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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034156
  • locus tag: SPN034156_11300 [new locus tag: SPN034156_RS06350 ]
  • pan locus tag?: PNEUPAN000634000
  • symbol: SPN034156_11300
  • pan gene symbol?: dut
  • synonym:
  • product: deoxyuridine 5'-triphosphate nucleotidohydrolase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN034156_11300 [new locus tag: SPN034156_RS06350 ]
  • symbol: SPN034156_11300
  • product: deoxyuridine 5'-triphosphate nucleotidohydrolase
  • replicon: chromosome
  • strand: +
  • coordinates: 1165356..1165799
  • length: 444
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: FQ312045 (1165356..1165799) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0027 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAAATTCGTGGTTTTGAATTGGTTTCGAGTTTTACAGATGAAAATTTATTGCCCAAG
    CGTGAGACAGCGCATGCGGCTGGTTACGACTTAAAGGTTGCTGTGCGTACAGTTGTTGCG
    CCAGGAGAGATTGTCTTGGTTCCGACAGGGGTTAAGGCTTATATGCAGCCGACTGAGGTT
    CTCTACCTCTATGATCGTTCTTCAAATCCTCGTAAGAAGGGCTTGGTTTTAATTAACTCA
    GTTGGGGTCATTGATGGGGATTATTATGGAAATCCTGGAAATGAAGGGCATATTTTTGCG
    CAGATGAAGAATATCACAGACCAAGAGGTTGTTCTTGAAGTTGGGGAGCGTATTGTCCAG
    GCTGTTTTTGCTACTTTCTTAATTGCAGATGGAGATGCGGCTGATGGCGTTCGAACTGGT
    GGATTTGGATCGACAGGGCACTAG
    60
    120
    180
    240
    300
    360
    420
    444

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN034156_11300 [new locus tag: SPN034156_RS06350 ]
  • symbol: SPN034156_11300
  • description: deoxyuridine 5'-triphosphate nucleotidohydrolase
  • length: 147
  • theoretical pI: 5.19
  • theoretical MW: 15842.9
  • GRAVY: -0.0285714

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides 2'-Deoxyribonucleotide metabolism dUTP diphosphatase (TIGR00576; EC 3.6.1.23; HMM-score: 91.8)
    and 1 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides 2'-Deoxyribonucleotide metabolism deoxycytidine triphosphate deaminase (TIGR02274; EC 3.5.4.13; HMM-score: 29.6)
  • TheSEED  :
    • Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23)
    Nucleosides and Nucleotides Detoxification Housecleaning nucleoside triphosphate pyrophosphatases  Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23)
    and 1 more
    Nucleosides and Nucleotides Detoxification Nudix proteins (nucleoside triphosphate hydrolases)  Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23)
  • PFAM:
    dUTPase (CL0153) dUTPase; dUTPase (PF00692; HMM-score: 53.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9916
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0082
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.024284
    • TAT(Tat/SPI): 0.005683
    • LIPO(Sec/SPII): 0.001273
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCP36799 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEIVLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQMKNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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