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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 10-MAR-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae Hungary19A-6
- locus tag: SPH_RS13570
- pan locus tag?: PNEUPAN002272000
- symbol: SPH_RS13570
- pan gene symbol?: serB
- synonym:
- product: HAD-IB family phosphatase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPH_RS13570
- symbol: SPH_RS13570
- product: HAD-IB family phosphatase
- replicon: chromosome
- strand: +
- coordinates: 1119248..1119619
- length: 372
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_010380 (1119248..1119619) NCBI
- BioCyc: SPH_RS13570 BioCyc
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_1009 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361ATGTCTCAAGTAAAAGGCTTGTGTGTTTTGGATGTAGATGGAACCTTAATCCTAGAAGAA
GTGATTGATTTTTTAGGGAGAGAGGCAGGTCATGAGGCGGAAATTTCGCAGATTACAAGT
CGGGCAATGCGAGGAGAGTTGGTCTTTGAAAGCAGTTTAAGAAAAAGAGTGTCCTTGTTG
GAAGGTCTTCCTATTTTGGTCTTTGATAACGTCTTCAACTCAATTCATCTATCGCTAAAT
GTCCCAGAGTTCATCTCTATTCTCCAAAAGAATGGCATCCTAGTTGATCTGGTGTCTGGT
GGATTTACACCAATAGTTGGAGAGATTAGCAAAATCCCTTGGTATTGCCTATTTCACTGC
CAACCAGCTTGA60
120
180
240
300
360
372
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPH_RS13570
- symbol: SPH_RS13570
- description: HAD-IB family phosphatase
- length: 123
- theoretical pI: 4.64876
- theoretical MW: 13582.8
- GRAVY: 0.437398
⊟Function[edit | edit source]
- TIGRFAM: Amino acid biosynthesis Serine family phosphoserine phosphatase SerB (TIGR00338; EC 3.1.3.3; HMM-score: 104.7)and 5 moreUnknown function Enzymes of unknown specificity HAD phosphoserine phosphatase-like hydrolase, family IB (TIGR01488; HMM-score: 53.3)phosphoserine phosphatase-like hydrolase, archaeal (TIGR01491; HMM-score: 17.6)HAD phosphatase, family IIIC (TIGR01681; HMM-score: 13.4)Central intermediary metabolism Other 2,3-diketo-5-methylthio-1-phosphopentane phosphatase (TIGR01489; HMM-score: 12.7)phosphoglycolate phosphatase, TA0175-type (TIGR01487; EC 3.1.3.18; HMM-score: 12.5)
- TheSEED:
- PFAM: HAD (CL0137) HAD; haloacid dehalogenase-like hydrolase (PF12710; HMM-score: 29)and 1 moreHydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 12.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001377
- TAT(Tat/SPI): 0.000088
- LIPO(Sec/SPII): 0.000158
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_001811698 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MSQVKGLCVLDVDGTLILEEVIDFLGREAGHEAEISQITSRAMRGELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVDLVSGGFTPIVGEISKIPWYCLFHCQPA
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: glgB > SPH_RS05890 > glgD > glgA > SPH_RS13570 > SPH_RS13575 > SPH_RS05915
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1009 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.