
    AATCTAGTCTATGACAAAAACACTGATTTTTTGTCTCATAACAATGACCAAATCAAAGCT
    CGTATCTCAGCGATGGAGGCAGAATCAACATGGGAGACATCCCAGAAGAACCTGCTTGAT
    ATCGAACAAAAGCGTGCTGAAATTGGCGAACAGCTAAAGCAGATAGCTGAACAACGCAAA
    AAATGGAATGAAGAATCCAATGTTAGCGATAGTGTCCGTAAAGAAAGACTGCAAGAACTC
    AACGACAAGGAAACTGAGCTAAAAAATACTCAGACAGAATTGCAAACTGAGTACGAAAAA
    ACGTCTCAAGTTCAACAGGCGGCATCTGAAGCGATGGCTGCTGCTGCCGAAAATGGATCT
    AATCGACAAGTTATATCATACGAAGGTATGTCTAAAGCTCAACAAAAAGCGGTTGATGAT
    ATGCGCTCTAAATACAATGAGTTGCTTGAAACCACAACGAACATGTTTGATCAGATACAA
    ATGAAGTCAGCTATTAGTGTCGATGAAATGATTGCCAACCTCCAAAAAAACCAAGAGGCG
    GTTAATAATTGGGCAACAAACCTCAATACATTGGCCGAACGTGGGGTAAACGAGGGGATT
    TTAGCTAAATTGCAAGCGATGGGGCCTCAAGGTGGGTTGTACGTTCAAGAACTCGTTAAT
    GCATCAGACGAAAAATTGGCAACATTGAACGAAGTCTTTACTCAAGGTGGTGAGTCAGCT
    ATGAATGGCTTAACTGCTGGTATGGATACGGGTGCTTTGGGTATCACAGACAAAATCAAG
    GGTATTGTACAAAGTCAAGTTTCAAGCTTACAAGAGGAAATTGCAGCTGCTGACTTCCCT
    GAAAAAGGGAAAAATATTCCTGAAGGTGTTGGTGATGGTATAAAAGCTGGAGCTGAAATT
    GCAAGTGAAGCTTCTAAAAACATGGCAAATGACATAAAAGAATCCTTTACAAGTGAAATG
    GATATCAATTCCCCATCTCGTGTTTTCAATGAGTATGGTGGTTTTATCACTACTGGTTTA
    GCTGAGGGGGTAGATAAAGGTACCAATCAACCTGTATCATCTGTTACTAATTTAGCCAAT
    CAAATTAAGAAACCATTTGATAGTCTGCAGAGTGATTTCACGTACATTGGTGAAATGGCG
    ATGTCTGGTCTTAATGCAGGGCTTTGGAGTGGCTCTAGTTCTGTTATGGCAACAGCTAAT
    TCAATTGCTGAAAGGGTAAAAGCGACCATCAAGAGCGCACTAGATATTCACTCGCCATCT
    AGAGCAATGCGTGATGAAGTCGGACGTTTCATTCCTCAAGGTATCGCTGTTGGTATTGAA
    GCAGATGCAGGGGTTGTTGAAAAATCAATGTTGCGATTAAAAGAAAGCATGATGATTGAT
    ACTAGACCAGAAATTGCACTTGGCTTAAACAAGAAACTAGGTGCTCAAGTGACTGTTAAA
    CAAAGTAGTAAGCAGACAATAGCTGAAAAAATCAAAGTTACTATGGACAAGTCTAGCGAA
    CTACTCAAAAAAGCCCTGGATGTAGCTGAGACGGCCGTTAGACGACCAAATGAAATGTAC
    TTAAACGATGGTACTTTAGTCGCCAAAACAGGCGATAAATTTGCTAAATATCAATCGGAA
    CAACTAAGACGAGATAATAGGATGAAAGGGGTATTGTCATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
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    720
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    840
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    1020
    1080
    1140
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    1260
    1320
    1380
    1440
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    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3282

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS00525 [old locus tag: SPH_0113 ]
  • symbol: SPH_RS00525
  • description: tape measure protein
  • length: 1093
  • theoretical pI: 5.59327
  • theoretical MW: 116964
  • GRAVY: -0.273833

⊟Function[edit | edit source]

  • TIGRFAM:
    tape measure domain (TIGR02675; HMM-score: 79.1)
    and 5 more
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 17.9)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 17.9)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 9.1)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 9.1)
    helix-rich protein (TIGR04523; HMM-score: 6.3)
  • TheSEED: see SPH_0113
  • PFAM:
    no clan defined TMP_3; Tape measure protein (PF20155; HMM-score: 128)
    and 3 more
    DUF2681; Protein of unknown function (DUF2681) (PF10883; HMM-score: 14.7)
    LapA_dom; Lipopolysaccharide assembly protein A domain (PF06305; HMM-score: 12.3)
    TnpW; Transposon-encoded protein TnpW (PF14202; HMM-score: 8.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 9.35
    • Cellwall Score: 0.32
    • Extracellular Score: 0.32
    • Internal Helices: 4
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007358
    • TAT(Tat/SPI): 0.002101
    • LIPO(Sec/SPII): 0.000658
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTDGKVTIVVDVDGNKVKVLNDELDKTAQKGDRGSDSLKKFAIGGAAFKLASKAVDLLTDSLGGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEGLPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLQQFSQMLSTGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSSKLVELNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATGKTIAENFDALKVIINAAFGVIVNVIKASTPVFQTLFSILGTGASVISSLTPVIISLVSALVAMRAANEAITATKNLINSWQTFKTTATGAIQIINLMTAAQATCGSVTKAQMVANLANNGALTASNLLYGVLTGSISLQTAATIAATAATTAFKAALTALTGPIGLVVAGVGLAVGALVGLWQWLTAESEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTESYQKLADEIVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLVYDKNTDFLSHNNDQIKARISAMEAESTWETSQKNLLDIEQKRAEIGEQLKQIAEQRKKWNEESNVSDSVRKERLQELNDKETELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVISYEGMSKAQQKAVDDMRSKYNELLETTTNMFDQIQMKSAISVDEMIANLQKNQEAVNNWATNLNTLAERGVNEGILAKLQAMGPQGGLYVQELVNASDEKLATLNEVFTQGGESAMNGLTAGMDTGALGITDKIKGIVQSQVSSLQEEIAAADFPEKGKNIPEGVGDGIKAGAEIASEASKNMANDIKESFTSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFDSLQSDFTYIGEMAMSGLNAGLWSGSSSVMATANSIAERVKATIKSALDIHSPSRAMRDEVGRFIPQGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSSKQTIAEKIKVTMDKSSELLKKALDVAETAVRRPNEMYLNDGTLVAKTGDKFAKYQSEQLRRDNRMKGVLS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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