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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 05-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae JJA
- locus tag: SPJ_RS10655 [old locus tag: SPJ_2147 ]
- pan locus tag?: PNEUPAN003808000
- symbol: rgg
- pan gene symbol?: rgg
- synonym:
- product: quorum-sensing system transcriptional regulator Rgg
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SPJ_RS10655 [old locus tag: SPJ_2147 ]
- symbol: rgg
- product: quorum-sensing system transcriptional regulator Rgg
- replicon: chromosome
- strand: -
- coordinates: 1996659..1997510
- length: 852
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_012466 (1996659..1997510) NCBI
- BioCyc: SPJ_RS10655 BioCyc
- MicrobesOnline: see SPJ_2147
- PneumoBrowse for strain D39V: SPV_1952 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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841ATGGAGCAGATTGGAAAAGTCTTTAGACAATTACGAGAATCAAGAAATATCTCACTGAGA
CAAGCAACCGGAGGACAATTTTCGCCGTCTATGTTGTCCCGTTTTGAAACAGGTCAGAGT
GAGCTTTCGGTGGAAAAGTTTCTATTTGCTCTGGAAAATATATCTGCCAGTGTGGAGGAG
ATCCTCTTTCTGGCGAGAGGTTTCCAGTATGATACAGATTCTGAGTTGAGAAAAGAAATT
ACAGATGTCTTGGAACCAAAGAATATAGCACCTCTTGAGGACTTATATCGCAGGGAGTAT
CAAAAGCATGCCCATTCTCACAACAAACAGAAACATATTCTAAATGCCATTATTATCAAG
TCTTATATGAAGAGCATAGATGAAAGGGTAGACTTAACAGCAGAGGAAGGAAAAGTCCTT
CATGATTATTTGTTTTCTACCGAGATCTGGGGAATCTATGAACTCAATTTATTTTCAGTC
AGTTCTCCATTTTTATCTGTTTCTCTTTTTACTAGATATGTACGAGAAATGGTACGTAAA
TCCGATTTTCTAATGGAAATGTCTGGCAATCGAAACCTTTTTCATACTATACTATTGAAT
GGCTTTTTAGCTAGTATTGAGTGTGAAGAATTTACCAATGCCTATTATTTTAAACGTGTT
ATCGAAGAGCATTTCTACAAGGGAAATGAGACCTATTTCCGAATTGTTTATCTGTGGGCA
GAAGGTCTCCTTGATAGCAAGCAAGGTAGAGTCAAGGAAGGTCAGAAAAAGATGGAGGAT
GCTGTCCGTATTTTTGAGATGCTTGGCTGTAATAAATCTGCCGAATACTATAGAAATACG
ACCGAATGTTGA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SPJ_RS10655 [old locus tag: SPJ_2147 ]
- symbol: Rgg
- description: quorum-sensing system transcriptional regulator Rgg
- length: 283
- theoretical pI: 6.18757
- theoretical MW: 33232.6
- GRAVY: -0.409541
⊟Function[edit | edit source]
- TIGRFAM: Regulatory functions DNA interactions transcriptional activator, Rgg/GadR/MutR family, C-terminal domain (TIGR01716; HMM-score: 134.1)and 1 moreconserved hypothetical protein (TIGR02464; HMM-score: 13.5)
- TheSEED: see SPJ_2147
- PFAM: HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 18.1)HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 17.6)HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 15.5)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 1.78
- Cytoplasmic Membrane Score: 8.16
- Cellwall Score: 0.06
- Extracellular Score: 0.01
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9659
- Cytoplasmic Membrane Score: 0.0133
- Cell wall & surface Score: 0.0009
- Extracellular Score: 0.0199
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.003366
- TAT(Tat/SPI): 0.001466
- LIPO(Sec/SPII): 0.000885
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSVEKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQKHAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSVSSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFKRVIEEHFYKGNETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEYYRNTTEC
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1952 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Magda E Bortoni, Vanessa S Terra, Jason Hinds, Peter W Andrew, Hasan Yesilkaya
The pneumococcal response to oxidative stress includes a role for Rgg.
Microbiology (Reading): 2009, 155(Pt 12);4123-4134
[PubMed:19762446] [WorldCat.org] [DOI] (I p)