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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 20-APR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_RS07895 [old locus tag: SPJ_1590 ]
  • pan locus tag?: PNEUPAN003099000
  • symbol: recG
  • pan gene symbol?: recG
  • synonym:
  • product: ATP-dependent DNA helicase RecG

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_RS07895 [old locus tag: SPJ_1590 ]
  • symbol: recG
  • product: ATP-dependent DNA helicase RecG
  • replicon: chromosome
  • strand: -
  • coordinates: 1514260..1516275
  • length: 2016
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_012466 (1514260..1516275) NCBI
  • BioCyc: SPJ_RS07895 BioCyc
  • MicrobesOnline: see SPJ_1590
  • PneumoBrowse for strain D39V: SPV_1507 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    ATGAATCTACATCAACCCTTGCATGTCTTGCCTGGTGTGGGACCAAAGTCAGCAGAAAAA
    TACGCCAAACTAGGAATTGAAAACTTGCAAGATCTCTTGCTCTACTTTCCTTTCCGTTAT
    GAAGACTTCAAAACCAAGCAGGTGCTGGAGCTGGAAGACGGTGAGAAGGCAGTTCTTTCT
    GGTCAGGTAGTGACTCCTGCTAGTGTCCAGTATTATGGTTTCAAGCGCAATCGCCTGCGT
    TTTAGTCTCAAGCAGGGAGAGGTCGTTTTTGCGGTGAATTTCTTTAACCAGCCCTATCTG
    GCTGATAAAATAGAGTTGGGAGCAACCCTTGCTGTCTTTGGAAAATGGGACCGCGCTAAG
    GCTAGTCTGACTGGGATGAAGGTTCTGGCTCAGGTAGAAGATGACCTCCAGCCTGTCTAT
    CGTCTGGCTCAGGGAATCAGTCAGGCCAGTCTGGTCAAGGTCATCAAGACGGCTTTTGAT
    CAGGGACTGGACCTCTTGATAGAAGAAAATCTGCCCCAGTCTTTACTAGACAAATACAAA
    CTCATGTCCCGTTGTCAGGCAGTCCGAGCTATGCATTTTCCAAAGGATTTGGCAGAATAC
    AAGCAGGCTCTTCGCCGTATAAAGTTTGAGGAACTCTTTTATTTCCAAATGCAGCTGCAG
    ATGCTCAAGTCTGAAAATAGAGTTCAGGGAAGTGGTCTGGTTCTGAATTGGTCTCAGGAA
    AAAGTGACAGCAGTTAAAGTAAGTCTTCCTTTTGCCCTGACCCAAGCTCAGGAAAAGAGT
    TTGCAGGAAATTTTAACTGATATGAAGTCCGACCACCACATGAATCGTCTCCTACAAGGG
    GATGTGGGGAGTGGAAAAACGGTAGTCGCTGGCTTGGCCATGTTTGCGGCAGTGACAGCA
    GGTTATCAGGCTGCCCTAATGGTACCAACAGAAATCCTCGCAGAGCAACACTTTGAGAGT
    TTACAGAACCTTTTTCCCAATTTGAAACTGGCTCTCTTGATAGGTTCCTTGAAAGCTGCA
    GAAAAGAGAGAGGTCTTGGAGACCATTGCCAAGGGTGAGGCTGATTTGATTATCGGAACT
    CACGCTCTGATACAAGATGGGGTGGAGTATGCTCGTCTTGCTTTGATTATTATCGATGAG
    CAGCACCGTTTTGGTGTAGGGCAAAGGCGTATTTTACGGGAAAAAGGTGACAATCCAGAT
    GTCCTCATGATGACGGCGACTCCCATTCCACGGACGCTTGCCATCACAGCCTTTGGAGAT
    ATGGATGTTTCCATTATCGACCAGATGCCAGCAGGTCGGAAGCCTATTGTGACGCGCTGG
    ATCAAACATGAGCAACTACCTCAGGTCTTGACTTGGTTAGAGGGGGAAATTCAAAAAGGT
    TCCCAAGCCTATGTCATCTCTCCTTTGATTGAAGAATCAGAAGCTCTAGATTTGAAAAAT
    GCCATTGCCTTATCAGAGGAGTTGACGACTCATTTTGCAGGCAAGGCAGAGGTGGCTCTT
    CTACATGGTAGGATGAAGAGTGACGAAAAAGACCAGATCATGCAGGATTTCAAGGAGAGA
    AAGACGGATATTCTGGTTTCGACGACGGTTATTGAGGTTGGGGTCAACGTTCCCAATGCG
    ACTGTCATGATTATCATGGATGCCGATCGCTTCGGTCTCAGTCAACTTCACCAGCTTAGA
    GGTCGTGTCGGTCGGGGGGACAAGCAGTCCTACGCTGTTCTCGTTGCTAATCCCAAGACG
    GATTCTGGGAAAGACCGCATGCGTATCATGACAGAAACGACCAATGGATTTGTCCTTGCG
    GAGGAAGATTTGAAAATGCGTGGTTCTGGTGAGATTTTTGGAACCAGACAGTCAGGACTT
    CCAGAGTTCCAAGTGGCTGATATTATCGAAGATTTTCCGATTTTAGAAGAAGCAAGAAAG
    GTTGCTAGCTACATTAGTTCTATAGAAGCTTGGCAAGAAGATCCAGAGTGGCGCATGATT
    GCCCTTCATCTGGAAAAGAAAGAACATCTGGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2016

