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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS03345 [old locus tag: SPH_0688 ]
  • pan locus tag?: PNEUPAN001486000
  • symbol: SPH_RS03345
  • pan gene symbol?: mshD_1
  • synonym:
  • product: GNAT family N-acetyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS03345 [old locus tag: SPH_0688 ]
  • symbol: SPH_RS03345
  • product: GNAT family N-acetyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 635355..636239
  • length: 885
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATTCAAGCAAGAAACAAGTTAAGCCAAGAGGAGCTATCTGAGGCGAAAAAACTAATT
    AACTATTGTCAAAACTATGACGGTACCTATCGTGATCCCTATCTCTCTAACATGCTTAAT
    TTTGACCCAAACATGCCCGCCTTTTTCCTTTATTATGAAAAAGGCGAACTTGTTGGTTTA
    TTAACTGTCTATGCAGATGATCAAGATGTGGAAGTGACGATACTGGTTCATCCAGATTAT
    CGCCGTCAGGGAATTGCGCGTGTATTGTTTACTAGTTTTGAGAAAGAAACGGCTGCTTTT
    TCTATTCGTTCAGTGACTTTTCAGACAGAGCGTATTTTTCTAGACCGCCATCCTGATTTT
    GTTAGTAACTGGGGATTGGTCGAGGATGAAGAGACAGAAACCTGGTTAGGTAAGGATAGA
    AAACCTTATCCGTTAGCAAAGCTTTCCAATCTTGAAGTTTTGTTAGCAGATAGTTCGTAT
    CAGGAGCAAATTAGTCAGTTAAAATTTCAGGCATTCTCAGAGGAACATGAGTCTAGAGAG
    ATTGTGGATAGATATGTCGCTGAGGCTCTGAAAGATCCAGAAAGTCGCCTATATATTTTA
    TTAAAAAATAGTCAGGTTATTGGAACTTGCACGGTAGATTTATCGACTAATACGAATTAC
    TTCTACGGTTTAGCAATATCTGAATCTGAACGTGGGAAAGGCTATGGAAGTTATTTAGCA
    AAATCCCTCGTCAACCAACTCATTGAGCAAAATAACAAGGAATTTCAGATTGCAGTGGAA
    GATAGCAATGTAGGTGCCAAACGTTTATATGAAAAAATTGGCTTTGTCAAACAGACTCAG
    GTGGTTTATCTGAATGAGAAAGGAGCAAGGGATTCCGAAGTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    885

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS03345 [old locus tag: SPH_0688 ]
  • symbol: SPH_RS03345
  • description: GNAT family N-acetyltransferase
  • length: 294
  • theoretical pI: 4.59153
  • theoretical MW: 33914.8
  • GRAVY: -0.482313

⊟Function[edit | edit source]

  • reaction:
    EC 2.3.1.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 68.1)
    and 6 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 45.3)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 27.3)
    putative beta-lysine N-acetyltransferase (TIGR03827; EC 2.3.1.-; HMM-score: 22.8)
    GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 22.2)
    Cellular processes Cellular processes Adaptations to atypical conditions diaminobutyrate acetyltransferase (TIGR02406; EC 2.3.1.178; HMM-score: 19.9)
    Cellular processes Cellular processes Toxin production and resistance aminoglycoside N(6')-acetyltransferase, AacA4 family (TIGR04431; EC 2.3.1.82; HMM-score: 19.8)
  • TheSEED: see SPH_0688
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 85.1)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 77.1)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 70.8)
    and 12 more
    FR47; FR47-like protein (PF08445; HMM-score: 46.9)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 44.6)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 38.2)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 27.6)
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 25.7)
    GNAT_acetyltran; GNAT acetyltransferase (PF12746; HMM-score: 22.1)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 19.8)
    Acetyltransf_18; Acetyltransferase (GNAT) domain (PF18014; HMM-score: 19.1)
    no clan defined Germane; Sporulation and spore germination (PF10646; HMM-score: 16.4)
    SopA; SopA-like central domain (PF13981; HMM-score: 14.5)
    Acetyltrans (CL0257) Acetyltransf_13; ESCO1/2 acetyl-transferase (PF13880; HMM-score: 14.2)
    Acetyltransf_6; Acetyltransferase (GNAT) domain (PF13480; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9832
    • Cytoplasmic Membrane Score: 0.0029
    • Cell wall & surface Score: 0.0056
    • Extracellular Score: 0.0083
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007111
    • TAT(Tat/SPI): 0.000254
    • LIPO(Sec/SPII): 0.003172
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIQARNKLSQEELSEAKKLINYCQNYDGTYRDPYLSNMLNFDPNMPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPDYRRQGIARVLFTSFEKETAAFSIRSVTFQTERIFLDRHPDFVSNWGLVEDEETETWLGKDRKPYPLAKLSNLEVLLADSSYQEQISQLKFQAFSEEHESREIVDRYVAEALKDPESRLYILLKNSQVIGTCTVDLSTNTNYFYGLAISESERGKGYGSYLAKSLVNQLIEQNNKEFQIAVEDSNVGAKRLYEKIGFVKQTQVVYLNEKGARDSEV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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