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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPNA45
  • locus tag: SPNA45_RS02370 [old locus tag: SPNA45_00399 ]
  • pan locus tag?: PNEUPAN003346000
  • symbol: SPNA45_RS02370
  • pan gene symbol?: galT-2
  • synonym:
  • product: UDP-glucose--hexose-1-phosphate uridylyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNA45_RS02370 [old locus tag: SPNA45_00399 ]
  • symbol: SPNA45_RS02370
  • product: UDP-glucose--hexose-1-phosphate uridylyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 400374..401855
  • length: 1482
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018594 (400374..401855) NCBI
  • BioCyc: SPNA45_RS02370 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1633 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    GTGACCTTAGTAGATAAATTTGTAACACATGTCATTTCTGAAAGTTCATTTGAGGAAATG
    GATCGAATCTACCTGACCAATCGTGTTTTGGCACGAGTGGGAGAAGGTGTTTTGGAAGTT
    GAGACCAATCTGGATAAATTGATTGACCTCAAGGACCAGCTAGTTGAGGAAGCCGTTCGA
    TTAGAGACGATTGAGGATAGTCAGACTGCGCGTGAAATCCTTGGTACTGAATTGATGGAC
    TTGGTGACTCCTTGTCCGAGTCAGGTCAATCGTGACTTCTGGGAAGCCTATGCCTACTCT
    CCTGAGCAAGCGATAGAGGATTTTTATCAACTCAGTCAGAAAAATGACTACATCAAACTC
    AAGGCCATTGCTAAAAATATCGCTTATCGTGTTCCATCTGATTATGGAGAACTTGAAATT
    ACCATCAATCTCTCTAAGCCTGAAAAGGATCCGAAAGAGATTGCGGCAGCCAAGTTGGTG
    CAAGCTAGTAATTATCCTCAGTGTCAACTTTGTTTAGAGAATGAGGGTTACCATGGTCGG
    GTCAACCACCCAGCTCGCACCAACCACCGGATTATCCGTTTTGAAATGGTTGGTCAGGAA
    TGGGGTTTCCAGTATTCGCCCTATGCTTACTTTAATGAGCATTGTATCTTTTTAGATGGC
    CAGCATCGTCCCATGGCCATTAGTCGTCAGAGTTTTGAACGTCTGTTGGCTATCGTAGAG
    CAGTTTCCAGGATATTTTGCTGGATCTAATGCCGACCTGCCGATTGTGGGGGGCTCTATT
    CTAACTCATGATCATTATCAGGGAGGCCGTCACGTATTTCCTATGGAATTGGCTCCCTTG
    CAAAAGACCTTCCGATTTGCTGGTTTTGAGCAGGTCAAGGCTGGAATTATCAAGTGGCCA
    ATGTCTGTCCTACGCTTGACTTCGGATTCCAAAGAGGATTTGATTAACTTAGCTGATAAG
    ATTTTCCAGGAATGGCGTCAGTATTCAGATTCTAGTGTGCAGATTTTAGCAGAGACAGAC
    GGGACACCGCATCACACCATCACACCAATAGCGCGTAAGCGTGATGGACAGTTTGAGATG
    GACTTGGTCTTGCGAGACAATCAGACTTCAGCAGAGCATCCTGATGGCATCTATCATCCC
    CACAAGGATGTCCAACATATCAAGAAGGAAAATATCGGCTTGATTGAGGTCATGGGCTTG
    GCAATCTTGCCACCACGTCTGAAAGAAGAAGTGGAGCAAGTCGCTAGCTATCTTGTAGGA
    GAAGCTGTTACAGTTGCCGATTATCATCAGGAGTGGGCAGACCAACTCAAATCCCAACAT
    CCAGACCTAACGGATAAAGAAAAAGCCCTTGCAATCGTCAAGGACTCTGTGGGTGCTATC
    TTTGTGCGTGTACTTGAGGATGCAGGAGTCTACAAGCAGACAGAACAAGGGCAGACAGCC
    TTTATGCGCTTTGTGGAACAGGTCGGAATTTTACTAGACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1482

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNA45_RS02370 [old locus tag: SPNA45_00399 ]
  • symbol: SPNA45_RS02370
  • description: UDP-glucose--hexose-1-phosphate uridylyltransferase
  • length: 493
  • theoretical pI: 4.87728
  • theoretical MW: 56209.3
  • GRAVY: -0.365517

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.7.12?  ExPASy
    UDP-glucose--hexose-1-phosphate uridylyltransferase UDP-alpha-D-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
  • TIGRFAM:
    Metabolism Energy metabolism Sugars galactose-1-phosphate uridylyltransferase (TIGR01239; EC 2.7.7.12; HMM-score: 769.2)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    HIT (CL0265) GalP_UDP_transf; Galactose-1-phosphate uridyl transferase, N-terminal domain (PF01087; HMM-score: 137.2)
    GalP_UDP_tr_C; Galactose-1-phosphate uridyl transferase, C-terminal domain (PF02744; HMM-score: 131.2)
    and 1 more
    DUF4922; Domain of unknown function (DUF4922) (PF16269; HMM-score: 13.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001756
    • TAT(Tat/SPI): 0.000125
    • LIPO(Sec/SPII): 0.000208
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000176991 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNLDKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPEQAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLVQASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFLDGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPMELAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQILAETDGTPHHTITPIARKRDGQFEMDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENIGLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKALAIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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