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serotype 4
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670-6B
serotype 6B
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serotype 6A
70585
serotype 5
A026
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A66
serotype 3
AP200
serotype 11A
ASP0581
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ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1852 [new locus tag: SP_RS09190 ]
  • pan locus tag?: PNEUPAN003346000
  • symbol: galT-2
  • pan gene symbol?: galT-2
  • synonym:
  • product: galactose-1-phosphate uridylyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1852 [new locus tag: SP_RS09190 ]
  • symbol: galT-2
  • product: galactose-1-phosphate uridylyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1759048..1760529
  • length: 1482
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    GTGACCTTAGTAAATAAATTTGTAACACATGTCATTTCTGAAAGCTCATTTGAGGAAATG
    GATCGAATCTATCTGACCAATCGTGTTTTGGCACGAGTGGGAGAAGGTGTTTTGGAAGTT
    GAGACCAATCTGGATAAATTGATTGACCTCAAGGACCAGCTGGTTGAAGAAGCCGTTCGA
    TTAGAGACGATTGAGGATAGTCAGACTGCGCGTGAAATCCTTGGTGCTGAACTGATGGAT
    TTGGTGACTCCTTGTCCAAGTCAGGTCAATCGTGATTTTTGGGCAACCTACGCCCACTCT
    CCAGAACAAGCGATAGAGGATTTTTACCAACTCAGTCAGAAAAATGACTACATCAAACTC
    AAGGCCATTGCTAGAAATATCGCTTATCGTGTTCCATCTGACTACGGAGAACTTGAAATT
    ACCATCAATCTCTCTAAGCCTGAAAAAGATCCCAAAGAGATTGTGGCAGCCAAGTTGGTG
    CAAGCTAGTAATTATCCTCAGTGTCAGCTTTGTCTAGAGAATGAGGGCTACCATGGTCGA
    GTTAACCACCCAGCTCGTAGCAATCACCGTATTATCCGTTTTGAAATGGTTGGTCAGGAA
    TGGGGTTTCCAGTATTCGCCCTATGCTTACTTTAATGAGCATTGTATCTTTTTAGATGGC
    CAGCATCGTCCCATGGCCATTAGTCGTCAGAGTTTTGAACGTCTGTTGGCTATCGTAGAC
    CAGTTTCCAGGATATTTTGCTGGATCTAATGCCGACCTGCCGATTGTGGGGGGCTCTATT
    CTAACTCATGATCATTATCAGGGAGGCCGTCACGTATTTCCTATGGAATTGGCTCCCTTG
    CAAAAGGCCTTCCGATTTGCTGGTTTTGAGCAGGTCAAGGCTGGAATTGTCAAGTGGCCC
    ATGTCTGTCCTACGTTTGACTTCGGATTCCAAAGAGGATTTGATCAATTTGGCTGATAAG
    ATTTTGCAGGAATGGCGCCAGTATTCAGATCCTGCAGTGCAGATTTTGGCAGAGACAGAC
    AGGACACCGCATCACACTATCACACCCATTGCCCGCAAACGCGATGGACAGTTTGAGTTG
    GACTTGGTCTTGCGAGACAATCAGACTTCAGCAGAGTATCCTGATGGTATCTATCATCCC
    CACAAGGATGTCCAACATATCAAGAAGGAAAATATCGGCTTGATTGAGGTCATGGGCTTG
    GCAATCTTGCCACCACGTCTGAAAGAAGAAGTGGAGCAAGTCGCTAGCTATCTTGTAGGA
    GAAGCTGTTACAGTTGCCGATTATCATCAGGAGTGGGCAGACCAACTCAAATCCCAACAT
    CCAGACCTAACGGATAAAGAAAAAGCCCTTGCAATCGTCAAGGACTCTGTGGGTGCTATC
    TTTGCGCGTGTACTTGAGGATGCAGGAGTCTACAAGCAGACAGAACAAGGGCAGACAGCC
    TTTATGCGCTTTGTGGAACAGGTCGGAATTTTACTAGACTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1482

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1852 [new locus tag: SP_RS09190 ]
  • symbol: GalT-2
  • description: galactose-1-phosphate uridylyltransferase
  • length: 493
  • theoretical pI: 5.03666
  • theoretical MW: 56147.3
  • GRAVY: -0.350507

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.7.10?  ExPASy
    UTP--hexose-1-phosphate uridylyltransferase UTP + alpha-D-galactose 1-phosphate = diphosphate + UDP-alpha-D-galactose
  • TIGRFAM:
    Metabolism Energy metabolism Sugars galactose-1-phosphate uridylyltransferase (TIGR01239; EC 2.7.7.12; HMM-score: 768.5)
  • TheSEED  :
    • Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
    Carbohydrates Di- and oligosaccharides Lactose and Galactose Uptake and Utilization  Galactose-1-phosphate uridylyltransferase (EC 2.7.7.10)
  • PFAM:
    HIT (CL0265) GalP_UDP_transf; Galactose-1-phosphate uridyl transferase, N-terminal domain (PF01087; HMM-score: 135.3)
    GalP_UDP_tr_C; Galactose-1-phosphate uridyl transferase, C-terminal domain (PF02744; HMM-score: 132.6)
    and 1 more
    DUF4922; Domain of unknown function (DUF4922) (PF16269; HMM-score: 13.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00199
    • TAT(Tat/SPI): 0.000117
    • LIPO(Sec/SPII): 0.000209
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTLVNKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNLDKLIDLKDQLVEEAVRLETIEDSQTAREILGAELMDLVTPCPSQVNRDFWATYAHSPEQAIEDFYQLSQKNDYIKLKAIARNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLVQASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFLDGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPMELAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENIGLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKALAIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEQVGILLD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulators: CcpA regulon, GalR (repression) regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 
    GalR(TF)important in Galactose utilization; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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