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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_RS10055 [old locus tag: SPH_2057 ]
  • pan locus tag?: PNEUPAN003511000
  • symbol: SPH_RS10055
  • pan gene symbol?: —
  • synonym:
  • product: LiaF transmembrane domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_RS10055 [old locus tag: SPH_2057 ]
  • symbol: SPH_RS10055
  • product: LiaF transmembrane domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1896761..1897435
  • length: 675
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_010380 (1896761..1897435) NCBI
  • BioCyc: SPH_RS10055 BioCyc
  • MicrobesOnline: see SPH_2057
  • PneumoBrowse for strain D39V: SPV_1717 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAAAAAGAAAGCATTTGGTATTGTGTTACTTGTACTAGCAGCTTTAATATTAGTACAA
    GGAAATTTTGGAATCCCTTCTCTAGGAGGGCACATTTGGCCCTTGATTGGTATTGCTTTT
    TTTGCCTACCAATCAGTTGGAGCTTTGTTGCGTCGCCACTTAACTTCAGCCTCTTTTACA
    GCTCTAGTATCCTTAATGATTGCTAACCACTTTTATGGCATTTTACCGATTCCAAACCAG
    ACACTAATCTGGGCAGGAGTTCTAATCGTTCTCGGAGTAAATATGTTGACTCATTCTAAC
    AGAACTTGGAATGGGAAAAAATGGTGGTATGATGGTGAAAAAAACATTCTTATAGATAAG
    GAAGTTGCTTTTGGGACAGGGACTTTCTACAAGCAAGACCAAGAATTGGTAGAAGACCAA
    GTAGAAGTTGGTTTTGGCAATGCAAAAATCTACTATGACAATGCAGAGATGTTAGGTGAT
    TTTGCAACTTTAAATATTGAAGTAGCTTTTGGTAATGCAACTGTCTATGTTCCGCAACAC
    TGGCGTGTCGATTTGAAAGTAGAAACATCCTTTGGTACAGCCAAGGCGGACGCTCCTGTA
    GCGCCAACAAGCAAAACCTTGATTATTCGTGGAGACGTGGCCTTTGGGAAGTTGGAGCTT
    GTCTACGTTAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    675

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_RS10055 [old locus tag: SPH_2057 ]
  • symbol: SPH_RS10055
  • description: LiaF transmembrane domain-containing protein
  • length: 224
  • theoretical pI: 8.73551
  • theoretical MW: 24705.6
  • GRAVY: 0.319196

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly protein SufB (TIGR01980; HMM-score: 10.6)
  • TheSEED: see SPH_2057
  • PFAM:
    Pec_lyase-like (CL0268) DUF2154; Cell wall-active antibiotics response 4TMS YvqF (PF09922; HMM-score: 27)
    and 1 more
    no clan defined DUF5668; Domain of unknown function (DUF5668) (PF18917; HMM-score: 8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 9.35
    • Cellwall Score: 0.32
    • Extracellular Score: 0.32
    • Internal Helices: 4
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.205254
    • TAT(Tat/SPI): 0.0009
    • LIPO(Sec/SPII): 0.151141
  • predicted transmembrane helices (TMHMM): 3

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQSVGALLRRHLTSASFTALVSLMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRTWNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGDFATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKLELVYVK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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