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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN034156
  • locus tag: SPN034156_15910 [new locus tag: SPN034156_RS08845 ]
  • pan locus tag?: PNEUPAN001486000
  • symbol: SPN034156_15910
  • pan gene symbol?: mshD_1
  • synonym:
  • product: putative acetyltransferase, GNAT family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPN034156_15910 [new locus tag: SPN034156_RS08845 ]
  • symbol: SPN034156_15910
  • product: putative acetyltransferase, GNAT family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1643003..1643887
  • length: 885
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: FQ312045 (1643003..1643887) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0514 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGATTCAAGCAAGAAACAAGTTAAGCCAAGAAGAGCTATCTGAGGCGAAAAAAGTAATT
    AACTGTTGCCAAAACTATGACGGTACCTATCGCGATCCCTATCTCTCTAACATGCTTAAT
    TTTGATCCAAACATGCCCGCCTTTTTCCTTTATTATGAAAAAGGCGAACTTGTTGGTTTA
    TTAACTGTCTATGCAGATGACCAAGATGTAGAAGTGACGATACTGGTTCATCCAGGTCAT
    CGCCGTCAGGGGATTGCGCGTGCATTGTTTACTAGTTTTGAGAGAGGAACAGCTTCTTTC
    CCCATTCGGTCAGTCACTTTTCAGACAGAACGTATTTTTTTAGAGAATCATCCTGACTTT
    GCCAGTAACTGGGGACTAATAGAGGATGAAGAGACAGAAACTTGGTTAGGTAAGGATAGA
    AGACCTTATCCGTTAGCAAATGTTTCCCATCTTGAAGTTTTGTTAGCAGATAGTTCGTAT
    CAGGATCAAATTAGTCAATTAAAATTTCAGGCATTTTCAGAGGAACATGAATCGAGAGAA
    GTTGTGGATAGATATGTCGCTGAAGCTCTGAAGGATCCAGAAAGTCGCTTATATATTTTA
    TTAAAAGACGGTCAGGTTATTGGGACTTGTACGGTTGATTTATCGACTAATACGAATTAC
    TTCTACGGTTTAGCAATATTGGAACCTGAACGTGGAAAAGGCTATGGAAGCTACTTAGCA
    AAATCCCTCGTCAACCAACTAATTGAGCAAAATGACAAGGAATTTCAGATTGCAGTGGAA
    GATAGCAATGTAGGTGCCAAACGTTTGTATGAAAAAATTGGCTTTGTCAAACAGACTCAG
    GTGGTTTATCTGAATGAGAAAGGAGCAAGGGATTCCGAAGTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    885

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPN034156_15910 [new locus tag: SPN034156_RS08845 ]
  • symbol: SPN034156_15910
  • description: putative acetyltransferase, GNAT family protein
  • length: 294
  • theoretical pI: 4.58608
  • theoretical MW: 33671.5
  • GRAVY: -0.463946

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 59.4)
    and 5 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 42.4)
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 24.9)
    Cellular processes Cellular processes Toxin production and resistance aminoglycoside N(6')-acetyltransferase, AacA4 family (TIGR04431; EC 2.3.1.82; HMM-score: 19.6)
    GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 18.8)
    Cellular processes Cellular processes Adaptations to atypical conditions diaminobutyrate acetyltransferase (TIGR02406; EC 2.3.1.178; HMM-score: 16.6)
  • TheSEED  :
    • Acetyltransferase, GNAT family
  • PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 83.3)
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 72.3)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 67.1)
    and 10 more
    FR47; FR47-like protein (PF08445; HMM-score: 45.5)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 41.8)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 37.7)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 24.6)
    Acetyltransf_CG; GCN5-related N-acetyl-transferase (PF14542; HMM-score: 23.2)
    Acetyltransf_9; Acetyltransferase (GNAT) domain (PF13527; HMM-score: 20.6)
    Acetyltransf_18; Acetyltransferase (GNAT) domain (PF18014; HMM-score: 18.6)
    GNAT_acetyltran; GNAT acetyltransferase (PF12746; HMM-score: 16.5)
    Acetyltransf_13; ESCO1/2 acetyl-transferase (PF13880; HMM-score: 13.2)
    Acetyltransf_6; Acetyltransferase (GNAT) domain (PF13480; HMM-score: 12.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9886
    • Cytoplasmic Membrane Score: 0.0018
    • Cell wall & surface Score: 0.0035
    • Extracellular Score: 0.006
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.014588
    • TAT(Tat/SPI): 0.000356
    • LIPO(Sec/SPII): 0.016087
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CCP37260 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPNMPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERGTASFPIRSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSYQDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNTNYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFVKQTQVVYLNEKGARDSEV

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]