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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS02245 [old locus tag: SPH_0462 ]
  • pan locus tag?: PNEUPAN000305000
  • symbol: SPH_RS02245
  • pan gene symbol?: cpsH
  • synonym:
  • product: glycosyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS02245 [old locus tag: SPH_0462 ]
  • symbol: SPH_RS02245
  • product: glycosyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 411427..412305
  • length: 879
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (411427..412305) NCBI
  • BioCyc: SPH_RS02245 BioCyc
  • MicrobesOnline: see SPH_0462
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    TTGTTTTGTTATATTATTTTGCATTACAAAGTCTTAGAGGAAACTATTTCTTGTGTTAAA
    TCAATAAAAGAAGGCAATTCCAATACAAAGCAGATCGTTATTATTGATAATTTTTCTAAT
    AACGGTACGGGTGAAAAACTACAAGAGCTGTATGAGTCAGATTCAGAGATTGATGTCTTG
    ATTAACCATGAAAATGCTGGTTTCGCTCGAGGTAATAATGTAGCATATCAGTTTGCTAAG
    GAAAAGTACAAACCTGATTTTATGGTTATCATGAATAATGATATTGAGATAGAAACAGAA
    GAGTTTGAAAAAATCGTGACAGATATCTATCGGAAGGAAAAATTCCATTTGTTAGGACCA
    GATATCTTTTCGACGACGTATCAGCTTCACCAAAACCCAAAACGGTTGACGCATTATACT
    TATGAAGAGGTTAAGGCTCTCAATGAAAAATTTAAGAAAGGGAGCCAAGTTAGTCTAGCA
    TTAAAAATTAAATGTTGGTTGAAGTCTAGTAAAGTTCTTCGGACAGCAATCTATCAAAAT
    AGGCGTAAAAAGAAATCAGTAGACTATAGAAAACAGGTAGAAAACCCAATTCTTCATGGT
    TCGTTTATTGTATATTCTAGAGATTTTATTGAGAAAGAGGAGTATGCTTTTAATCCCAAT
    ACCTTCTTCTATTATGAAACAGAGATATTAGATTATGAAGCTGAGTTAAAAGGATATAAG
    AGAATTTATACACCGAAGATTAAGGTCTTGCACCATCAAAATGTTGCAACCAATCAAGTC
    TATACAAACTTAGTAGAAAAAACCTTGTTTTCAAACAAATGCAACTTTGAATCCACTAGT
    TATTTTTTGAAGTTGATGAAAGAAAACGAGGGTGTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    879

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS02245 [old locus tag: SPH_0462 ]
  • symbol: SPH_RS02245
  • description: glycosyltransferase
  • length: 292
  • theoretical pI: 8.25577
  • theoretical MW: 34509.1
  • GRAVY: -0.583562

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.-.-?  ExPASy
  • TIGRFAM:
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides rhamnosyltransferase (TIGR01556; EC 2.4.1.-; HMM-score: 23.6)
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 23.2)
    and 1 more
    UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03992; EC 2.3.1.157,2.7.7.23; HMM-score: 14.9)
  • TheSEED: see SPH_0462
  • PFAM:
    GT-A (CL0110) Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 48.9)
    and 2 more
    NTP_transferase; Nucleotidyl transferase (PF00483; HMM-score: 16.6)
    CheY (CL0304) NARF; Nucleotidyltransferase-Associated Rossmannoid Fold (PF20299; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.1279
    • Cytoplasmic Membrane Score: 0.8557
    • Cell wall & surface Score: 0.0004
    • Extracellular Score: 0.016
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013456
    • TAT(Tat/SPI): 0.000372
    • LIPO(Sec/SPII): 0.050611
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MFCYIILHYKVLEETISCVKSIKEGNSNTKQIVIIDNFSNNGTGEKLQELYESDSEIDVLINHENAGFARGNNVAYQFAKEKYKPDFMVIMNNDIEIETEEFEKIVTDIYRKEKFHLLGPDIFSTTYQLHQNPKRLTHYTYEEVKALNEKFKKGSQVSLALKIKCWLKSSKVLRTAIYQNRRKKKSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFNPNTFFYYETEILDYEAELKGYKRIYTPKIKVLHHQNVATNQVYTNLVEKTLFSNKCNFESTSYFLKLMKENEGV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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