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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 20-APR-2021
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae JJA
- locus tag: SPJ_RS04480 [old locus tag: SPJ_0895 ]
- pan locus tag?: PNEUPAN001971000
- symbol: SPJ_RS04480
- pan gene symbol?: comEA
- synonym: celA
- product: helix-hairpin-helix domain-containing protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPJ_RS04480 [old locus tag: SPJ_0895 ]
- symbol: SPJ_RS04480
- product: helix-hairpin-helix domain-containing protein
- replicon: chromosome
- strand: +
- coordinates: 856567..857217
- length: 651
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012466 (856567..857217) NCBI
- BioCyc: SPJ_RS04480 BioCyc
- MicrobesOnline: see SPJ_0895
- PneumoBrowse for strain D39V: SPV_0843 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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601ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTG
GGCTTGCTTGTAGGCGGATTTTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAA
ACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATTTGGTATCCGAAAAGGAAGTG
AACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTT
CAGAAGGCTGGTGGCTTGACAGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAA
GTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAGAAGAAGCAGTTAGTCAACAG
ACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATT
GACCATCGTGAGGCAAATGGCAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGC
ATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTACAGTGGATTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPJ_RS04480 [old locus tag: SPJ_0895 ]
- symbol: SPJ_RS04480
- description: helix-hairpin-helix domain-containing protein
- length: 216
- theoretical pI: 5.52067
- theoretical MW: 23191.3
- GRAVY: -0.387963
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes DNA transformation comEA protein (TIGR01259; HMM-score: 184)and 7 moreCellular processes DNA transformation competence protein ComEA helix-hairpin-helix repeat region (TIGR00426; HMM-score: 71.9)DNA metabolism DNA replication, recombination, and repair DNA polymerase III, alpha subunit, Gram-positive type (TIGR01405; EC 2.7.7.7; HMM-score: 19.1)Unknown function Enzymes of unknown specificity putative DNA modification/repair radical SAM protein (TIGR03916; HMM-score: 14.4)DNA metabolism DNA replication, recombination, and repair Holliday junction DNA helicase RuvA (TIGR00084; EC 3.6.4.12; HMM-score: 13.9)DNA metabolism DNA replication, recombination, and repair DNA polymerase III, alpha subunit (TIGR00594; EC 2.7.7.7; HMM-score: 13.7)polysaccharide export protein EpsE (TIGR03028; HMM-score: 13.2)class III signal peptide protein, archaeosortase D/PIP-CTERM system (TIGR04205; HMM-score: 11.5)
- TheSEED: see SPJ_0895
- PFAM: HHH (CL0198) HHH_3; Helix-hairpin-helix motif (PF12836; HMM-score: 84.6)and 11 moreUbiquitin (CL0072) SLBB; SLBB domain (PF10531; HMM-score: 53.7)HHH (CL0198) HHH; Helix-hairpin-helix motif (PF00633; HMM-score: 47.2)HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 26.7)HHH_6; Helix-hairpin-helix motif (PF14579; HMM-score: 24.5)HHH_2; Helix-hairpin-helix motif (PF12826; HMM-score: 23.7)T2SSK; Type II secretion system (T2SS), protein K (PF03934; HMM-score: 19.5)PsbU; Photosystem II 12 kDa extrinsic protein (PsbU) (PF06514; HMM-score: 17.9)HHH_8; Helix-hairpin-helix domain (PF14716; HMM-score: 16.5)RNA_pol_A_CTD; Bacterial RNA polymerase, alpha chain C terminal domain (PF03118; HMM-score: 15.4)IMS_HHH; IMS family HHH motif (PF11798; HMM-score: 14.1)no clan defined UPF0758_N; UPF0758 N-terminal (PF20582; HMM-score: 12.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.17
- Cytoplasmic Membrane Score: 9.51
- Cellwall Score: 0.16
- Extracellular Score: 0.15
- Internal Helix: 1
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.226741
- TAT(Tat/SPI): 0.018476
- LIPO(Sec/SPII): 0.025673
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKASLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0843 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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