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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 05-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_RS07670 [old locus tag: SPJ_1548 ]
  • pan locus tag?: PNEUPAN003067000
  • symbol: SPJ_RS07670
  • pan gene symbol?: —
  • synonym:
  • product: ABC transporter permease

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_RS07670 [old locus tag: SPJ_1548 ]
  • symbol: SPJ_RS07670
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 1465744..1468452
  • length: 2709
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012466 (1465744..1468452) NCBI
  • BioCyc: SPJ_RS07670 BioCyc
  • MicrobesOnline: see SPJ_1548
  • PneumoBrowse for strain D39V: SPV_1465 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    ATGATCAAGCGAAAAACCTATTGGAAGGACTTAATTCAGTCCTTTACAGGCTCCAAGGGA
    CGTTTTTTATCTATCTTGACCTTGATGATGTTGGGCTCTCTAGCCCTAGTAGGTCTCAAA
    GTAACCAGTCCCAACATGGAGGCGACAGCTAATGCTTATTTAACAACTGCTCAAACCTTG
    GATTTGGCAGTTATGTCTAATTATGGTTTGGATCAAACAGACCAAGAAGAACTAGAACAG
    ATAGAGGGCGCAGAGGTTGAGTTTGGCTATTTGACAGATGTGACTATGGAAAATGGGCAG
    AATGCGATTCGGCTGTACTCCAAACCAGAGCGAATTTCAACCTTTCAGCTAAGAGAGGGA
    CGACTTCCTCAGTCAGACCAGGAAATCGCTTTGGTAAGTCATCTGCAGAGTCAATATAGC
    GTGGGACAGGAGATTAGTTTTAAAGAAAAAGAAGAGGGTCATTCCTCTTTAAAAGACCAT
    ACTTATACCATTACTGGTTTTGTGGATTCGGCTGAAATCCTCTCCCAGCGAGATATGGGC
    TACGCAGCAAGTGGAAGTGGGACTCTGACAGCCTACGGGGTCATTTTACCTAGTCAGTTT
    GATCAGAAAGTCTACAATATAGCTCGTTTGAAATATCAAGATTTGTCAGGTTTAAATGCC
    TTTTCATCAGCTTATGAAGAAAAATCCAAGCAACATCAGGAAGACCTTGAACAAGCTTTG
    TCAGATAATGGCAAGGCACGTCTGCAAGTCTTGAAAAAAGAAGGACAAGAGTCTCTAGAC
    AAGGGCCAAGAAACCCTTGATAAGGCTCAGGCAAATTTGCAGGAAGGCAAGCGTCGTTTA
    GCAGCTGCTCAAGTTCGTATACAGGCTCAAGAAAGTCAACTAGCCTTGCTTCCTCAAGCT
    CAGAGAGAGCAGGCCCATGCTCAACTTACTCAAGCCAAGCAGGAATTGAGCAAGGAAGAG
    GACAAACTAAAGCAGGCTGAACAAAATCTAGCCCAAGAAAAGGAAAAATTAGAAAAACAT
    CAGCAAATCTTGGATGATTTAGCTGAGCCCAAGTATCAAGTCTATAATCGTCAGACCATG
    CCTGGTGGTCAGGGCTATCTCATGTATAGCAATGCTACAGCCAGTATTCGGGCAGTGGGC
    AATATCTTTCCTGTAGTGCTTTATGCTGTTGCAGCCATGGTGACCTTTACAACCATGACT
    CGCTTTGTGGATGAAGAGCGAACTCATGCAGGGATTTTTAAGGCCTTGGGCTATCGCAGT
    GAGGATATTATCGCCAAATTTCTCCTCTACGGTCTAGTAGCTGGGACTGTAGGAACAGCT
    CTAGGTAGCATACTTGGCCATTATTTACTAGCCAGTGTAATTTCAAGTGTCATTACAAAA
    GGCATGGTGGTGGGAGAAACCCAGATTCAGTTCTATTGGACCTATAGTTTATTAGCTCTT
    GGTTTGAGTTGGTTGGCGAGTGTGTTACCAGCCTATCTGGTGGCTCGTAGGGAACTACAT
    GACGAAGCAGCCCAGCTTTTATTGCCTAAACCTCCTGTTAAAGGAGCTAAAATCTTACTG
    GAACGCATCGGTTTTATCTGGCGCCGTCTCAGTTTTACCCATAAGGTAACAGCCCGCAAT
    ATCTTCCGTTATAAGCAACGGATGTTGATGACGATCTTTGGTGTGGCAGGTTCTGTAGCC
    CTGCTCTTTGCAGGTTTGGGAATCCAATCCTCTGTAGCAGGAGTTCCGTCTAAACAGTTT
    CAACAAATCCAACAGTATCAGATGATTGTTTCTGAAAATCCTAGTGCGACCAATCAGGAC
    AAGAAAGAGCTAGAAGGAGTGTTGAAAGGGCAGGAGATACAAGCCTACCAGAAAATTTAT
    TCTAAAACGCTAGACAAGGATTTCAAAGGCAAGGCTGGTCTTCAGACCATTACCCTTATG
    ATGACAGAGAAGGAGGATTTGACGCCCTTTATTCATCTGCAACATCATCAGCAAGAGTTG
    ACATTAAAAGCTGGGGTCGTTATCACGGATAAACTCTCCCAGCTGGCAGGTGTCAAGGTT
    GGGCAGACTTTAGAAATTGAAGGTAAGGAGCTAAAGGTCGCTGCCATTGCTGAGAACTAC
    GTTGGTCATTTTATTTATATGAGTCAGGCTAGCTATGAGCAAATTTACGGACAGCTACCC
    CAAGCCAACACTTATTTGGTCTCGTTAAGGGATACCAGTGCTACTAGTATCGAAAGGCAG
    GCAGGCTTGCTTATGAATCAATCTGCGGTGTCCAGCGTTGTCCAGAATGCTTCAGCCATC
    CGACTCTTTGACTCGGTCGCTAGCTCACTCAATCAGACCATGACCATCTTGGTCATCGTA
    TCGGTTCTGTTGGCTATCGTTATCCTCTACAATTTGACCAATATCAACGTAGCTGAGAGA
    ATCCGTGAGCTCTCCACTATCAAGGTTCTCGGTTTTCATAATAATGAAGTCACTCTCTAC
    ATTTACCGTGAGACGATTGTGCTGTCCCTTGTGGGAATCGTACTTGGTTTGGTATCTGGT
    TTCTATTTACATCAATTTTTGATTCAAATGATTTCGCCTGCGACTATTCTCTTTTATCCG
    CAGGTAGGCTGGGAAGTCTATGTGATTCCAGTGGCAGCAGTAAGCATCATTTTGACCTTG
    CTTGGTTTCTTTGTCAATTATCATCTGAGAAAGGTTGATATGCTTGAAGCACTGAAATCT
    GTAGAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2709

