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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 10-MAR-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Hungary19A-6
- locus tag: SPH_RS04615 [old locus tag: SPH_0955 ]
- pan locus tag?: PNEUPAN001833000
- symbol: SPH_RS04615
- pan gene symbol?: ilvE
- synonym:
- product: branched-chain amino acid aminotransferase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPH_RS04615 [old locus tag: SPH_0955 ]
- symbol: SPH_RS04615
- product: branched-chain amino acid aminotransferase
- replicon: chromosome
- strand: +
- coordinates: 881137..882159
- length: 1023
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_010380 (881137..882159) NCBI
- BioCyc: SPH_RS04615 BioCyc
- MicrobesOnline: see SPH_0955
- PneumoBrowse for strain D39V: SPV_0749 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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1021ATGACAGTAACGATTGATTGGGAAAACCTCGGTTTTTCCTATATGAAATTACCTTATCGC
TATCTTGCTCATTTCAAAAATGGACAATGGGATCAAGGAGAGCTTACAGAGGATGCAACT
TTGCATATTTCAGAGTCTTCTCCAAGTCTTCACTATGGACAACAAGCATTTGAAGGTTTG
AAAGCTTATCGTACTAAGGATGGCAGTGTTCAACTGTTCCGTCCTGATGAAAATGCTAAA
CGCCTGCAACGTACATGTGACCGTCTCTTGATGCCACAAGTTCCGACAGACATGTTTGTA
GAAGCTTGTAAAGCAGTTGTCCGTGCGAATGAAGAATACGTACCACCATACGGAATAGGT
GGAACTTTATATCTTCGCCCTCTTTTGATTGGTGTCGGAGATATTATCGGGGTAAAACCG
GCAGAAGAGTACATTTTCACCATCTTTGCTATGCCAGTTGGAAATTACTTTAAAGGTGGT
TTGGTCCCAACCAACTTCTTGATTCAGGATGAGTACGACCGTGCAGCACCAAATGGTACA
GGTGCGGCTAAGGTTGGTGGAAACTATGCTGCAAGTCTCTTACCAGGAAAAATGGCCAAG
TCACGCCATTTCTCAGATGTTATCTATCTGGACCCATCAACTCATACAAAGATTGAAGAA
GTCGGATCAGCTAATTTCTTTGGAATTACAGCTGATAATGAATTTGTAACACCATTGAGT
CCATCTATCTTGCCATCTATTACCAAGTATTCCTTGCTTTATTTGGCAGAACATCGCTTG
GGATTAACTCCTATTGAGGGTGATGTTCCAATTGATAATCTTGACCGTTTTGTAGAGGCA
GGTGCCTGTGGTACAGCAGCGGTTATTTCTCCAATTGGAGGTATTCAACATGGTGATGAT
TTCCATGTATTCTATAGTGAAACAGAAGTAGGTCCTGTGACGCGTAAATTATATAATGAA
TTGACGGGTATTCAGTTTGGCGATATTGAAGCGCCAGAAGGTTGGATTGTAAAAGTAGAT
TAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPH_RS04615 [old locus tag: SPH_0955 ]
- symbol: SPH_RS04615
- description: branched-chain amino acid aminotransferase
- length: 340
- theoretical pI: 4.72126
- theoretical MW: 37485.2
- GRAVY: -0.148529
⊟Function[edit | edit source]
- reaction: EC 2.6.1.42? ExPASyBranched-chain-amino-acid transaminase L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
- TIGRFAM: Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01123; EC 2.6.1.42; HMM-score: 446.5)and 3 moreAmino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01122; EC 2.6.1.42; HMM-score: 99.9)Biosynthesis of cofactors, prosthetic groups, and carriers Folic acid aminodeoxychorismate lyase (TIGR03461; EC 4.1.3.38; HMM-score: 16.7)Energy metabolism Amino acids and amines D-amino-acid transaminase (TIGR01121; EC 2.6.1.21; HMM-score: 14.4)
- TheSEED: see SPH_0955
- PFAM: no clan defined Aminotran_4; Amino-transferase class IV (PF01063; HMM-score: 109.2)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.005728
- TAT(Tat/SPI): 0.000279
- LIPO(Sec/SPII): 0.000739
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHISESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEACKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGGLVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKIEEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDRFVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEGWIVKVD
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: parC > SPH_RS04615 > SPH_RS04620 > SPH_RS04625 > SPH_RS04630 > pcp
⊟Regulation[edit | edit source]
- regulator: CodY see SPH_0955
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0749 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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