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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 02-APR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hu15
  • locus tag: SPNHU15_RS04210 [old locus tag: SPNHU15_00903 ]
  • pan locus tag?: PNEUPAN001833000
  • symbol: SPNHU15_RS04210
  • pan gene symbol?: ilvE
  • synonym:
  • product: branched-chain amino acid aminotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNHU15_RS04210 [old locus tag: SPNHU15_00903 ]
  • symbol: SPNHU15_RS04210
  • product: branched-chain amino acid aminotransferase
  • replicon: chromosome
  • strand: +
  • coordinates: <848278..849108
  • length: 831
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP020551 <848278..849108 NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0749 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ACTAAGGATGGCAGTGTTCAACTGTTCCGTCCTGATGAAAATGCTAAACGCCTGCAACGT
    ACATGTGACCGTCTCTTGATGCCACAAGTTCCGACAGACATGTTTGTAGAAGCTTGTAAA
    GCAGTTGTCCGTGCGAATGAAGAATACGTACCACCATACGGAATAGGTGGAACTTTATAT
    CTTCGCCCTCTTTTGATTGGTGTCGGAGATATTATCGGGGTAAAACCGGCAGAAGAGTAC
    ATTTTCACCATCTTTGCTATGCCAGTTGGAAATTACTTTAAAGGTGGTTTGGTCCCAACC
    AACTTCTTGATTCAGGATGAGTACGACCGTGCAGCACCAAATGGTACAGGTGCGGCTAAG
    GTTGGTGGAAACTATGCTGCAAGTCTCTTACCAGGAAAAATGGCCAAGTCACGCCATTTC
    TCAGATGTTATCTATCTGGACCCATCAACTCATACAAAGATTGAAGAAGTCGGATCAGCT
    AATTTCTTTGGAATTACAGCTGATAATGAATTTGTAACACCATTGAGTCCATCTATCTTG
    CCATCTATTACCAAGTATTCCTTGCTTTATTTGGCAGAACATCGCTTGGGATTAACTCCT
    ATTGAGGGTGATGTTCCAATTGATAATCTTGACCGTTTTGTAGAGGCAGGTGCCTGTGGT
    ACAGCAGCGGTTATTTCTCCAATTGGAGGTATTCAACATGGTGATGATTTCCATGTATTC
    TATAGTGAAACAGAAGTAGGTCCTGTGACGCGTAAATTATATAATGAATTGACGGGTATT
    CAGTTTGGCGATATTGAAGCGCCAGAAGGTTGGATTGTAAAAGTAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    831

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNHU15_RS04210 [old locus tag: SPNHU15_00903 ]
  • symbol: SPNHU15_RS04210
  • description: branched-chain amino acid aminotransferase
  • length: 276
  • theoretical pI: 4.61365
  • theoretical MW: 30032
  • GRAVY: -0.0365942

⊟Function[edit | edit source]

  • reaction:
    EC 2.6.1.42?  ExPASy
    Branched-chain-amino-acid transaminase L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01123; EC 2.6.1.42; HMM-score: 384.7)
    and 2 more
    Metabolism Amino acid biosynthesis Pyruvate family branched-chain amino acid aminotransferase (TIGR01122; EC 2.6.1.42; HMM-score: 68.1)
    Metabolism Energy metabolism Amino acids and amines D-amino-acid transaminase (TIGR01121; EC 2.6.1.21; HMM-score: 13.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Aminotran_4; Amino-transferase class IV (PF01063; HMM-score: 102.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014953
    • TAT(Tat/SPI): 0.000914
    • LIPO(Sec/SPII): 0.003425
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_208941181 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • TKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEACKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGGLVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKIEEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDRFVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEGWIVKVD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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