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_RS07670 [old locus tag: SPJ_1548 ]
  • symbol: SPJ_RS07670
  • description: ABC transporter permease
  • length: 902
  • theoretical pI: 7.01614
  • theoretical MW: 100425
  • GRAVY: -0.0535477

⊟Function[edit | edit source]

  • TIGRFAM:
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 32.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 27.1)
    and 6 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein LolE (TIGR02213; HMM-score: 25.3)
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 14.9)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 14.9)
    mobilome CxxCx(11)CxxC protein (TIGR04402; HMM-score: 14.1)
    Metabolism Transport and binding proteins Other ABC exporter transmembrane subunit, DevC protein (TIGR01185; HMM-score: 9.8)
    SEC10/PgrA surface exclusion domain (TIGR04320; HMM-score: 9.2)
  • TheSEED: see SPJ_1548
  • PFAM:
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 104.1)
    and 6 more
    no clan defined MacB_PCD; MacB-like periplasmic core domain (PF12704; HMM-score: 28.5)
    RsgI_N; Anti-sigma factor N-terminus (PF12791; HMM-score: 16.1)
    Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 11.8)
    Vir (CL0411) Plasmodium_Vir; Plasmodium vivax Vir protein (PF05795; HMM-score: 11.8)
    no clan defined ODV-E18; Occlusion-derived virus envelope protein ODV-E18 (PF10717; HMM-score: 9.9)
    DUF4017; Protein of unknown function (DUF4017) (PF13209; HMM-score: 8.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9996
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0003
  • SignalP: Signal peptide SP(Sec/SPI) length 50 aa
    • SP(Sec/SPI): 0.529695
    • TAT(Tat/SPI): 0.028058
    • LIPO(Sec/SPII): 0.052632
    • Cleavage Site: CS pos: 50-51. ATA-NA. Pr: 0.1375
  • predicted transmembrane helices (TMHMM): 8

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MIKRKTYWKDLIQSFTGSKGRFLSILTLMMLGSLALVGLKVTSPNMEATANAYLTTAQTLDLAVMSNYGLDQTDQEELEQIEGAEVEFGYLTDVTMENGQNAIRLYSKPERISTFQLREGRLPQSDQEIALVSHLQSQYSVGQEISFKEKEEGHSSLKDHTYTITGFVDSAEILSQRDMGYAASGSGTLTAYGVILPSQFDQKVYNIARLKYQDLSGLNAFSSAYEEKSKQHQEDLEQALSDNGKARLQVLKKEGQESLDKGQETLDKAQANLQEGKRRLAAAQVRIQAQESQLALLPQAQREQAHAQLTQAKQELSKEEDKLKQAEQNLAQEKEKLEKHQQILDDLAEPKYQVYNRQTMPGGQGYLMYSNATASIRAVGNIFPVVLYAVAAMVTFTTMTRFVDEERTHAGIFKALGYRSEDIIAKFLLYGLVAGTVGTALGSILGHYLLASVISSVITKGMVVGETQIQFYWTYSLLALGLSWLASVLPAYLVARRELHDEAAQLLLPKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGLGIQSSVAGVPSKQFQQIQQYQMIVSENPSATNQDKKELEGVLKGQEIQAYQKIYSKTLDKDFKGKAGLQTITLMMTEKEDLTPFIHLQHHQQELTLKAGVVITDKLSQLAGVKVGQTLEIEGKELKVAAIAENYVGHFIYMSQASYEQIYGQLPQANTYLVSLRDTSATSIERQAGLLMNQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVAERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVSGFYLHQFLIQMISPATILFYPQVGWEVYVIPVAAVSIILTLLGFFVNYHLRKVDMLEALKSVE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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