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Hu17
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INV200
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JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
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R6
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serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_1757 [new locus tag: SPJ_RS08740 ]
  • pan locus tag?: PNEUPAN003346000
  • symbol: galT2
  • pan gene symbol?: galT-2
  • synonym:
  • product: galactose-1-phosphate uridylyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_1757 [new locus tag: SPJ_RS08740 ]
  • symbol: galT2
  • product: galactose-1-phosphate uridylyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1678422..1679903
  • length: 1482
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    GTGACCTTAGTAGATAAATTTGTAACACATGTCATTTCTGAAAGTTCATTTGAGGAAATG
    GATCGAATCTACCTGACCAATCGTGTTTTGGCACGAGTGGGAGAAGGTGTTTTGAAAGTT
    GAGACCAATATGGATAAATTGATTGACCTCAAGGACCAGCTAGTTGAGGAAGCCGTTCGA
    TTAGAGACGATTGAGGATAGTCAGACTGCGCGTGAAATCCTTGGTACTGAACTGATGGAC
    TTGGTGACTCCTTGTCCGAGTCAGGTCAATCGTGACTTCTGGGAAGCCTATGCCTACTCT
    CCTGAGCAAGCGATAGAGGATTTTTATCAACTCAGTCAGAAAAATGACTACATCAAACTC
    AAGGCCATTGCTAAAAATATCGCTTATCGTGTTCCATCTGATTATGGAGAACTTGAAATT
    ACCATCAATCTCTCTAAGCCTGAAAAGGATCCGAAAGAGATTGCGGTAGCCAAGTTGGTG
    CAAGCTAGTAATTATCCTCAGTGTCAACTTTGTTTAGAGAATGAGGGTTACCATGGTCGG
    GTCAACCACCCAGCTCGCAGCAACCACCGGATTATCCGTTTTGAAATGGTTGGTCAGGAA
    TGGGGTTTCCAGTATTCGCCCTATGCTTACTTTAATGAGCATTGTATCTTTTTAGATGGC
    CAGCATCGTCCCATGGCCATTAGTCGTCAGAGTTTTGAACGTCTGTTGGCTATCGTAGAG
    CAGTTTCCAGGATATTTTGCTGGATCTAATGCCGACCTGCCGATTGTGGGGGGCTCTATT
    CTAACTCATGATCATTATCAGGGAGGCCGTCACGTATTTCCTATGGAATTGGCTCCCTTG
    CAAAAGACCTTCCGATTTGCTGGTTTTGAGCAGGTCAAGGCTGGAATTATCAAGTGGCCA
    ATGTCTGTCCTACGCTTGACTTCGGATTCCAAAGAGGATTTGATTAACTTAGCTGATAAG
    ATTTTCCAGGAATGGCGTCAGTATTCAGATTCTAGTGTGCAGATTTTAGCAGAGACAGAC
    GGGACACCGCATCACACCATCACACCAATAGCGCGTAAGCGTGATGGACAGTTTGAGTTG
    GACTTGGTCTTGCGAGACAATCAGACTTCAGCAGAGCATCCTGATGGCATCTATCATCCC
    CACAAGGATGTCCAACATATCAAGAAGGAAAATATCGGCTTGATTGAGGTCATGGGCTTG
    GCAATCTTGCCACCACGTCTGAAAGAAGAAGTAGAGCAAGTCGCTAGCTATCTTGTAGGA
    GAAGCTGTTACAGTTGCCGATTATCATCAGGAGTGGGCAGACCAACTCAAATCCCAACAT
    CCAGACCTAACGGATAAAGAAAAAGCCCTTGCAATCGTCAAGGACTCTGTGGGTGCTATC
    TTTGTGCGTGTACTTGAGGATGCAGGAGTCTACAAGCAGACAGAACAAGGGCAGACAGCC
    TTTATGCGCTTTGTGGAACAGGTCGGAATTTTACTAGACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1482

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_1757 [new locus tag: SPJ_RS08740 ]
  • symbol: GalT2
  • description: galactose-1-phosphate uridylyltransferase
  • length: 493
  • theoretical pI: 4.98033
  • theoretical MW: 56222.3
  • GRAVY: -0.361663

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.7.10?  ExPASy
    UTP--hexose-1-phosphate uridylyltransferase UTP + alpha-D-galactose 1-phosphate = diphosphate + UDP-alpha-D-galactose
  • TIGRFAM:
    Metabolism Energy metabolism Sugars galactose-1-phosphate uridylyltransferase (TIGR01239; EC 2.7.7.12; HMM-score: 769.4)
  • TheSEED  :
    • Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
    Carbohydrates Di- and oligosaccharides Lactose and Galactose Uptake and Utilization  Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
  • PFAM:
    HIT (CL0265) GalP_UDP_transf; Galactose-1-phosphate uridyl transferase, N-terminal domain (PF01087; HMM-score: 135.3)
    GalP_UDP_tr_C; Galactose-1-phosphate uridyl transferase, C-terminal domain (PF02744; HMM-score: 131.1)
    and 2 more
    DUF4922; Domain of unknown function (DUF4922) (PF16269; HMM-score: 13.6)
    no clan defined DUF4889; Domain of unknown function (DUF4889) (PF16230; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0018
    • TAT(Tat/SPI): 0.000132
    • LIPO(Sec/SPII): 0.000238
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLKVETNMDKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPEQAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLVQASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFLDGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPMELAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENIGLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKALAIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: GalR* (repression) regulon, CcpA regulon
    GalR*(TF)important in Galactose utilization; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 
    CcpA(TF)important in Global catabolite repression; RegPrecise    transcription unit transferred from TIGR4 data RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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