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serotype 19A
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JJA
serotype 14
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serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
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SPN032672
serotype 1
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serotype 3
SPN034183
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SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_2041 [new locus tag: SPJ_RS10130 ]
  • pan locus tag?: PNEUPAN003622000
  • symbol: SPJ_2041
  • pan gene symbol?: ulaD
  • synonym:
  • product: orotidine 5'-phosphate decarboxylase / humps family, putative

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_2041 [new locus tag: SPJ_RS10130 ]
  • symbol: SPJ_2041
  • product: orotidine 5'-phosphate decarboxylase / humps family, putative
  • replicon: chromosome
  • strand: -
  • coordinates: 1903259..1903924
  • length: 666
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACAAAAAGAATACCTAATTTACAAGTTGCATTAGACCATTCAGACTTGCAAGGAGCG
    ATTAAAGCAGCTGTTTCTGTTGGTCAGGAAGTAGATATTATCGAAGCTGGAACTGTTTGC
    TTGCTTCAAGTTGGAAGTGAACTGGCTGAAGTCTTGCGTAGCCTTTTCCCAGATAAGATT
    ATTGTGGCAGACACAAAATGTGCTGATGCTGGTGGAACAGTTGCTAAAAATAATGCGGTT
    CGTGGAGCAGACTGGATGACTTGTATCTGTTGTGCAACCATCCCTACTATGGAAGCAGCT
    CTAAAGGCTATCAAGACTGAACGAGGAGAACGAGGCGAAATCCAGATCGAGCTTTATGGC
    GATTGGACTTTTGAACAAGCTCAGCTTTGGCTAGATGCAGGTATCTCACAAGCTATTTAT
    CACCAATCTCGTGATGCTCTTCTTGCTGGTGAAACTTGGGGTGAAAAAGACCTTAATAAG
    GTTAAAAAACTCATTGACATGGGCTTCCGTGTATCTGTAACAGGTGGTCTAGATGTAGAT
    ACTCTCAAACTCTTTGAAGGTGTTGATATCTTTACCTTTATCGCAGGTCGTGGAATTACA
    GAGGCTGCGGATCCAGCAGGAGCAGCGCGTGCCTTCAAGGATGAAATCAAACGAATTTGG
    GGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    666

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_2041 [new locus tag: SPJ_RS10130 ]
  • symbol: SPJ_2041
  • description: orotidine 5'-phosphate decarboxylase / humps family, putative
  • length: 221
  • theoretical pI: 4.64266
  • theoretical MW: 23868.2
  • GRAVY: 0.0452489

⊟Function[edit | edit source]

  • reaction:
    EC 4.1.1.23?  ExPASy
    Orotidine-5'-phosphate decarboxylase Orotidine 5'-phosphate = UMP + CO2
  • TIGRFAM:
    3-hexulose-6-phosphate synthase (TIGR03128; EC 4.1.2.43; HMM-score: 103.6)
    and 3 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotidine 5'-phosphate decarboxylase (TIGR01740; EC 4.1.1.23; HMM-score: 36.6)
    Metabolism Energy metabolism Electron transport NADH-quinone oxidoreductase, B subunit (TIGR01957; HMM-score: 12.9)
    conserverd hypothetical protein (TIGR02448; HMM-score: 12.1)
  • TheSEED  :
    • 3-keto-L-gulonate 6-phosphate decarboxylase
    Carbohydrates Monosaccharides L-ascorbate utilization (and related gene clusters)  3-keto-L-gulonate 6-phosphate decarboxylase
  • PFAM:
    TIM_barrel (CL0036) OMPdecase; Orotidine 5'-phosphate decarboxylase / HUMPS family (PF00215; HMM-score: 94.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005219
    • TAT(Tat/SPI): 0.00057
    • LIPO(Sec/SPII): 0.000349
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQVGSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALKAIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKVKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKRIWG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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