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_RS07895 [old locus tag: SPJ_1590 ]
  • symbol: RecG
  • description: ATP-dependent DNA helicase RecG
  • length: 671
  • theoretical pI: 6.07148
  • theoretical MW: 75330.5
  • GRAVY: -0.166766

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.4.12?  ExPASy
    DNA helicase ATP + H2O = ADP + phosphate
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecG (TIGR00643; EC 3.6.4.12; HMM-score: 847.4)
    and 12 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair transcription-repair coupling factor (TIGR00580; EC 3.6.1.-; HMM-score: 371.5)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair primosomal protein N' (TIGR00595; EC 3.6.1.-; HMM-score: 63.7)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit B (TIGR00631; EC 3.1.25.-; HMM-score: 44.5)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair reverse gyrase (TIGR01054; EC 3.6.4.12,5.99.1.3; HMM-score: 38)
    CRISPR-associated helicase Cas3 (TIGR01587; HMM-score: 37.5)
    DEXH box helicase, DNA ligase-associated (TIGR04121; EC 3.6.4.-; HMM-score: 32.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase, RecQ family (TIGR00614; EC 3.6.4.12; HMM-score: 23.7)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair ATP-dependent DNA helicase RecQ (TIGR01389; EC 3.6.4.12; HMM-score: 21)
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 17.5)
    helicase/secretion neighborhood putative DEAH-box helicase (TIGR03817; HMM-score: 12.5)
    CRISPR-associated helicase Cas3, subtype CYANO (TIGR03158; HMM-score: 12.2)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair helicase rad25 (TIGR00603; EC 3.6.4.12; HMM-score: 10.9)
  • TheSEED: see SPJ_1590
  • PFAM:
    P-loop_NTPase (CL0023) Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 94.1)
    and 11 more
    DEAD; DEAD/DEAH box helicase (PF00270; HMM-score: 69.9)
    ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 49.8)
    OB (CL0021) RecG_wedge; RecG wedge domain (PF17191; HMM-score: 49.7)
    no clan defined RecG_dom3_C; ATP-dependent DNA helicase RecG, domain 3, C-terminal (PF19833; HMM-score: 39.7)
    P-loop_NTPase (CL0023) ERCC3_RAD25_C; ERCC3/RAD25/XPB C-terminal helicase (PF16203; HMM-score: 19.1)
    HHH (CL0198) Cdd1; Pathogenicity locus (PF11731; HMM-score: 16.9)
    no clan defined Arg_decarbox_C; Arginine decarboxylase C-terminal helical extension (PF17944; HMM-score: 16.8)
    HHH (CL0198) DNA_pol_lambd_f; Fingers domain of DNA polymerase lambda (PF10391; HMM-score: 15.2)
    P-loop_NTPase (CL0023) AAA_30; AAA domain (PF13604; HMM-score: 15.1)
    Helicase_RecD; Helicase (PF05127; HMM-score: 13.7)
    NADP_Rossmann (CL0063) Glyco_tran_WecG; Glycosyl transferase WecG/TagA/CpsF family (PF03808; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007447
    • TAT(Tat/SPI): 0.000285
    • LIPO(Sec/SPII): 0.00055
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFKTKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLADKIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFDQGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQLQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNRLLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLIGSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRILREKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVLTWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSDEKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRGDKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQVADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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