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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae JJA
- locus tag: SPJ_0678 [new locus tag: SPJ_RS03390 ]
- pan locus tag?: PNEUPAN001677000
- symbol: SPJ_0678
- pan gene symbol?: mta
- synonym:
- product: regulator of the multidrug efflux pump PmrA
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPJ_0678 [new locus tag: SPJ_RS03390 ]
- symbol: SPJ_0678
- product: regulator of the multidrug efflux pump PmrA
- replicon: chromosome
- strand: +
- coordinates: 656641..657147
- length: 507
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP000919 (656641..657147) NCBI
- BioCyc: see SPJ_RS03390
- MicrobesOnline: 7478947 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0643 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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121
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241
301
361
421
481TTGGACTATCTAACTCGCGAAAGGCAACATCTGGATACCTTGATTTCCACCTTGCAAAAA
ACTATTCAAGAACAAAAAGGAGAAAGAAAAATGACCATTGAGGAAAAATTCACGGGATTT
AGCTATCAAGACAATCAAAAATACCACCAAGAAGCGGTAGAGAAATATGGTCAAGAAGTC
ATGGGACAAGCGCTCGAACGCCAAAAAGGTCACGAAGACGAGGCTACGGCCGCCTTTAAC
CAAGTCTTTCAAACTTTGGCACAAAATCTTCAAGTTGGTTTACCTGCAACAGCAACCGAA
AACCAGGAGCAAGCAGCCAAGCTCTTGCAAGCCATTCGCACTTATGGATTTGACTGCTCT
ATTGAGGTATTCGGTCATATCGGTAAAGGTTACGTCTACAACCCAGAGTTTAAGGAAAAC
ATTGACAAGTTTGGTTCTGAAACAGCCCAGTACACGTCAGATGCCATTGCGGCTTACGTT
CAGACAAATGCAGAAAAAATAGGCTAG60
120
180
240
300
360
420
480
507
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPJ_0678 [new locus tag: SPJ_RS03390 ]
- symbol: SPJ_0678
- description: regulator of the multidrug efflux pump PmrA
- length: 168
- theoretical pI: 4.76902
- theoretical MW: 19102
- GRAVY: -0.754762
⊟Function[edit | edit source]
- TIGRFAM: 4-nitrotryptophan synthase (TIGR04458; EC 1.-.-.-; HMM-score: 12.9)
- TheSEED :
- Regulator of the multidrug efflux pump pmrA
- PFAM: no clan defined TipAS; TipAS antibiotic-recognition domain (PF07739; HMM-score: 75.7)and 4 more4H_Cytokine (CL0053) IL5; Interleukin 5 (PF02025; HMM-score: 13.5)TPR (CL0020) MIF4G_like_2; MIF4G like (PF09090; HMM-score: 12.7)no clan defined STAT_int; STAT protein, protein interaction domain (PF02865; HMM-score: 12.3)DRIM; Down-regulated in metastasis (PF07539; HMM-score: 11.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.7721
- Cytoplasmic Membrane Score: 0.0277
- Cell wall & surface Score: 0.0121
- Extracellular Score: 0.1881
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.00496
- TAT(Tat/SPI): 0.001179
- LIPO(Sec/SPII): 0.001667
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MDYLTRERQHLDTLISTLQKTIQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAFNQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEFKENIDKFGSETAQYTSDAIAAYVQTNAEKIG
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0643 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]